Yasha Wang

Yinghao Zhu, Junyi Gao, Zixiang Wang et al.

Large Language Models (LLMs) are increasingly deployed in medicine. However, their utility in non-generative clinical prediction, often presumed inferior to specialized models, remains under-evaluated, leading to ongoing debate within the field and potential for misuse, misunderstanding, or over-reliance due to a lack of systematic benchmarking. Our ClinicRealm study addresses this by benchmarking 15 GPT-style LLMs, 5 BERT-style models, and 11 traditional methods on unstructured clinical notes and structured Electronic Health Records (EHR), while also assessing their reasoning, reliability, and fairness. Key findings reveal a significant shift: for clinical note predictions, leading LLMs (e.g., DeepSeek-V3.1-Think, GPT-5) in zero-shot settings now decisively outperform finetuned BERT models. On structured EHRs, while specialized models excel with ample data, advanced LLMs (e.g., GPT-5, DeepSeek-V3.1-Think) show potent zero-shot capabilities, often surpassing conventional models in data-scarce settings. Notably, leading open-source LLMs can match or exceed proprietary counterparts. These results provide compelling evidence that modern LLMs are competitive tools for non-generative clinical prediction, particularly with unstructured text and offering data-efficient structured data options, thus necessitating a re-evaluation of model selection strategies. This research should serve as an important insight for medical informaticists, AI developers, and clinical researchers, potentially prompting a reassessment of current assumptions and inspiring new approaches to LLM application in predictive healthcare.

Xinyu Ma, Yifeng Xu, Yang Lin et al.

We introduce DRESS, a novel approach for generating stylized large language model (LLM) responses through representation editing. Existing methods like prompting and fine-tuning are either insufficient for complex style adaptation or computationally expensive, particularly in tasks like NPC creation or character role-playing. Our approach leverages the over-parameterized nature of LLMs to disentangle a style-relevant subspace within the model's representation space to conduct representation editing, ensuring a minimal impact on the original semantics. By applying adaptive editing strengths, we dynamically adjust the steering vectors in the style subspace to maintain both stylistic fidelity and semantic integrity. We develop two stylized QA benchmark datasets to validate the effectiveness of DRESS, and the results demonstrate significant improvements compared to baseline methods such as prompting and ITI. In short, DRESS is a lightweight, train-free solution for enhancing LLMs with flexible and effective style control, making it particularly useful for developing stylized conversational agents. Codes and benchmark datasets are available at https://github.com/ArthurLeoM/DRESS-LLM.

Yujie Feng, Liming Zhan, Zexin Lu et al.

Regular updates are essential for maintaining up-to-date knowledge in large language models (LLMs). Consequently, various model editing methods have been developed to update specific knowledge within LLMs. However, training-based approaches often struggle to effectively incorporate new knowledge while preserving unrelated general knowledge. To address this challenge, we propose a novel framework called Geometric Knowledge Editing (GeoEdit). GeoEdit utilizes the geometric relationships of parameter updates from fine-tuning to differentiate between neurons associated with new knowledge updates and those related to general knowledge perturbations. By employing a direction-aware knowledge identification method, we avoid updating neurons with directions approximately orthogonal to existing knowledge, thus preserving the model's generalization ability. For the remaining neurons, we integrate both old and new knowledge for aligned directions and apply a "forget-then-learn" editing strategy for opposite directions. Additionally, we introduce an importance-guided task vector fusion technique that filters out redundant information and provides adaptive neuron-level weighting, further enhancing model editing performance. Extensive experiments on two publicly available datasets demonstrate the superiority of GeoEdit over existing state-of-the-art methods.