Chao Chen

Lin Li, Chao Chen, Lei Pan et al.

Recently, physiological signal-based biometric systems have received wide attention. Unlike traditional biometric features, physiological signals can not be easily compromised (usually unobservable to human eyes). Photoplethysmography (PPG) signal is easy to measure, making it more attractive than many other physiological signals for biometric authentication. However, with the advent of remote PPG (rPPG), unobservability has been challenged when the attacker can remotely steal the rPPG signals by monitoring the victim's face, subsequently posing a threat to PPG-based biometrics. In PPG-based biometric authentication, current attack approaches mandate the victim's PPG signal, making rPPG-based attacks neglected. In this paper, we firstly analyze the security of PPG-based biometrics, including user authentication and communication protocols. We evaluate the signal waveforms, heart rate and inter-pulse-interval information extracted by five rPPG methods, including four traditional optical computing methods (CHROM, POS, LGI, PCA) and one deep learning method (CL_rPPG). We conducted experiments on five datasets (PURE, UBFC_rPPG, UBFC_Phys, LGI_PPGI, and COHFACE) to collect a comprehensive set of results. Our empirical studies show that rPPG poses a serious threat to the authentication system. The success rate of the rPPG signal spoofing attack in the user authentication system reached 0.35. The bit hit rate is 0.6 in inter-pulse-interval-based security protocols. Further, we propose an active defence strategy to hide the physiological signals of the face to resist the attack. It reduces the success rate of rPPG spoofing attacks in user authentication to 0.05. The bit hit rate was reduced to 0.5, which is at the level of a random guess. Our strategy effectively prevents the exposure of PPG signals to protect users' sensitive physiological data.

Aniruddha Ganguly, Debolina Chatterjee, Wentao Huang et al.

Recent advances in Spatial Transcriptomics (ST) pair histology images with spatially resolved gene expression profiles, enabling predictions of gene expression across different tissue locations based on image patches. This opens up new possibilities for enhancing whole slide image (WSI) prediction tasks with localized gene expression. However, existing methods fail to fully leverage the interactions between different tissue locations, which are crucial for accurate joint prediction. To address this, we introduce MERGE (Multi-faceted hiErarchical gRaph for Gene Expressions), which combines a multi-faceted hierarchical graph construction strategy with graph neural networks (GNN) to improve gene expression predictions from WSIs. By clustering tissue image patches based on both spatial and morphological features, and incorporating intra- and inter-cluster edges, our approach fosters interactions between distant tissue locations during GNN learning. As an additional contribution, we evaluate different data smoothing techniques that are necessary to mitigate artifacts in ST data, often caused by technical imperfections. We advocate for adopting gene-aware smoothing methods that are more biologically justified. Experimental results on gene expression prediction show that our GNN method outperforms state-of-the-art techniques across multiple metrics.