Nian Wang

Haifeng Wang, Hua Wu, Tian Wu et al.

In this report, we introduce ERNIE 5.0, a natively autoregressive foundation model desinged for unified multimodal understanding and generation across text, image, video, and audio. All modalities are trained from scratch under a unified next-group-of-tokens prediction objective, based on an ultra-sparse mixture-of-experts (MoE) architecture with modality-agnostic expert routing. To address practical challenges in large-scale deployment under diverse resource constraints, ERNIE 5.0 adopts a novel elastic training paradigm. Within a single pre-training run, the model learns a family of sub-models with varying depths, expert capacities, and routing sparsity, enabling flexible trade-offs among performance, model size, and inference latency in memory- or time-constrained scenarios. Moreover, we systematically address the challenges of scaling reinforcement learning to unified foundation models, thereby guaranteeing efficient and stable post-training under ultra-sparse MoE architectures and diverse multimodal settings. Extensive experiments demonstrate that ERNIE 5.0 achieves strong and balanced performance across multiple modalities. To the best of our knowledge, among publicly disclosed models, ERNIE 5.0 represents the first production-scale realization of a trillion-parameter unified autoregressive model that supports both multimodal understanding and generation. To facilitate further research, we present detailed visualizations of modality-agnostic expert routing in the unified model, alongside comprehensive empirical analysis of elastic training, aiming to offer profound insights to the community.

Jijun Xiang, Tao Wang, Jiayi Wang et al.

While Hyperspectral Anomaly Detection (HAD) excels at identifying sparse targets in complex scenes, existing models remain trapped in a scalar "reconstruction-as-endpoint" paradigm. This reliance on ambiguous scalar residuals consistently triggers sub-pixel anomaly vanishing during spatial downsampling, alongside severe confirmation bias when unpurified anomalies corrupt training weights. In this paper, we propose Reconstruction-to-Vector Diffusion (R2VD), which fundamentally redefines reconstruction as a manifold purification origin to establish a novel residual-guided generative dynamics paradigm. Our framework introduces a four-stage pipeline: (1) a Physical Prior Extraction (PPE) stage that mitigates early confirmation bias via dual-stream statistical guidance; (2) a Guided Manifold Purification (GMP) stage utilizing an OmniContext Autoencoder (OCA) to extract purified residual maps while preserving fragile sub-pixel topologies; (3) a Residual Score Modeling (RSM) stage where a Diffusion Transformer (DiT), guarded by a Physical Spectral Firewall (PSF), effectively isolates cross-spectral leakage; and (4) a Vector Dynamics Inference (VDI) stage that robustly decouples targets from backgrounds by evaluating high-dimensional vector interference patterns instead of conventional scalar errors. Comprehensive evaluations on eight datasets confirm that R2VD establishes a new state-of-the-art, delivering exceptional target detectability and background suppression. The code is available at https://github.com/Bondojijun/R2VD.

Yunwei Lan, Zhigao Cui, Chang Liu et al.

Unpaired training has been verified as one of the most effective paradigms for real scene dehazing by learning from unpaired real-world hazy and clear images. Although numerous studies have been proposed, current methods demonstrate limited generalization for various real scenes due to limited feature representation and insufficient use of real-world prior. Inspired by the strong generative capabilities of diffusion models in producing both hazy and clear images, we exploit diffusion prior for real-world image dehazing, and propose an unpaired framework named Diff-Dehazer. Specifically, we leverage diffusion prior as bijective mapping learners within the CycleGAN, a classic unpaired learning framework. Considering that physical priors contain pivotal statistics information of real-world data, we further excavate real-world knowledge by integrating physical priors into our framework. Furthermore, we introduce a new perspective for adequately leveraging the representation ability of diffusion models by removing degradation in image and text modalities, so as to improve the dehazing effect. Extensive experiments on multiple real-world datasets demonstrate the superior performance of our method. Our code https://github.com/ywxjm/Diff-Dehazer.

Yiran Song, Yikai Zhang, Shuang Zhou et al.

Multiple instance learning (MIL) has emerged as the dominant paradigm for whole slide image (WSI) analysis in computational pathology, achieving strong diagnostic performance through patch-level feature aggregation. However, existing MIL methods face critical limitations: (1) they rely on attention mechanisms that lack causal interpretability, and (2) they fail to integrate patient demographics (age, gender, race), leading to fairness concerns across diverse populations. These shortcomings hinder clinical translation, where algorithmic bias can exacerbate health disparities. We introduce \textbf{MeCaMIL}, a causality-aware MIL framework that explicitly models demographic confounders through structured causal graphs. Unlike prior approaches treating demographics as auxiliary features, MeCaMIL employs principled causal inference -- leveraging do-calculus and collider structures -- to disentangle disease-relevant signals from spurious demographic correlations. Extensive evaluation on three benchmarks demonstrates state-of-the-art performance across CAMELYON16 (ACC/AUC/F1: 0.939/0.983/0.946), TCGA-Lung (0.935/0.979/0.931), and TCGA-Multi (0.977/0.993/0.970, five cancer types). Critically, MeCaMIL achieves superior fairness -- demographic disparity variance drops by over 65% relative reduction on average across attributes, with notable improvements for underserved populations. The framework generalizes to survival prediction (mean C-index: 0.653, +0.017 over best baseline across five cancer types). Ablation studies confirm causal graph structure is essential -- alternative designs yield 0.048 lower accuracy and 4.2x times worse fairness. These results establish MeCaMIL as a principled framework for fair, interpretable, and clinically actionable AI in digital pathology. Code will be released upon acceptance.

Yunwei Lan, Zhigao Cui, Xin Luo et al.

Recent advancements in unpaired dehazing, particularly those using GANs, show promising performance in processing real-world hazy images. However, these methods tend to face limitations due to the generator's limited transport mapping capability, which hinders the full exploitation of their effectiveness in unpaired training paradigms. To address these challenges, we propose DehazeSB, a novel unpaired dehazing framework based on the Schrödinger Bridge. By leveraging optimal transport (OT) theory, DehazeSB directly bridges the distributions between hazy and clear images. This enables optimal transport mappings from hazy to clear images in fewer steps, thereby generating high-quality results. To ensure the consistency of structural information and details in the restored images, we introduce detail-preserving regularization, which enforces pixel-level alignment between hazy inputs and dehazed outputs. Furthermore, we propose a novel prompt learning to leverage pre-trained CLIP models in distinguishing hazy images and clear ones, by learning a haze-aware vision-language alignment. Extensive experiments on multiple real-world datasets demonstrate our method's superiority. Code: https://github.com/ywxjm/DehazeSB.

Juhyung Ha, Nian Wang, Surendra Maharjan et al.

This study introduces the 3D Residual-in-Residual Dense Block GAN (3D RRDB-GAN) for 3D super-resolution for radiology imagery. A key aspect of 3D RRDB-GAN is the integration of a 2.5D perceptual loss function, which contributes to improved volumetric image quality and realism. The effectiveness of our model was evaluated through 4x super-resolution experiments across diverse datasets, including Mice Brain MRH, OASIS, HCP1200, and MSD-Task-6. These evaluations, encompassing both quantitative metrics like LPIPS and FID and qualitative assessments through sample visualizations, demonstrate the models effectiveness in detailed image analysis. The 3D RRDB-GAN offers a significant contribution to medical imaging, particularly by enriching the depth, clarity, and volumetric detail of medical images. Its application shows promise in enhancing the interpretation and analysis of complex medical imagery from a comprehensive 3D perspective.

Peng Liu, Nian Wang, Cong Xu et al.

Recommender System (RS) provides personalized recommendation service based on user interest. However, lots of users' interests are sparse due to lacking consumption behaviors, making it challenging to provide accurate recommendations for them, which is widespread in large-scale RSs. In particular, efficiently solving this problem in the ranking stage of RS is an even greater challenge, which requires an end-to-end and real-time approach. To solve this problem, we propose an innovative method called Dynamic User Interest Augmentation (DUIA). DUIA enhances user interest including user profile and user history behavior sequences by generating enhancement vectors and personalized enhancement vectors through dynamic stream clustering of similar users and relevant items from multiple perspectives. To realize stream clustering, we specially design an algorithm called Gradient-based Hierarchical Clustering Algorithm (GHCA) for DUIA, which performs clustering via gradient descent and stores the cluster centers in memory networks. Extensive offline and online experiments demonstrate that DUIA not only significantly improves model performance for users with sparse interests but also delivers notable gains for other users. As an end-to-end method, DUIA can be easily integrated with existing models. Furthermore, DUIA is also used for long-tail items and cold-start problem, which also yields excellent improvements. Since 2022, DUIA has been successfully deployed in multiple industrial RSs in Tencent and was made public in May 2024. Moreover, the thoughts behind DUIA, dynamic stream clustering and similarity-based enhancement, have inspired relevant works and have also been applied in other stages of RS.

Yiran Song, Yikai Zhang, Silvia Orengo-Nania et al.

Glaucoma is one of the leading causes of irreversible blindness worldwide. Glaucoma prognosis is essential for identifying at-risk patients and enabling timely intervention to prevent blindness. Many existing approaches rely on historical sequential data but are constrained by fixed-length inputs, limiting their flexibility. Additionally, traditional glaucoma prognosis methods often employ end-to-end models, which struggle with the limited size of glaucoma datasets. To address these challenges, we propose a Two-Stage Decoupling Framework (TSDF) for variable-length glaucoma prognosis. In the first stage, we employ a feature representation module that leverages self-supervised learning to aggregate multiple glaucoma datasets for training, disregarding differences in their supervisory information. This approach enables datasets of varying sizes to learn better feature representations. In the second stage, we introduce a temporal aggregation module that incorporates an attention-based mechanism to process sequential inputs of varying lengths, ensuring flexible and efficient utilization of all available data. This design significantly enhances model performance while maintaining a compact parameter size. Extensive experiments on two benchmark glaucoma datasets:the Ocular Hypertension Treatment Study (OHTS) and the Glaucoma Real-world Appraisal Progression Ensemble (GRAPE),which differ significantly in scale and clinical settings,demonstrate the effectiveness and robustness of our approach.