Mohsen Khadem

Salvatore Esposito, Matías Mattamala, Daniel Rebain et al.

Continuum robots are advancing bronchoscopy procedures by accessing complex lung airways and enabling targeted interventions. However, their development is limited by the lack of realistic training and test environments: Real data is difficult to collect due to ethical constraints and patient safety concerns, and developing autonomy algorithms requires realistic imaging and physical feedback. We present ROOM (Realistic Optical Observation in Medicine), a comprehensive simulation framework designed for generating photorealistic bronchoscopy training data. By leveraging patient CT scans, our pipeline renders multi-modal sensor data including RGB images with realistic noise and light specularities, metric depth maps, surface normals, optical flow and point clouds at medically relevant scales. We validate the data generated by ROOM in two canonical tasks for medical robotics: multi-view pose estimation and monocular depth estimation, demonstrating diverse challenges that state-of-the-art methods must overcome to transfer to these medical settings. Furthermore, we show that the data produced by ROOM can be used to fine-tune existing depth estimation models to overcome these challenges, also enabling other downstream applications such as navigation. We expect that ROOM will enable large-scale data generation across diverse patient anatomies and procedural scenarios that are challenging to capture in clinical settings. Code and data: https://github.com/iamsalvatore/room.

Yash Kulkarni, Mobina Tavangarifard, Daniyal Maroufi et al.

This paper introduces a novel shape-sensing approach for Concentric Tube Steerable Drilling Robots (CT-SDRs) based on Optical Frequency Domain Reflectometry (OFDR). Unlike traditional FBG-based methods, OFDR enables continuous strain measurement along the entire fiber length with enhanced spatial resolution. In the proposed method, a Shape Sensing Assembly (SSA) is first fabricated by integrating a single OFDR fiber with a flat NiTi wire. The calibrated SSA is then routed through and housed within the internal channel of a flexible drilling instrument, which is guided by the pre-shaped NiTi tube of the CT-SDR. In this configuration, the drilling instrument serves as a protective sheath for the SSA during drilling, eliminating the need for integration or adhesion to the instrument surface that is typical of conventional optical sensor approaches. The performance of the proposed SSA, integrated within the cannulated CT-SDR, was thoroughly evaluated under free-bending conditions and during drilling along multiple J-shaped trajectories in synthetic Sawbones phantoms. Results demonstrate accurate and reliable shape-sensing capability, confirming the feasibility and robustness of this integration strategy.

Francis Xiatian Zhang, Emile Mackute, Mohammadreza Kasaei et al.

Monocular depth estimation in bronchoscopy can significantly improve real-time navigation accuracy and enhance the safety of interventions in complex, branching airways. Recent advances in depth foundation models have shown promise for endoscopic scenarios, yet these models often lack anatomical awareness in bronchoscopy, overfitting to local textures rather than capturing the global airway structure, particularly under ambiguous depth cues and poor lighting. To address this, we propose Brea-Depth, a novel framework that integrates airway-specific geometric priors into foundation model adaptation for bronchoscopic depth estimation. Our method introduces a depth-aware CycleGAN, refining the translation between real bronchoscopic images and airway geometries from anatomical data, effectively bridging the domain gap. In addition, we introduce an airway structure awareness loss to enforce depth consistency within the airway lumen while preserving smooth transitions and structural integrity. By incorporating anatomical priors, Brea-Depth enhances model generalization and yields more robust, accurate 3D airway reconstructions. To assess anatomical realism, we introduce Airway Depth Structure Evaluation, a new metric for structural consistency. We validate BREA-Depth on a collected ex vivo human lung dataset and an open bronchoscopic dataset, where it outperforms existing methods in anatomical depth preservation.