Haitao Sun

Anbang Wang, Difei Mei, Zhichao Zhang et al.

This paper presents ReverseNER, a method aimed at overcoming the limitation of large language models (LLMs) in zero-shot named entity recognition (NER) tasks, arising from their reliance on pre-provided demonstrations. ReverseNER tackles this challenge by constructing a reliable example library composed of dozens of entity-labeled sentences, generated through the reverse process of NER. Specifically, while conventional NER methods label entities in a sentence, ReverseNER features reversing the process by using an LLM to generate entities from their definitions and subsequently expand them into full sentences. During the entity expansion process, the LLM is guided to generate sentences by replicating the structures of a set of specific \textsl{feature sentences}, extracted from the task sentences by clustering. This expansion process produces dozens of entity-labeled task-relevant sentences. After constructing the example library, the method selects several semantically similar entity-labeled examples for each task sentence as references to facilitate the LLM's entity recognition. We also propose an entity-level self-consistency scoring mechanism to improve NER performance with LLMs. Experiments show that ReverseNER significantly outperforms other zero-shot NER methods with LLMs, marking a notable improvement in NER for domains without labeled data, while declining computational resource consumption.

Zhuo Xiao, Fugen Zhou, Jingjing Wang et al.

Accurate multi-needle localization in intraoperative CT images is crucial for optimizing seed placement in pelvic seed implant brachytherapy. However, this task is challenging due to poor image contrast and needle adhesion. This paper presents a novel approach that reframes needle localization as a tip-handle detection and matching problem to overcome these difficulties. An anchor-free network, based on HRNet, is proposed to extract multi-scale features and accurately detect needle tips and handles by predicting their centers and orientations using decoupled branches for heatmap regression and polar angle prediction. To associate detected tips and handles into individual needles, a greedy matching and merging (GMM) method designed to solve the unbalanced assignment problem with constraints (UAP-C) is presented. The GMM method iteratively selects the most probable tip-handle pairs and merges them based on a distance metric to reconstruct 3D needle paths. Evaluated on a dataset of 100 patients, the proposed method demonstrates superior performance, achieving higher precision and F1 score compared to a segmentation-based method utilizing the nnUNet model,thereby offering a more robust and accurate solution for needle localization in complex clinical scenarios.

Zhuo Xiao, Qinglong Yao, Jingjing Wang et al.

Seed implant brachytherapy (SIBT) is an effective cancer treatment modality; however, clinical planning often relies on manual adjustment of objective function weights, leading to inefficiencies and suboptimal results. This study proposes an adaptive weight optimization framework for SIBT planning, driven by large language models (LLMs). A locally deployed DeepSeek-R1 LLM is integrated with an automatic planning algorithm in an iterative loop. Starting with fixed weights, the LLM evaluates plan quality and recommends new weights in the next iteration. This process continues until convergence criteria are met, after which the LLM conducts a comprehensive evaluation to identify the optimal plan. A clinical knowledge base, constructed and queried via retrieval-augmented generation (RAG), enhances the model's domain-specific reasoning. The proposed method was validated on 23 patient cases, showing that the LLM-assisted approach produces plans that are comparable to or exceeding clinically approved and fixed-weight plans, in terms of dose homogeneity for the clinical target volume (CTV) and sparing of organs at risk (OARs). The study demonstrates the potential use of LLMs in SIBT planning automation.