Abdulrhman Aljouie

Mohammed Baharoon, Hessa Almatar, Reema Alduhayan et al.

In recent years, deep learning has shown promise in predicting hypertension (HTN) from fundus images. However, most prior research has primarily focused on analyzing a single type of data, which may not capture the full complexity of HTN risk. To address this limitation, this study introduces a multimodal deep learning (MMDL) system, dubbed HyMNet, which combines fundus images and cardiometabolic risk factors, specifically age and gender, to improve hypertension detection capabilities. Our MMDL system uses RETFound, a foundation model pre-trained on 1.6 million retinal images, for the fundus path and a fully connected neural network for the age and gender path. The two paths are jointly trained by concatenating the feature vectors from each path that are then fed into a fusion network. The system was trained on 5,016 retinal images from 1,243 individuals collected from the Saudi Ministry of National Guard Health Affairs. The results show that the multimodal model that integrates fundus images along with age and gender outperforms the unimodal system trained solely on fundus photographs, with an F1 score of 0.771 [0.747, 0.796], and 0.745 [0.719, 0.772] for hypertension detection, respectively. Additionally, we studied the effect underlying diabetes mellitus has on the model's predictive ability, concluding that diabetes is used as a confounding variable for distinguishing hypertensive cases. Our code and model weights are publicly available at https://github.com/MohammedSB/HyMNet.

Cengiz Ozel, Waleed Nadeem, Samuel Potter et al.

Post-traumatic stress disorder (PTSD) is highly prevalent yet chronically underreported among combat-exposed military personnel. This paper presents Molhim, a culturally adapted multimodal conversational AI platform that supports purpose-specific interactions through a configurable conversational pipeline consisting of session setup, real-time dialogue with a high-fidelity virtual avatar, and post-session analysis and feedback. In this work, we examine the PTSD screening configuration of the Molhim platform in a military healthcare context. The system employs a conversational avatar driven by a large language model, integrating real-time speech recognition, visual understanding of user input, text-to-speech synthesis, and a high-fidelity human avatar to support structured multi-turn dialogue and automated post-session analysis, including administration of the PTSD Checklist for DSM-5 (PCL-5). These findings suggest the feasibility of Molhim as a conversational platform for PTSD screening and highlight design considerations for socially cooperative human-AI systems in clinical environments.

Asif Azad, MD Sadik Hossain Shanto, Mohammad Sadat Hossain et al.

Automated phoneme-level pronunciation assessment is vital for scalable speech therapy and language learning, yet validated tools for Arabic remain scarce. We present Harf-Speech, a modular system scoring Arabic pronunciation at the phoneme level on a clinical scale. It combines an MSA phonetizer, a fine-tuned speech-to-phoneme model, Levenshtein alignment, and a blended scorer using longest common subsequence and edit-distance metrics. We fine-tune three ASR architectures on Arabic phoneme data and benchmark them with zero-shot multimodal models; the best, OmniASR-CTC-1B-v2, achieves 8.92\% phoneme error rate. Three certified speech-language pathologists independently scored 40 utterances for clinical validation. Harf-Speech attains a Pearson correlation of 0.791 and ICC(2,1) of 0.659 with mean expert scores, outperforming existing end-to-end assessment frameworks. These results show Harf-Speech yields clinically aligned, interpretable scores comparable to inter-rater expert agreement.

Mohammed Baharoon, Waseem Qureshi, Jiahong Ouyang et al.

The integration of deep learning systems into healthcare has been hindered by the resource-intensive process of data annotation and the inability of these systems to generalize to different data distributions. Foundation models, which are models pre-trained on large datasets, have emerged as a solution to reduce reliance on annotated data and enhance model generalizability and robustness. DINOv2 is an open-source foundation model pre-trained with self-supervised learning on 142 million curated natural images that exhibits promising capabilities across various vision tasks. Nevertheless, a critical question remains unanswered regarding DINOv2's adaptability to radiological imaging, and whether its features are sufficiently general to benefit radiology image analysis. Therefore, this study comprehensively evaluates the performance DINOv2 for radiology, conducting over 200 evaluations across diverse modalities (X-ray, CT, and MRI). To measure the effectiveness and generalizability of DINOv2's feature representations, we analyze the model across medical image analysis tasks including disease classification and organ segmentation on both 2D and 3D images, and under different settings like kNN, few-shot learning, linear-probing, end-to-end fine-tuning, and parameter-efficient fine-tuning. Comparative analyses with established supervised, self-supervised, and weakly-supervised models reveal DINOv2's superior performance and cross-task generalizability. The findings contribute insights to potential avenues for optimizing pre-training strategies for medical imaging and enhancing the broader understanding of DINOv2's role in bridging the gap between natural and radiological image analysis. Our code is available at https://github.com/MohammedSB/DINOv2ForRadiology

Mohammed Baharoon, Siavash Raissi, John S. Jun et al.

We introduce RadGame, an AI-powered gamified platform for radiology education that targets two core skills: localizing findings and generating reports. Traditional radiology training is based on passive exposure to cases or active practice with real-time input from supervising radiologists, limiting opportunities for immediate and scalable feedback. RadGame addresses this gap by combining gamification with large-scale public datasets and automated, AI-driven feedback that provides clear, structured guidance to human learners. In RadGame Localize, players draw bounding boxes around abnormalities, which are automatically compared to radiologist-drawn annotations from public datasets, and visual explanations are generated by vision-language models for user missed findings. In RadGame Report, players compose findings given a chest X-ray, patient age and indication, and receive structured AI feedback based on radiology report generation metrics, highlighting errors and omissions compared to a radiologist's written ground truth report from public datasets, producing a final performance and style score. In a prospective evaluation, participants using RadGame achieved a 68% improvement in localization accuracy compared to 17% with traditional passive methods and a 31% improvement in report-writing accuracy compared to 4% with traditional methods after seeing the same cases. RadGame highlights the potential of AI-driven gamification to deliver scalable, feedback-rich radiology training and reimagines the application of medical AI resources in education.