Zheng Shen

Kanya Mo, Shen Zheng, Xiwei Wang et al.

The fully connected (FC) layer, one of the most fundamental modules in artificial neural networks (ANN), is often considered difficult and inefficient to train due to issues including the risk of overfitting caused by its large amount of parameters. Based on previous work studying ANN from linear spline perspectives, we propose a spline-based approach that eases the difficulty of training FC layers. Given some dataset, we first obtain a continuous piece-wise linear (CPWL) fit through spline methods such as multivariate adaptive regression spline (MARS). Next, we construct an ANN model from the linear spline model and continue to train the ANN model on the dataset using gradient descent optimization algorithms. Our experimental results and theoretical analysis show that our approach reduces the computational cost, accelerates the convergence of FC layers, and significantly increases the interpretability of the resulting model (FC layers) compared with standard ANN training with random parameter initialization followed by gradient descent optimizations.

Cheng Bian, Xin Yang, Jianqiang Ma et al.

Accurately segmenting left atrium in MR volume can benefit the ablation procedure of atrial fibrillation. Traditional automated solutions often fail in relieving experts from the labor-intensive manual labeling. In this paper, we propose a deep neural network based solution for automated left atrium segmentation in gadolinium-enhanced MR volumes with promising performance. We firstly argue that, for this volumetric segmentation task, networks in 2D fashion can present great superiorities in time efficiency and segmentation accuracy than networks with 3D fashion. Considering the highly varying shape of atrium and the branchy structure of associated pulmonary veins, we propose to adopt a pyramid module to collect semantic cues in feature maps from multiple scales for fine-grained segmentation. Also, to promote our network in classifying the hard examples, we propose an Online Hard Negative Example Mining strategy to identify voxels in slices with low classification certainties and penalize the wrong predictions on them. Finally, we devise a competitive training scheme to further boost the generalization ability of networks. Extensively verified on 20 testing volumes, our proposed framework achieves an average Dice of 92.83% in segmenting the left atria and pulmonary veins.