Jin Fan

Zhaojie Fang, Shenghao Zhu, Yifei Chen et al.

Alzheimer's Disease (AD) is a progressive, irreversible neurodegenerative disorder that often originates from Mild Cognitive Impairment (MCI). This progression results in significant memory loss and severely affects patients' quality of life. Clinical trials have consistently shown that early and targeted interventions for individuals with MCI may slow or even prevent the advancement of AD. Research indicates that accurate medical classification requires diverse multimodal data, including detailed assessment scales and neuroimaging techniques like Magnetic Resonance Imaging (MRI) and Positron Emission Tomography (PET). However, simultaneously collecting the aforementioned three modalities for training presents substantial challenges. To tackle these difficulties, we propose GFE-Mamba, a multimodal classifier founded on Generative Feature Extractor. The intermediate features provided by this Extractor can compensate for the shortcomings of PET and achieve profound multimodal fusion in the classifier. The Mamba block, as the backbone of the classifier, enables it to efficiently extract information from long-sequence scale information. Pixel-level Bi-cross Attention supplements pixel-level information from MRI and PET. We provide our rationale for developing this cross-temporal progression prediction dataset and the pre-trained Extractor weights. Our experimental findings reveal that the GFE-Mamba model effectively predicts the progression from MCI to AD and surpasses several leading methods in the field. Our source code is available at https://github.com/Tinysqua/GFE-Mamba.

Ke Zhang, Jin Fan, Shaoli Huang et al.

Data augmentation has been proved effective in training deep models. Existing data augmentation methods tackle the fine-grained problem by blending image pairs and fusing corresponding labels according to the statistics of mixed pixels, which produces additional noise harmful to the performance of networks. Motivated by this, we present a simple yet effective cross ensemble knowledge distillation (CEKD) model for fine-grained feature learning. We innovatively propose a cross distillation module to provide additional supervision to alleviate the noise problem, and propose a collaborative ensemble module to overcome the target conflict problem. The proposed model can be trained in an end-to-end manner, and only requires image-level label supervision. Extensive experiments on widely used fine-grained benchmarks demonstrate the effectiveness of our proposed model. Specifically, with the backbone of ResNet-101, CEKD obtains the accuracy of 89.59%, 95.96% and 94.56% in three datasets respectively, outperforming state-of-the-art API-Net by 0.99%, 1.06% and 1.16%.