Mira Rizkallah

Oriane Thiery, Mira Rizkallah, Clément Bailly et al.

Diffuse Large B-cell Lymphoma (DLBCL) is a lymphatic cancer involving one or more lymph nodes and extranodal sites. Its diagnostic and follow-up rely on Positron Emission Tomography (PET) and Computed Tomography (CT). After diagnosis, the number of nonresponding patients to standard front-line therapy remains significant (30-40%). This work aims to develop a computer-aided approach to identify high-risk patients requiring adapted treatment by efficiently exploiting all the information available for each patient, including both clinical and image data. We propose a method based on recent graph neural networks that combine imaging information from multiple lesions, and a cross-attention module to integrate different data modalities efficiently. The model is trained and evaluated on a private prospective multicentric dataset of 583 patients. Experimental results show that our proposed method outperforms classical supervised methods based on either clinical, imaging or both clinical and imaging data for the 2-year progression-free survival (PFS) classification accuracy.

Mira Rizkallah, Thomas Maugey, Christine Guillemot

Graph-based transforms have been shown to be powerful tools in terms of image energy compaction. However, when the support increases to best capture signal dependencies, the computation of the basis functions becomes rapidly untractable. This problem is in particular compelling for high dimensional imaging data such as light fields. The use of local transforms with limited supports is a way to cope with this computational difficulty. Unfortunately, the locality of the support may not allow us to fully exploit long term signal dependencies present in both the spatial and angular dimensions in the case of light fields. This paper describes sampling and prediction schemes with local graph-based transforms enabling to efficiently compact the signal energy and exploit dependencies beyond the local graph support. The proposed approach is investigated and is shown to be very efficient in the context of spatio-angular transforms for quasi-lossless compression of light fields.