Violeta Madjarova

Maryam Viqar, Violeta Madjarova, Vipul Baghel et al.

Human veins are important for carrying the blood from the body-parts to the heart. The improper functioning of the human veins may arise from several venous diseases. Varicose vein is one such disease wherein back flow of blood can occur, often resulting in increased venous pressure or restricted blood flow due to changes in the structure of vein. To examine the functional characteristics of the varicose vein, it is crucial to study the physical and bio mechanical properties of the vein. This work proposes a segmentation model Opto-UNet, for segmenting the venous wall structure. Optical Coherence Tomography system is used to acquire images of varicose vein. As the extracted vein is not uniform in shape, hence adequate method of segmentation is required to segment the venous wall. Opto-UNet model is based on the U-Net architecture wherein a new block is integrated into the architecture, employing atrous and separable convolution to extract spatially wide-range and separable features maps for attaining advanced performance. Furthermore, the depth wise separable convolution significantly reduces the complexity of the network by optimizing the number of parameters. The model achieves accuracy of 0.9830, sensitivity of 0.8425 and specificity of 0.9980 using 8.54 million number of parameters. These results indicate that model is highly adequate in segmenting the varicose vein wall without deteriorating the segmentation quality along with reduced complexity

Maryam Viqar, Violeta Madjarova, Amit Kumar Yadav et al.

Deep-learning based segmentation model is proposed for Optical Coherence Tomography images of human varicose vein based on the U-Net model employing atrous convolution with residual blocks, which gives an accuracy of 0.9932.

Maryam Viqar, Violeta Madjarova, Elena Stoykova

Watershed segmentation method has been used in various applications. But many a times, due to its over-segmentation attributes, it underperforms in several tasks where noise is a dominant source. In this study, Optical Coherence Tomography images have been acquired, and segmentation has been performed to analyse the different regions of fluid filled sacs in a lemon. A modified watershed algorithm has been proposed which gives promising results for segmentation of internal lemon structures.

Aytaç Özkan, Elena Stoykova, Thomas Sikora et al.

In Optical Coherence Tomography (OCT), speckle noise significantly hampers image quality, affecting diagnostic accuracy. Current methods, including traditional filtering and deep learning techniques, have limitations in noise reduction and detail preservation. Addressing these challenges, this study introduces a novel denoising algorithm, Block-Matching Steered-Mixture of Experts with Multi-Model Inference and Autoencoder (BM-SMoE-AE). This method combines block-matched implementation of the SMoE algorithm with an enhanced autoencoder architecture, offering efficient speckle noise reduction while retaining critical image details. Our method stands out by providing improved edge definition and reduced processing time. Comparative analysis with existing denoising techniques demonstrates the superior performance of BM-SMoE-AE in maintaining image integrity and enhancing OCT image usability for medical diagnostics.

Maryam Viqar, Erdem Sahin, Elena Stoykova et al.

Conventional Fourier-domain Optical Coherence Tomography (FD-OCT) systems depend on resampling into wavenumber (k) domain to extract the depth profile. This either necessitates additional hardware resources or amplifies the existing computational complexity. Moreover, the OCT images also suffer from speckle noise, due to systemic reliance on low coherence interferometry. We propose a streamlined and computationally efficient approach based on Deep-Learning (DL) which enables reconstructing speckle-reduced OCT images directly from the wavelength domain. For reconstruction, two encoder-decoder styled networks namely Spatial Domain Convolution Neural Network (SD-CNN) and Fourier Domain CNN (FD-CNN) are used sequentially. The SD-CNN exploits the highly degraded images obtained by Fourier transforming the domain fringes to reconstruct the deteriorated morphological structures along with suppression of unwanted noise. The FD-CNN leverages this output to enhance the image quality further by optimization in Fourier domain (FD). We quantitatively and visually demonstrate the efficacy of the method in obtaining high-quality OCT images. Furthermore, we illustrate the computational complexity reduction by harnessing the power of DL models. We believe that this work lays the framework for further innovations in the realm of OCT image reconstruction.