Jian Sun

Jian Sun, Hiroko H. Dodge, Mohammad H. Mahoor

Deep machine learning models including Convolutional Neural Networks (CNN) have been successful in the detection of Mild Cognitive Impairment (MCI) using medical images, questionnaires, and videos. This paper proposes a novel Multi-branch Classifier-Video Vision Transformer (MC-ViViT) model to distinguish MCI from those with normal cognition by analyzing facial features. The data comes from the I-CONECT, a behavioral intervention trial aimed at improving cognitive function by providing frequent video chats. MC-ViViT extracts spatiotemporal features of videos in one branch and augments representations by the MC module. The I-CONECT dataset is challenging as the dataset is imbalanced containing Hard-Easy and Positive-Negative samples, which impedes the performance of MC-ViViT. We propose a loss function for Hard-Easy and Positive-Negative Samples (HP Loss) by combining Focal loss and AD-CORRE loss to address the imbalanced problem. Our experimental results on the I-CONECT dataset show the great potential of MC-ViViT in predicting MCI with a high accuracy of 90.63% accuracy on some of the interview videos.

Muath Alsuhaibani, Ali Pourramezan Fard, Jian Sun et al.

This review paper explores recent advances in deep learning approaches for non-invasive cognitive impairment detection. We examine various non-invasive indicators of cognitive decline, including speech and language, facial, and motoric mobility. The paper provides an overview of relevant datasets, feature-extracting techniques, and deep-learning architectures applied to this domain. We have analyzed the performance of different methods across modalities and observed that speech and language-based methods generally achieved the highest detection performance. Studies combining acoustic and linguistic features tended to outperform those using a single modality. Facial analysis methods showed promise for visual modalities but were less extensively studied. Most papers focused on binary classification (impaired vs. non-impaired), with fewer addressing multi-class or regression tasks. Transfer learning and pre-trained language models emerged as popular and effective techniques, especially for linguistic analysis. Despite significant progress, several challenges remain, including data standardization and accessibility, model explainability, longitudinal analysis limitations, and clinical adaptation. Lastly, we propose future research directions, such as investigating language-agnostic speech analysis methods, developing multi-modal diagnostic systems, and addressing ethical considerations in AI-assisted healthcare. By synthesizing current trends and identifying key obstacles, this review aims to guide further development of deep learning-based cognitive impairment detection systems to improve early diagnosis and ultimately patient outcomes.

Jian Sun, Ali Pourramezan Fard, Mohammad H. Mahoor

Capsule Network is powerful at defining the positional relationship between features in deep neural networks for visual recognition tasks, but it is computationally expensive and not suitable for running on mobile devices. The bottleneck is in the computational complexity of the Dynamic Routing mechanism used between the capsules. On the other hand, XNOR-Net is fast and computationally efficient, though it suffers from low accuracy due to information loss in the binarization process. To address the computational burdens of the Dynamic Routing mechanism, this paper proposes new Fully Connected (FC) layers by xnorizing the linear projection outside or inside the Dynamic Routing within the CapsFC layer. Specifically, our proposed FC layers have two versions, XnODR (Xnorize the Linear Projection Outside Dynamic Routing) and XnIDR (Xnorize the Linear Projection Inside Dynamic Routing). To test the generalization of both XnODR and XnIDR, we insert them into two different networks, MobileNetV2 and ResNet-50. Our experiments on three datasets, MNIST, CIFAR-10, and MultiMNIST validate their effectiveness. The results demonstrate that both XnODR and XnIDR help networks to have high accuracy with lower FLOPs and fewer parameters (e.g., 96.14% correctness with 2.99M parameters and 311.74M FLOPs on CIFAR-10).