Weihong Chen

Shuo Jiang, Yuhao Hong, Chunbo Jiang et al.

Grounding radiology report descriptions to 3D CT volumes is essential for verifiable clinical interpretation, yet remains challenging due to the semantic-spatial gap between free-text narratives and volumetric anatomy. Existing report-assisted and vision-language grounding methods typically rely on phrase-level alignment or dense pixel supervision, resulting in limited lesion-wise correspondence and suboptimal localization accuracy. We propose GLeVE, a graph-guided lesion grounding framework with anatomical prior verification and octree-based autoregressive refinement. GLeVE treats each lesion description as an atomic semantic unit and encodes organ attribution, attributes, and inter-lesion relations through relation-aware graph reasoning to produce discriminative lesion-wise queries. Anatomy-aware proposal generation with region-level verification enforces one-to-one text-lesion alignment, while hierarchical octree refinement progressively improves boundary delineation. Experiments on AbdomenAtlas 3.0 demonstrate consistent gains over classical multimodal foundation models and report-supervised baselines in both segmentation accuracy and lesion-level localization.

Shenghao Zhu, Yifei Chen, Shuo Jiang et al.

Neurogliomas are among the most aggressive forms of cancer, presenting considerable challenges in both treatment and monitoring due to their unpredictable biological behavior. Magnetic resonance imaging (MRI) is currently the preferred method for diagnosing and monitoring gliomas. However, the lack of specific imaging techniques often compromises the accuracy of tumor segmentation during the imaging process. To address this issue, we introduce the XLSTM-HVED model. This model integrates a hetero-modal encoder-decoder framework with the Vision XLSTM module to reconstruct missing MRI modalities. By deeply fusing spatial and temporal features, it enhances tumor segmentation performance. The key innovation of our approach is the Self-Attention Variational Encoder (SAVE) module, which improves the integration of modal features. Additionally, it optimizes the interaction of features between segmentation and reconstruction tasks through the Squeeze-Fusion-Excitation Cross Awareness (SFECA) module. Our experiments using the BraTS 2024 dataset demonstrate that our model significantly outperforms existing advanced methods in handling cases where modalities are missing. Our source code is available at https://github.com/Quanato607/XLSTM-HVED.

Haoxin Yang, Weihong Chen, Xuemiao Xu et al.

Monocular 3D human pose estimation remains a challenging task due to inherent depth ambiguities and occlusions. Compared to traditional methods based on Transformers or Convolutional Neural Networks (CNNs), recent diffusion-based approaches have shown superior performance, leveraging their probabilistic nature and high-fidelity generation capabilities. However, these methods often fail to account for the spatial and temporal correlations across predicted frames, resulting in limited temporal consistency and inferior accuracy in predicted 3D pose sequences. To address these shortcomings, this paper proposes StarPose, an autoregressive diffusion framework that effectively incorporates historical 3D pose predictions and spatial-temporal physical guidance to significantly enhance both the accuracy and temporal coherence of pose predictions. Unlike existing approaches, StarPose models the 2D-to-3D pose mapping as an autoregressive diffusion process. By synergically integrating previously predicted 3D poses with 2D pose inputs via a Historical Pose Integration Module (HPIM), the framework generates rich and informative historical pose embeddings that guide subsequent denoising steps, ensuring temporally consistent predictions. In addition, a fully plug-and-play Spatial-Temporal Physical Guidance (STPG) mechanism is tailored to refine the denoising process in an iterative manner, which further enforces spatial anatomical plausibility and temporal motion dynamics, rendering robust and realistic pose estimates. Extensive experiments on benchmark datasets demonstrate that StarPose outperforms state-of-the-art methods, achieving superior accuracy and temporal consistency in 3D human pose estimation. Code is available at https://github.com/wileychan/StarPose.

Weihong Chen, Xuemiao Xu, Haoxin Yang et al.

Existing 3D Human Pose Estimation (HPE) methods achieve high accuracy but suffer from computational overhead and slow inference, while knowledge distillation methods fail to address spatial relationships between joints and temporal correlations in multi-frame inputs. In this paper, we propose Sparse Correlation and Joint Distillation (SCJD), a novel framework that balances efficiency and accuracy for 3D HPE. SCJD introduces Sparse Correlation Input Sequence Downsampling to reduce redundancy in student network inputs while preserving inter-frame correlations. For effective knowledge transfer, we propose Dynamic Joint Spatial Attention Distillation, which includes Dynamic Joint Embedding Distillation to enhance the student's feature representation using the teacher's multi-frame context feature, and Adjacent Joint Attention Distillation to improve the student network's focus on adjacent joint relationships for better spatial understanding. Additionally, Temporal Consistency Distillation aligns the temporal correlations between teacher and student networks through upsampling and global supervision. Extensive experiments demonstrate that SCJD achieves state-of-the-art performance. Code is available at https://github.com/wileychan/SCJD.

Shenghao Zhu, Yifei Chen, Weihong Chen et al.

Accurate and reliable brain tumor segmentation, particularly when dealing with missing modalities, remains a critical challenge in medical image analysis. Previous studies have not fully resolved the challenges of tumor boundary segmentation insensitivity and feature transfer in the absence of key imaging modalities. In this study, we introduce MST-KDNet, aimed at addressing these critical issues. Our model features Multi-Scale Transformer Knowledge Distillation to effectively capture attention weights at various resolutions, Dual-Mode Logit Distillation to improve the transfer of knowledge, and a Global Style Matching Module that integrates feature matching with adversarial learning. Comprehensive experiments conducted on the BraTS and FeTS 2024 datasets demonstrate that MST-KDNet surpasses current leading methods in both Dice and HD95 scores, particularly in conditions with substantial modality loss. Our approach shows exceptional robustness and generalization potential, making it a promising candidate for real-world clinical applications. Our source code is available at https://github.com/Quanato607/MST-KDNet.

Shenghao Zhu, Yifei Chen, Weihong Chen et al.

Accurate brain tumor segmentation is essential for preoperative evaluation and personalized treatment. Multi-modal MRI is widely used due to its ability to capture complementary tumor features across different sequences. However, in clinical practice, missing modalities are common, limiting the robustness and generalizability of existing deep learning methods that rely on complete inputs, especially under non-dominant modality combinations. To address this, we propose AdaMM, a multi-modal brain tumor segmentation framework tailored for missing-modality scenarios, centered on knowledge distillation and composed of three synergistic modules. The Graph-guided Adaptive Refinement Module explicitly models semantic associations between generalizable and modality-specific features, enhancing adaptability to modality absence. The Bi-Bottleneck Distillation Module transfers structural and textural knowledge from teacher to student models via global style matching and adversarial feature alignment. The Lesion-Presence-Guided Reliability Module predicts prior probabilities of lesion types through an auxiliary classification task, effectively suppressing false positives under incomplete inputs. Extensive experiments on the BraTS 2018 and 2024 datasets demonstrate that AdaMM consistently outperforms existing methods, exhibiting superior segmentation accuracy and robustness, particularly in single-modality and weak-modality configurations. In addition, we conduct a systematic evaluation of six categories of missing-modality strategies, confirming the superiority of knowledge distillation and offering practical guidance for method selection and future research. Our source code is available at https://github.com/Quanato607/AdaMM.

Dayong Liu, Chao Xu, Weihong Chen et al.

Multimodal Large Language Models (MLLMs) show promising results as decision-making engines for embodied agents operating in complex, physical environments. However, existing benchmarks often prioritize high-level planning or spatial reasoning, leaving the fine-grained action intelligence required for embodied physical interaction underexplored. To address this gap, we introduce CFG-Bench, a new benchmark designed to systematically evaluate this crucial capability. CFG-Bench consists of 1,368 curated videos paired with 19,562 three-modalities question-answer pairs targeting four cognitive abilities: 1) Physical Interaction, 2) Temporal-Causal Relation, 3) Intentional Understanding, and 4) Evaluative Judgment. Together, these dimensions provide a systematic framework for assessing a model's ability to translate visual observations into actionable knowledge, moving beyond mere surface-level recognition. Our comprehensive evaluation on CFG-Bench reveals that leading MLLMs struggle to produce detailed instructions for physical interactions and exhibit profound limitations in the higher-order reasoning of intention and evaluation. Moreover, supervised fine-tuning (SFT) on our data demonstrates that teaching an MLLMs to articulate fine-grained actions directly translates to significant performance gains on established embodied benchmarks. Our analysis highlights these limitations and offers insights for developing more capable and grounded embodied agents. Project page: \href{https://cfg-bench.github.io/}{https://cfg-bench.github.io/}.