Siying Wu

Feipeng Ma, Yizhou Zhou, Zheyu Zhang et al.

Recent advancements in Multimodal Large Language Models (MLLMs) have demonstrated satisfactory performance across various vision-language tasks. Current approaches for vision and language interaction fall into two categories: self-attention-based and cross-attention-based methods. However, both approaches present inherent limitations, forcing a trade-off between data and computational efficiency. To address this issue, we introduce the Data-$\textbf{E}$fficient and Compute-$\textbf{E}$fficient $\textbf{MLLM}$ ($\textbf{EE-MLLM}$). Specifically, we modify the original self-attention mechanism in MLLM to a composite attention mechanism. This mechanism has two key characteristics: 1) eliminating the computational overhead of self-attention among visual tokens to achieve $\textbf{compute efficiency}$, and 2) reusing the weights from each layer of LLM to facilitate effective vision-language modality alignment for $\textbf{data efficiency}$. As a result, EE-MLLM significantly outperforms Flamingo with limited training data, and reduces the prefilling time to 79 ms on an H800 GPU, compared to LLaVA's 277 ms. To further investigate the efficiency of EE-MLLM, we present a training-free variant named EE-MLLM-F, which reduces the computation cost of self-attention-based method without additional training. Experimental results demonstrate the effectiveness of EE-MLLM across a range of benchmarks, including general-purpose datasets like MMBench and SeedBench, as well as fine-grained tasks such as TextVQA and DocVQA.

Lubin Gan, Jing Zhang, Linhao Qu et al.

The fine-grained classification of brain tumor subtypes from histopathological whole slide images is highly challenging due to subtle morphological variations and the scarcity of annotated data. Although vision-language models have enabled promising zero-shot classification, their ability to capture fine-grained pathological features remains limited, resulting in suboptimal subtype discrimination. To address these challenges, we propose the Fine-Grained Patch Alignment Network (FG-PAN), a novel zero-shot framework tailored for digital pathology. FG-PAN consists of two key modules: (1) a local feature refinement module that enhances patch-level visual features by modeling spatial relationships among representative patches, and (2) a fine-grained text description generation module that leverages large language models to produce pathology-aware, class-specific semantic prototypes. By aligning refined visual features with LLM-generated fine-grained descriptions, FG-PAN effectively increases class separability in both visual and semantic spaces. Extensive experiments on multiple public pathology datasets, including EBRAINS and TCGA, demonstrate that FG-PAN achieves state-of-the-art performance and robust generalization in zero-shot brain tumor subtype classification.

Xiaoman Wu, Lubin Gan, Siying Wu et al.

Multi-contrast Magnetic Resonance Imaging super-resolution (MC-MRI SR) aims to enhance low-resolution (LR) contrasts leveraging high-resolution (HR) references, shortening acquisition time and improving imaging efficiency while preserving anatomical details. The main challenge lies in maintaining spatial-semantic consistency, ensuring anatomical structures remain well-aligned and coherent despite structural discrepancies and motion between the target and reference images. Conventional methods insufficiently model spatial-semantic consistency and underuse frequency-domain information, which leads to poor fine-grained alignment and inadequate recovery of high-frequency details. In this paper, we propose the Spatial-Semantic Consistent Model (SSCM), which integrates a Dynamic Spatial Warping Module for inter-contrast spatial alignment, a Semantic-Aware Token Aggregation Block for long-range semantic consistency, and a Spatial-Frequency Fusion Block for fine structure restoration. Experiments on public and private datasets show that SSCM achieves state-of-the-art performance with fewer parameters while ensuring spatially and semantically consistent reconstructions.

Lubin Gan, Xiaoman Wu, Jing Zhang et al.

Multiple instance learning (MIL) has become the leading approach for extracting discriminative features from whole slide images (WSIs) in computational pathology. Attention-based MIL methods can identify key patches but tend to overlook contextual relationships. Transformer models are able to model interactions but require quadratic computational cost and are prone to overfitting. State space models (SSMs) offer linear complexity, yet shuffling patch order disrupts histological meaning and reduces interpretability. In this work, we introduce SemaMIL, which integrates Semantic Reordering (SR), an adaptive method that clusters and arranges semantically similar patches in sequence through a reversible permutation, with a Semantic-guided Retrieval State Space Module (SRSM) that chooses a representative subset of queries to adjust state space parameters for improved global modeling. Evaluation on four WSI subtype datasets shows that, compared to strong baselines, SemaMIL achieves state-of-the-art accuracy with fewer FLOPs and parameters.

Wei Li, Hebei Li, Yansong Peng et al.

Diffusion models have significantly advanced text-to-image generation, laying the foundation for the development of personalized generative frameworks. However, existing methods lack precise layout controllability and overlook the potential of dynamic features of reference subjects in improving fidelity. In this work, we propose Layout-Controllable Personalized Diffusion (LCP-Diffusion) model, a novel framework that integrates subject identity preservation with flexible layout guidance in a tuning-free approach. Our model employs a Dynamic-Static Complementary Visual Refining module to comprehensively capture the intricate details of reference subjects, and introduces a Dual Layout Control mechanism to enforce robust spatial control across both training and inference stages. Extensive experiments validate that LCP-Diffusion excels in both identity preservation and layout controllability. To the best of our knowledge, this is a pioneering work enabling users to "create anything anywhere".