Liang Zhong

Doyoung Park, Jinsoo Kim, Qi Chang et al.

The Agatston score, which is the sum of the calcification in the four main coronary arteries, has been widely used in the diagnosis of coronary artery disease (CAD). However, many studies have emphasized the importance of the vessel-specific Agatston score, as calcification in a specific vessel is significantly correlated with the occurrence of coronary heart disease (CHD). In this paper, we propose the Residual-block Inspired Coordinate Attention U-Net (RICAU-Net), which incorporates coordinate attention in two distinct manners and a customized combo loss function for lesion-specific coronary artery calcium (CAC) segmentation. This approach aims to tackle the high class-imbalance issue associated with small and sparse CAC lesions. Experimental results and the ablation study demonstrate that the proposed method outperforms the five other U-Net based methods used in medical applications, by achieving the highest per-lesion Dice scores across all four lesions.

Peng Sun, Liang Zhong, Qing-Guo Zeng et al.

The rapid deployment of electric vehicles (EVs) in public parking facilities and fleet operations raises challenging intra-day charging scheduling problems under tight charger capacity and limited dwell times. We model this problem as a variant of the Partition Coloring Problem (PCP), where each vehicle defines a partition, its candidate charging intervals are vertices, and temporal and resource conflicts are represented as edges in a conflict graph. On this basis, we design a branch-and-price algorithm in which the restricted master problem selects feasible combinations of intervals, and the pricing subproblem is a maximum independent set problem. The latter is reformulated as a quadratic unconstrained binary optimization (QUBO) model and solved by quantum-annealing-inspired algorithms (QAIA) implemented in the MindQuantum framework, specifically the ballistic simulated branching (BSB) and simulated coherent Ising machine (SimCIM) methods, while the master problem is solved by Gurobi. Computational experiments on a family of synthetic EV charging instances show that the QAIA-enhanced algorithms match the pure Gurobi-based branch-and-price baseline on small and medium instances, and clearly outperform it on large and hard instances. In several cases where the baseline reaches the time limit with non-zero optimality gaps, the QAIA-based variants close the gap and prove optimality within the same time budget. These results indicate that integrating QAIA into classical decomposition schemes are a promising direction for large-scale EV charging scheduling and related PCP applications.

Yikun Ma, Bo Li, Ying Chen et al.

The early detection of esophagogastric junction adenocarcinoma (EGJA) is crucial for improving patient prognosis, yet its current diagnosis is highly operator-dependent. This paper aims to make the first attempt to develop an artificial intelligence (AI) foundation model-based method for both screening and staging diagnosis of EGJA using endoscopic images. In this cohort and learning study, we conducted a multicentre study across seven Chinese hospitals between December 28, 2016 and December 30, 2024. It comprises 12,302 images from 1,546 patients; 8,249 of them were employed for model training, while the remaining were divided into the held-out (112 patients, 914 images), external (230 patients, 1,539 images), and prospective (198 patients, 1,600 images) test sets for evaluation. The proposed model employs DINOv2 (a vision foundation model) and ResNet50 (a convolutional neural network) to extract features of global appearance and local details of endoscopic images for EGJA staging diagnosis. Our model demonstrates satisfactory performance for EGJA staging diagnosis across three test sets, achieving an accuracy of 0.9256, 0.8895, and 0.8956, respectively. In contrast, among representative AI models, the best one (ResNet50) achieves an accuracy of 0.9125, 0.8382, and 0.8519 on the three test sets, respectively; the expert endoscopists achieve an accuracy of 0.8147 on the held-out test set. Moreover, with the assistance of our model, the overall accuracy for the trainee, competent, and expert endoscopists improves from 0.7035, 0.7350, and 0.8147 to 0.8497, 0.8521, and 0.8696, respectively. To our knowledge, our model is the first application of foundation models for EGJA staging diagnosis and demonstrates great potential in both diagnostic accuracy and efficiency.

Phongsakon Mark Konrad, Andrei-Alexandru Popa, Yaser Sabzehmeidani et al.

Accurate segmentation of carotid artery structures in histopathological images is vital for advancing cardiovascular disease research and diagnosis. However, deep learning model development in this domain is constrained by the scarcity of annotated cardiovascular histopathological data. This study investigates a systematic evaluation of state-of-the-art deep learning segmentation models, including convolutional neural networks (U-Net, DeepLabV3+), a Vision Transformer (SegFormer), and recent foundation models (SAM, MedSAM, MedSAM+UNet), on a limited dataset of cardiovascular histology images. Despite employing an extensive hyperparameter optimization strategy with Bayesian search, our findings reveal that model performance is highly sensitive to data splits, with minor differences driven more by statistical noise than by true algorithmic superiority. This instability exposes the limitations of standard benchmarking practices in low-data clinical settings and challenges the assumption that performance rankings reflect meaningful clinical utility.

Yiwei Liu, Ziyi Wu, Liang Zhong et al.

Existing models typically segment either the entire 3D frame or 2D slices independently to derive clinical functional metrics from ventricular segmentation in cardiac cine sequences. While performing well overall, they struggle at the end slices. To address this, we leverage spatial continuity to extract global uncertainty from segmentation variance and use it as memory in our ensemble learning method, Streaming, for classifier weighting, balancing overall and end-slice performance. Additionally, we introduce the End Coefficient (EC) to quantify end-slice accuracy. Experiments on ACDC and M&Ms datasets show that our framework achieves near-state-of-the-art Dice Similarity Coefficient (DSC) and outperforms all models on end-slice performance, improving patient-specific segmentation accuracy.