Jiayang Zhang

Hang Du, Sicheng Zhang, Binzhu Xie et al.

Video anomaly understanding (VAU) aims to automatically comprehend unusual occurrences in videos, thereby enabling various applications such as traffic surveillance and industrial manufacturing. While existing VAU benchmarks primarily concentrate on anomaly detection and localization, our focus is on more practicality, prompting us to raise the following crucial questions: "what anomaly occurred?", "why did it happen?", and "how severe is this abnormal event?". In pursuit of these answers, we present a comprehensive benchmark for Causation Understanding of Video Anomaly (CUVA). Specifically, each instance of the proposed benchmark involves three sets of human annotations to indicate the "what", "why" and "how" of an anomaly, including 1) anomaly type, start and end times, and event descriptions, 2) natural language explanations for the cause of an anomaly, and 3) free text reflecting the effect of the abnormality. In addition, we also introduce MMEval, a novel evaluation metric designed to better align with human preferences for CUVA, facilitating the measurement of existing LLMs in comprehending the underlying cause and corresponding effect of video anomalies. Finally, we propose a novel prompt-based method that can serve as a baseline approach for the challenging CUVA. We conduct extensive experiments to show the superiority of our evaluation metric and the prompt-based approach. Our code and dataset are available at https://github.com/fesvhtr/CUVA.

Jiayang Zhang, Xianyuan Liu, Wei Wu et al.

Virus-like particles (VLPs) are valuable for vaccine development due to their immune-triggering properties. Understanding their stoichiometry, the number of protein subunits to form a VLP, is critical for vaccine optimisation. However, current experimental methods to determine stoichiometry are time-consuming and require highly purified proteins. To efficiently classify stoichiometry classes in proteins, we curate a new dataset and propose an interpretable, data-driven pipeline leveraging linear machine learning models. We also explore the impact of feature encoding on model performance and interpretability, as well as methods to identify key protein sequence features influencing classification. The evaluation of our pipeline demonstrates that it can classify stoichiometry while revealing protein features that possibly influence VLP assembly. The data and code used in this work are publicly available at https://github.com/Shef-AIRE/StoicIML.

Xianyuan Liu, Jiayang Zhang, Shuo Zhou et al.

Multimodal artificial intelligence (AI) integrates diverse types of data via machine learning to improve understanding, prediction, and decision-making across disciplines such as healthcare, science, and engineering. However, most multimodal AI advances focus on models for vision and language data, while their deployability remains a key challenge. We advocate a deployment-centric workflow that incorporates deployment constraints early to reduce the likelihood of undeployable solutions, complementing data-centric and model-centric approaches. We also emphasise deeper integration across multiple levels of multimodality and multidisciplinary collaboration to significantly broaden the research scope beyond vision and language. To facilitate this approach, we identify common multimodal-AI-specific challenges shared across disciplines and examine three real-world use cases: pandemic response, self-driving car design, and climate change adaptation, drawing expertise from healthcare, social science, engineering, science, sustainability, and finance. By fostering multidisciplinary dialogue and open research practices, our community can accelerate deployment-centric development for broad societal impact.

Hang Du, Jiayang Zhang, Guoshun Nan et al.

Multi-image Interleaved Reasoning aims to improve Multi-modal Large Language Models (MLLMs) ability to jointly comprehend and reason across multiple images and their associated textual contexts, introducing unique challenges beyond single-image or non-interleaved multi-image tasks. While current multi-image benchmarks overlook interleaved textual contexts and neglect distinct relationships between individual images and their associated texts, enabling models to reason over multi-image interleaved data may significantly enhance their comprehension of complex scenes and better capture cross-modal correlations. To bridge this gap, we introduce a novel benchmark MIR, requiring joint reasoning over multiple images accompanied by interleaved textual contexts to accurately associate image regions with corresponding texts and logically connect information across images. To enhance MLLMs ability to comprehend multi-image interleaved data, we introduce reasoning steps for each instance within the benchmark and propose a stage-wise curriculum learning strategy. This strategy follows an "easy to hard" approach, progressively guiding models from simple to complex scenarios, thereby enhancing their ability to handle challenging tasks. Extensive experiments benchmarking multiple MLLMs demonstrate that our method significantly enhances models reasoning performance on MIR and other established benchmarks. We believe that MIR will encourage further research into multi-image interleaved reasoning, facilitating advancements in MLLMs capability to handle complex inter-modal tasks.

Wenrui Fan, L. M. Riza Rizky, Jiayang Zhang et al.

Neuropathic pain, affecting up to 10% of adults, remains difficult to treat due to limited therapeutic efficacy and tolerability. Although resting-state functional MRI (rs-fMRI) is a promising non-invasive measurement of brain biomarkers to predict drug response in therapeutic development, the complexity of fMRI demands machine learning models with substantial capacity. However, extreme data scarcity in neuropathic pain research limits the application of high-capacity models. To address the challenge of data scarcity, we propose FMM$_{TC}$, a Foundation-Model-boosted Multimodal learning framework for fMRI-based neuropathic pain drug response prediction, which leverages both internal multimodal information in pain-specific data and external knowledge from large pain-agnostic data. Specifically, to maximize the value of limited pain-specific data, FMM$_{TC}$ integrates complementary information from two rs-fMRI modalities: Time series and functional Connectivity. FMM$_{TC}$ is further boosted by an fMRI foundation model with its external knowledge from extensive pain-agnostic fMRI datasets enriching limited pain-specific information. Evaluations with an in-house dataset and a public dataset from OpenNeuro demonstrate FMM$_{TC}$'s superior representation ability, generalizability, and cross-dataset adaptability over existing unimodal fMRI models that only consider one of the rs-fMRI modalities. The ablation study validates the effectiveness of multimodal learning and foundation-model-powered external knowledge transfer in FMM$_{TC}$. An integrated gradient-based interpretation study explains how FMM$_{TC}$'s cross-dataset dynamic behaviors enhance its adaptability. In conclusion, FMM$_{TC}$ boosts clinical trials in neuropathic pain therapeutic development by accurately predicting drug responses to improve the participant stratification efficiency.

Jie Wang, Yuji Liu, Binling Wang et al.

This paper describes the system developed by the XMUSPEECH team for the Multi-channel Multi-party Meeting Transcription Challenge (M2MeT). For the speaker diarization task, we propose a multi-channel speaker diarization system that obtains spatial information of speaker by Difference of Arrival (DOA) technology. Speaker-spatial embedding is generated by x-vector and s-vector derived from Filter-and-Sum Beamforming (FSB) which makes the embedding more robust. Specifically, we propose a novel multi-channel sequence-to-sequence neural network architecture named Discriminative Multi-stream Neural Network (DMSNet) which consists of Attention Filter-and-Sum block (AFSB) and Conformer encoder. We explore DMSNet to address overlapped speech problem on multi-channel audio. Compared with LSTM based OSD module, we achieve a decreases of 10.1% in Detection Error Rate(DetER). By performing DMSNet based OSD module, the DER of cluster-based diarization system decrease significantly form 13.44% to 7.63%. Our best fusion system achieves 7.09% and 9.80% of the diarization error rate (DER) on evaluation set and test set.