Quoc-Huy Trinh

Debesh Jha, Vanshali Sharma, Debapriya Banik et al. · oxford

Automatic analysis of colonoscopy images has been an active field of research motivated by the importance of early detection of precancerous polyps. However, detecting polyps during the live examination can be challenging due to various factors such as variation of skills and experience among the endoscopists, lack of attentiveness, and fatigue leading to a high polyp miss-rate. Deep learning has emerged as a promising solution to this challenge as it can assist endoscopists in detecting and classifying overlooked polyps and abnormalities in real time. In addition to the algorithm's accuracy, transparency and interpretability are crucial to explaining the whys and hows of the algorithm's prediction. Further, most algorithms are developed in private data, closed source, or proprietary software, and methods lack reproducibility. Therefore, to promote the development of efficient and transparent methods, we have organized the "Medico automatic polyp segmentation (Medico 2020)" and "MedAI: Transparency in Medical Image Segmentation (MedAI 2021)" competitions. We present a comprehensive summary and analyze each contribution, highlight the strength of the best-performing methods, and discuss the possibility of clinical translations of such methods into the clinic. For the transparency task, a multi-disciplinary team, including expert gastroenterologists, accessed each submission and evaluated the team based on open-source practices, failure case analysis, ablation studies, usability and understandability of evaluations to gain a deeper understanding of the models' credibility for clinical deployment. Through the comprehensive analysis of the challenge, we not only highlight the advancements in polyp and surgical instrument segmentation but also encourage qualitative evaluation for building more transparent and understandable AI-based colonoscopy systems.

Debesh Jha, Nikhil Kumar Tomar, Vanshali Sharma et al.

Colonoscopy is the primary method for examination, detection, and removal of polyps. However, challenges such as variations among the endoscopists' skills, bowel quality preparation, and the complex nature of the large intestine contribute to high polyp miss-rate. These missed polyps can develop into cancer later, underscoring the importance of improving the detection methods. To address this gap of lack of publicly available, multi-center large and diverse datasets for developing automatic methods for polyp detection and segmentation, we introduce PolypDB, a large scale publicly available dataset that contains 3934 still polyp images and their corresponding ground truth from real colonoscopy videos. PolypDB comprises images from five modalities: Blue Light Imaging (BLI), Flexible Imaging Color Enhancement (FICE), Linked Color Imaging (LCI), Narrow Band Imaging (NBI), and White Light Imaging (WLI) from three medical centers in Norway, Sweden, and Vietnam. We provide a benchmark on each modality and center, including federated learning settings using popular segmentation and detection benchmarks. PolypDB is public and can be downloaded at \url{https://osf.io/pr7ms/}. More information about the dataset, segmentation, detection, federated learning benchmark and train-test split can be found at \url{https://github.com/DebeshJha/PolypDB}.

Quoc-Huy Trinh, Nhat-Tan Bui, Trong-Hieu Nguyen Mau et al.

Polyp segmentation has recently garnered significant attention, and multiple methods have been formulated to achieve commendable outcomes. However, these techniques often confront difficulty when working with the complex polyp foreground and their surrounding regions because of the nature of convolution operation. Besides, most existing methods forget to exploit the potential information from multiple decoder stages. To address this challenge, we suggest combining MetaFormer, introduced as a baseline for integrating CNN and Transformer, with UNet framework and incorporating our Multi-scale Upsampling block (MU). This simple module makes it possible to combine multi-level information by exploring multiple receptive field paths of the shallow decoder stage and then adding with the higher stage to aggregate better feature representation, which is essential in medical image segmentation. Taken all together, we propose MetaFormer Multi-scale Upsampling Network (M$^2$UNet) for the polyp segmentation task. Extensive experiments on five benchmark datasets demonstrate that our method achieved competitive performance compared with several previous methods.

Quoc-Huy Trinh, Minh-Van Nguyen, Thien-Phuc Nguyen Dinh

One of the most contentious areas of research in Medical Image Preprocessing is 3D CT-scan. With the rapid spread of COVID-19, the function of CT-scan in properly and swiftly diagnosing the disease has become critical. It has a positive impact on infection prevention. There are many tasks to diagnose the illness through CT-scan images, include COVID-19. In this paper, we propose a method that using a Stacking Deep Neural Network to detect the Covid 19 through the series of 3D CT-scans images . In our method, we experiment with two backbones are DenseNet 121 and ResNet 101. This method achieves a competitive performance on some evaluation metrics

Trong-Hieu Nguyen Mau, Quoc-Huy Trinh, Nhat-Tan Bui et al.

Medical image segmentation is the technique that helps doctor view and has a precise diagnosis, particularly in Colorectal Cancer. Specifically, with the increase in cases, the diagnosis and identification need to be faster and more accurate for many patients; in endoscopic images, the segmentation task has been vital to helping the doctor identify the position of the polyps or the ache in the system correctly. As a result, many efforts have been made to apply deep learning to automate polyp segmentation, mostly to ameliorate the U-shape structure. However, the simple skip connection scheme in UNet leads to deficient context information and the semantic gap between feature maps from the encoder and decoder. To deal with this problem, we propose a novel framework composed of ConvNeXt backbone and Multi Kernel Positional Embedding block. Thanks to the suggested module, our method can attain better accuracy and generalization in the polyps segmentation task. Extensive experiments show that our model achieves the Dice coefficient of 0.8818 and the IOU score of 0.8163 on the Kvasir-SEG dataset. Furthermore, on various datasets, we make competitive achievement results with other previous state-of-the-art methods.

Quoc-Huy Trinh, Trong-Hieu Nguyen Mau, Radmir Zosimov et al.

In the development of technology, there are increasing cases of brain disease, there are more treatments proposed and achieved a positive result. However, with Brain-Lesion, the early diagnoses can improve the possibility for successful treatment and can help patients recuperate better. From this reason, Brain-Lesion is one of the controversial topics in medical images analysis nowadays. With the improvement of the architecture, there is a variety of methods that are proposed and achieve competitive scores. In this paper, we proposed a technique that uses efficient-net for 3D images, especially the Efficient-net B0 for Brain-Lesion classification task solution, and achieve the competitive score. Moreover, we also proposed the method to use Multiscale-EfficientNet to classify the slices of the MRI data

Nhat-Tan Bui, Dinh-Hieu Hoang, Quoc-Huy Trinh et al.

Negation is a fundamental linguistic concept used by humans to convey information that they do not desire. Despite this, minimal research has focused on negation within text-guided image editing. This lack of research means that vision-language models (VLMs) for image editing may struggle to understand negation, implying that they struggle to provide accurate results. One barrier to achieving human-level intelligence is the lack of a standard collection by which research into negation can be evaluated. This paper presents the first large-scale dataset, Negative Instruction (NeIn), for studying negation within instruction-based image editing. Our dataset comprises 366,957 quintuplets, i.e., source image, original caption, selected object, negative sentence, and target image in total, including 342,775 queries for training and 24,182 queries for benchmarking image editing methods. Specifically, we automatically generate NeIn based on a large, existing vision-language dataset, MS-COCO, via two steps: generation and filtering. During the generation phase, we leverage two VLMs, BLIP and InstructPix2Pix (fine-tuned on MagicBrush dataset), to generate NeIn's samples and the negative clauses that expresses the content of the source image. In the subsequent filtering phase, we apply BLIP and LLaVA-NeXT to remove erroneous samples. Additionally, we introduce an evaluation protocol to assess the negation understanding for image editing models. Extensive experiments using our dataset across multiple VLMs for text-guided image editing demonstrate that even recent state-of-the-art VLMs struggle to understand negative queries.

Quoc-Huy Trinh, Xi Ding, Yang Liu et al.

Visual spatial intelligence is critical for medical image interpretation, yet remains largely unexplored in Multimodal Large Language Models (MLLMs) for 3D imaging. This gap persists due to a systemic lack of datasets featuring structured 3D spatial annotations beyond basic labels. In this study, we introduce an agentic pipeline that autonomously synthesizes spatial visual question-answering (VQA) data by orchestrating computational tools such as volume and distance calculators with multi-agent collaboration and expert radiologist validation. We present SpatialMed, the first comprehensive benchmark for evaluating 3D spatial intelligence in medical MLLMs, comprising nearly 10K question-answer pairs across multiple organs and tumor types. Our evaluations on 14 state-of-the-art MLLMs and extensive analyses reveal that current models lack robust spatial reasoning capabilities for medical imaging.

Quoc-Huy Trinh, Minh-Van Nguyen, Phuoc-Thao Vo Thi

Polyp segmentation, a contentious issue in medical imaging, has seen numerous proposed methods aimed at improving the quality of segmented masks. While current state-of-the-art techniques yield impressive results, the size and computational cost of these models create challenges for practical industry applications. To address this challenge, we present KDAS, a Knowledge Distillation framework that incorporates attention supervision, and our proposed Symmetrical Guiding Module. This framework is designed to facilitate a compact student model with fewer parameters, allowing it to learn the strengths of the teacher model and mitigate the inconsistency between teacher features and student features, a common challenge in Knowledge Distillation, via the Symmetrical Guiding Module. Through extensive experiments, our compact models demonstrate their strength by achieving competitive results with state-of-the-art methods, offering a promising approach to creating compact models with high accuracy for polyp segmentation and in the medical imaging field. The implementation is available on https://github.com/huyquoctrinh/KDAS.

Minh-Van Nguyen, Duy-Thinh Nguyen, Quoc-Huy Trinh et al.

Medication recommendation is a vital task for improving patient care and reducing adverse events. However, existing methods often fail to capture the complex and dynamic relationships among patient medical records, drug efficacy and safety, and drug-drug interactions (DDI). In this paper, we propose ALGNet, a novel model that leverages light graph convolutional networks (LGCN) and augmentation memory networks (AMN) to enhance medication recommendation. LGCN can efficiently encode the patient records and the DDI graph into low-dimensional embeddings, while AMN can augment the patient representation with external knowledge from a memory module. We evaluate our model on the MIMIC-III dataset and show that it outperforms several baselines in terms of recommendation accuracy and DDI avoidance. We also conduct an ablation study to analyze the effects of different components of our model. Our results demonstrate that ALGNet can achieve superior performance with less computation and more interpretability. The implementation of this paper can be found at: https://github.com/huyquoctrinh/ALGNet.

Quoc-Huy Trinh, Nhat-Tan Bui, Dinh-Hieu Hoang et al.

Person Re-Identification (Re-ID) task seeks to enhance the tracking of multiple individuals by surveillance cameras. It supports multimodal tasks, including text-based person retrieval and human matching. One of the most significant challenges faced in Re-ID is clothes-changing, where the same person may appear in different outfits. While previous methods have made notable progress in maintaining clothing data consistency and handling clothing change data, they still rely excessively on clothing information, which can limit performance due to the dynamic nature of human appearances. To mitigate this challenge, we propose the Pose-Guidance Deep Supervision (PGDS), an effective framework for learning pose guidance within the Re-ID task. It consists of three modules: a human encoder, a pose encoder, and a Pose-to-Human Projection module (PHP). Our framework guides the human encoder, i.e., the main re-identification model, with pose information from the pose encoder through multiple layers via the knowledge transfer mechanism from the PHP module, helping the human encoder learn body parts information without increasing computation resources in the inference stage. Through extensive experiments, our method surpasses the performance of current state-of-the-art methods, demonstrating its robustness and effectiveness for real-world applications. Our code is available at https://github.com/huyquoctrinh/PGDS.

Quoc-Huy Trinh, Mustapha Abdullahi, Do Duy Hung Trinh et al.

Recent advances in multimodal large language models (MLLMs) have enabled impressive progress in vision-language understanding, yet their high computational cost limits deployment in resource-constrained scenarios such as robotic manipulation, personal assistants, and smart cameras. Most existing methods rely on Transformer-based cross-attention, whose quadratic complexity hinders efficiency. Moreover, small vision-language models often struggle to precisely capture fine-grained, task-relevant visual regions, leading to degraded performance on fine-grained reasoning tasks that limit their effectiveness in the real world. To address these issues, we introduce Viper-F1, a Hybrid State-Space Vision-Language Model that replaces attention with efficient Liquid State-Space Dynamics. To further enhance visual grounding, we propose a Token-Grid Correlation Module, which computes lightweight correlations between text tokens and image patches and modulates the state-space dynamics via FiLM conditioning. This enables the model to selectively emphasize visual regions relevant to the textual prompt while maintaining linear-time inference. Experimental results across multiple benchmarks demonstrate that Viper-F1 achieves accurate, fine-grained understanding with significantly improved efficiency.

Jun Zeng, Yannan Huang, Elif Keles et al.

Liver Cirrhosis plays a critical role in the prognosis of chronic liver disease. Early detection and timely intervention are critical in significantly reducing mortality rates. However, the intricate anatomical architecture and diverse pathological changes of liver tissue complicate the accurate detection and characterization of lesions in clinical settings. Existing methods underutilize the spatial anatomical details in volumetric MRI data, thereby hindering their clinical effectiveness and explainability. To address this challenge, we introduce a novel Mamba-based network, SRMA-Mamba, designed to model the spatial relationships within the complex anatomical structures of MRI volumes. By integrating the Spatial Anatomy-Based Mamba module (SABMamba), SRMA-Mamba performs selective Mamba scans within liver cirrhotic tissues and combines anatomical information from the sagittal, coronal, and axial planes to construct a global spatial context representation, enabling efficient volumetric segmentation of pathological liver structures. Furthermore, we introduce the Spatial Reverse Attention module (SRMA), designed to progressively refine cirrhotic details in the segmentation map, utilizing both the coarse segmentation map and hierarchical encoding features. Extensive experiments demonstrate that SRMA-Mamba surpasses state-of-the-art methods, delivering exceptional performance in 3D pathological liver segmentation. Our code is available for public: https://github.com/JunZengz/SRMA-Mamba.

Quoc-Huy Trinh

In recent years, polyp segmentation has gained significant importance, and many methods have been developed using CNN, Vision Transformer, and Transformer techniques to achieve competitive results. However, these methods often face difficulties when dealing with out-of-distribution datasets, missing boundaries, and small polyps. In 2022, Meta-Former was introduced as a new baseline for vision, which not only improved the performance of multi-task computer vision but also addressed the limitations of the Vision Transformer and CNN family backbones. To further enhance segmentation, we propose a fusion of Meta-Former with UNet, along with the introduction of a Multi-scale Upsampling block with a level-up combination in the decoder stage to enhance the texture, also we propose the Convformer block base on the idea of the Meta-former to enhance the crucial information of the local feature. These blocks enable the combination of global information, such as the overall shape of the polyp, with local information and boundary information, which is crucial for the decision of the medical segmentation. Our proposed approach achieved competitive performance and obtained the top result in the State of the Art on the CVC-300 dataset, Kvasir, and CVC-ColonDB dataset. Apart from Kvasir-SEG, others are out-of-distribution datasets. The implementation can be found at: https://github.com/huyquoctrinh/MetaPolyp-CBMS2023.

Quoc-Bao Nguyen-Le, Tuan-Hy Le, Anh-Triet Do et al.

Cardiovascular disease remains a predominant global health concern, responsible for a significant portion of mortality worldwide. Accurate segmentation of cardiac medical imaging data is pivotal in mitigating fatality rates associated with cardiovascular conditions. However, existing state-of-the-art (SOTA) neural networks, including both CNN-based and Transformer-based approaches, exhibit limitations in practical applicability due to their inability to effectively capture inter-slice connections alongside intra-slice information. This deficiency is particularly evident in datasets featuring intricate, long-range details along the z-axis, such as coronary arteries in axial views. Additionally, SOTA methods fail to differentiate non-cardiac components from myocardium in segmentation, leading to the "spraying" phenomenon. To address these challenges, we present RotCAtt-TransUNet++, a novel architecture tailored for robust segmentation of complex cardiac structures. Our approach emphasizes modeling global contexts by aggregating multiscale features with nested skip connections in the encoder. It integrates transformer layers to capture interactions between patches and employs a rotatory attention mechanism to capture connectivity between multiple slices (inter-slice information). Additionally, a channel-wise cross-attention gate guides the fused multi-scale channel-wise information and features from decoder stages to bridge semantic gaps. Experimental results demonstrate that our proposed model outperforms existing SOTA approaches across four cardiac datasets and one abdominal dataset. Importantly, coronary arteries and myocardium are annotated with near-perfect accuracy during inference. An ablation study shows that the rotatory attention mechanism effectively transforms embedded vectorized patches in the semantic dimensional space, enhancing segmentation accuracy.

Quoc-Huy Trinh, Minh-Van Nguyen, Jung Zeng et al.

Recent advancements in prompt-based medical image segmentation have enabled clinicians to identify tumors using simple input like bounding boxes or text prompts. However, existing methods face challenges when doctors need to interact through natural language or when position reasoning is required - understanding spatial relationships between anatomical structures and pathologies. We present PRS-Med, a framework that integrates vision-language models with segmentation capabilities to generate both accurate segmentation masks and corresponding spatial reasoning outputs. Additionally, we introduce the MMRS dataset (Multimodal Medical in Positional Reasoning Segmentation), which provides diverse, spatially-grounded question-answer pairs to address the lack of position reasoning data in medical imaging. PRS-Med demonstrates superior performance across six imaging modalities (CT, MRI, X-ray, ultrasound, endoscopy, RGB), significantly outperforming state-of-the-art methods in both segmentation accuracy and position reasoning. Our approach enables intuitive doctor-system interaction through natural language, facilitating more efficient diagnoses. Our dataset pipeline, model, and codebase will be released to foster further research in spatially-aware multimodal reasoning for medical applications.

Quoc-Huy Trinh, Mustapha Abdullahi, Bo Zhao et al.

Recent advances in multimodal large language models (MLLMs) have enabled impressive progress in vision-language understanding, yet their high computational cost limits deployment in resource-constrained scenarios such as personal assistants, document understanding, and smart cameras. Most existing methods rely on Transformer-based cross-attention, whose quadratic complexity hinders efficiency. Moreover, small vision-language models often struggle to precisely capture fine-grained, task-relevant visual regions, leading to degraded performance on fine-grained reasoning tasks that limit their effectiveness in the real world. To address these issues, we introduce Firebolt-VL, an efficient vision-language model that replaces the Transformer-based decoder with a Liquid Foundation Model (LFM) decoder. To further enhance visual grounding, we propose a Token-Grid Correlation Module, which computes lightweight correlations between text tokens and image patches and modulates via the state-space model with FiLM conditioning. This enables the model to selectively emphasize visual regions relevant to the textual prompt while maintaining linear-time inference. Experimental results across multiple benchmarks demonstrate that Firebolt-VL achieves accurate, fine-grained understanding with significantly improved efficiency. Our model and code are available at: https://fireboltvl.github.io

Quoc-Huy Trinh, Minh-Van Nguyen, Trong-Hieu Nguyen Mau et al.

Singing is one of the most cherished forms of human entertainment. However, creating a beautiful song requires an accompaniment that complements the vocals and aligns well with the song instruments and genre. With advancements in deep learning, previous research has focused on generating suitable accompaniments but often lacks precise alignment with the desired instrumentation and genre. To address this, we propose a straightforward method that enables control over the accompaniment through text prompts, allowing the generation of music that complements the vocals and aligns with the song instrumental and genre requirements. Through extensive experiments, we successfully generate 10-second accompaniments using vocal input and text control.

Quoc-Huy Trinh, Hai-Dang Nguyen, Bao-Tram Nguyen Ngoc et al.

Polyp segmentation, a critical concern in medical imaging, has prompted numerous proposed methods aimed at enhancing the quality of segmented masks. While current state-of-the-art techniques produce impressive results, the size and computational cost of these models pose challenges for practical industry applications. Recently, the Segment Anything Model (SAM) has been proposed as a robust foundation model, showing promise for adaptation to medical image segmentation. Inspired by this concept, we propose SAM-EG, a framework that guides small segmentation models for polyp segmentation to address the computation cost challenge. Additionally, in this study, we introduce the Edge Guiding module, which integrates edge information into image features to assist the segmentation model in addressing boundary issues from current segmentation model in this task. Through extensive experiments, our small models showcase their efficacy by achieving competitive results with state-of-the-art methods, offering a promising approach to developing compact models with high accuracy for polyp segmentation and in the broader field of medical imaging.

Quoc-Huy Trinh, Minh-Van Nguyen, Thiet-Gia Huynh et al.

The Medico: Multimedia Task 2020 focuses on developing an efficient and accurate computer-aided diagnosis system for automatic segmentation [3]. We participate in task 1, Polyps segmentation task, which is to develop algorithms for segmenting polyps on a comprehensive dataset. In this task, we propose methods combining Residual module, Inception module, Adaptive Convolutional neural network with U-Net model, and PraNet for semantic segmentation of various types of polyps in endoscopic images. We select 5 runs with different architecture and parameters in our methods. Our methods show potential results in accuracy and efficiency through multiple experiments, and our team is in the Top 3 best results with a Jaccard index of 0.765.