Yike Li

Shunxing Bao, Sichen Zhu, Vasantha L Kolachala et al.

Crohn's disease (CD) is a chronic and relapsing inflammatory condition that affects segments of the gastrointestinal tract. CD activity is determined by histological findings, particularly the density of neutrophils observed on Hematoxylin and Eosin stains (H&E) imaging. However, understanding the broader morphometry and local cell arrangement beyond cell counting and tissue morphology remains challenging. To address this, we characterize six distinct cell types from H&E images and develop a novel approach for the local spatial signature of each cell. Specifically, we create a 10-cell neighborhood matrix, representing neighboring cell arrangements for each individual cell. Utilizing t-SNE for non-linear spatial projection in scatter-plot and Kernel Density Estimation contour-plot formats, our study examines patterns of differences in the cellular environment associated with the odds ratio of spatial patterns between active CD and control groups. This analysis is based on data collected at the two research institutes. The findings reveal heterogeneous nearest-neighbor patterns, signifying distinct tendencies of cell clustering, with a particular focus on the rectum region. These variations underscore the impact of data heterogeneity on cell spatial arrangements in CD patients. Moreover, the spatial distribution disparities between the two research sites highlight the significance of collaborative efforts among healthcare organizations. All research analysis pipeline tools are available at https://github.com/MASILab/cellNN.

Xiaodong Guo, Tong Liu, Yike Li et al.

RGB-thermal (RGB-T) semantic segmentation improves the environmental perception of autonomous platforms in challenging conditions. Prevailing models employ encoders pre-trained on RGB images to extract features from both RGB and infrared inputs, and design additional modules to achieve cross-modal feature fusion. This results in limited thermal feature extraction and suboptimal cross-modal fusion, while the redundant encoders further compromises the model's real-time efficiency. To address the above issues, we propose TUNI, with an RGB-T encoder consisting of multiple stacked blocks that simultaneously perform multi-modal feature extraction and cross-modal fusion. By leveraging large-scale pre-training with RGB and pseudo-thermal data, the RGB-T encoder learns to integrate feature extraction and fusion in a unified manner. By slimming down the thermal branch, the encoder achieves a more compact architecture. Moreover, we introduce an RGB-T local module to strengthen the encoder's capacity for cross-modal local feature fusion. The RGB-T local module employs adaptive cosine similarity to selectively emphasize salient consistent and distinct local features across RGB-T modalities. Experimental results show that TUNI achieves competitive performance with state-of-the-art models on FMB, PST900 and CART, with fewer parameters and lower computational cost. Meanwhile, it achieves an inference speed of 27 FPS on a Jetson Orin NX, demonstrating its real-time capability in deployment. Codes are available at https://github.com/xiaodonguo/TUNI.

Yifan Liu, Yike Li, Dong Wang

Media bias significantly shapes public perception by reinforcing stereotypes and exacerbating societal divisions. Prior research has often focused on isolated media bias dimensions such as \textit{political bias} or \textit{racial bias}, neglecting the complex interrelationships among various bias dimensions across different topic domains. Moreover, we observe that models trained on existing media bias benchmarks fail to generalize effectively on recent social media posts, particularly in certain bias identification tasks. This shortfall primarily arises because these benchmarks do not adequately reflect the rapidly evolving nature of social media content, which is characterized by shifting user behaviors and emerging trends. In response to these limitations, our research introduces a novel dataset collected from YouTube and Reddit over the past five years. Our dataset includes automated annotations for YouTube content across a broad spectrum of bias dimensions, such as gender, racial, and political biases, as well as hate speech, among others. It spans diverse domains including politics, sports, healthcare, education, and entertainment, reflecting the complex interplay of biases across different societal sectors. Through comprehensive statistical analysis, we identify significant differences in bias expression patterns and intra-domain bias correlations across these domains. By utilizing our understanding of the correlations among various bias dimensions, we lay the groundwork for creating advanced systems capable of detecting multiple biases simultaneously. Overall, our dataset advances the field of media bias identification, contributing to the development of tools that promote fairer media consumption. The comprehensive awareness of existing media bias fosters more ethical journalism, promotes cultural sensitivity, and supports a more informed and equitable public discourse.

Andrew Chang, Yike Li, Iran R. Roman et al.

Audio DNNs have demonstrated impressive performance on various machine listening tasks; however, most of their representations are computationally costly and uninterpretable, leaving room for optimization. Here, we propose a novel approach centered on spectrotemporal modulation (STM) features, a signal processing method that mimics the neurophysiological representation in the human auditory cortex. The classification performance of our STM-based model, without any pretraining, is comparable to that of pretrained audio DNNs across diverse naturalistic speech, music, and environmental sounds, which are essential categories for both human cognition and machine perception. These results show that STM is an efficient and interpretable feature representation for audio classification, advancing the development of machine listening and unlocking exciting new possibilities for basic understanding of speech and auditory sciences, as well as developing audio BCI and cognitive computing.