Matthias Jung

AR
h-index23
3papers
Novelty35%
AI Score38

3 Papers

IVSep 10, 2025Code
RoentMod: A Synthetic Chest X-Ray Modification Model to Identify and Correct Image Interpretation Model Shortcuts

Lauren H. Cooke, Matthias Jung, Jan M. Brendel et al.

Chest radiographs (CXRs) are among the most common tests in medicine. Automated image interpretation may reduce radiologists\' workload and expand access to diagnostic expertise. Deep learning multi-task and foundation models have shown strong performance for CXR interpretation but are vulnerable to shortcut learning, where models rely on spurious and off-target correlations rather than clinically relevant features to make decisions. We introduce RoentMod, a counterfactual image editing framework that generates anatomically realistic CXRs with user-specified, synthetic pathology while preserving unrelated anatomical features of the original scan. RoentMod combines an open-source medical image generator (RoentGen) with an image-to-image modification model without requiring retraining. In reader studies with board-certified radiologists and radiology residents, RoentMod-produced images appeared realistic in 93\% of cases, correctly incorporated the specified finding in 89-99\% of cases, and preserved native anatomy comparable to real follow-up CXRs. Using RoentMod, we demonstrate that state-of-the-art multi-task and foundation models frequently exploit off-target pathology as shortcuts, limiting their specificity. Incorporating RoentMod-generated counterfactual images during training mitigated this vulnerability, improving model discrimination across multiple pathologies by 3-19\% AUC in internal validation and by 1-11\% for 5 out of 6 tested pathologies in external testing. These findings establish RoentMod as a broadly applicable tool for probing and correcting shortcut learning in medical AI. By enabling controlled counterfactual interventions, RoentMod enhances the robustness and interpretability of CXR interpretation models and provides a generalizable strategy for improving foundation models in medical imaging.

57.4ARApr 30
Autoformalizing Memory Specifications with Agents

Jan Ole Ernst, Dmitri Michelangelo Saberi, Derek Christ et al.

The primary goal of Design Verification (DV) is to ensure that a proposed chip design implementation (either in code, or physical form) exactly matches its specification and is free of functional errors in order to avoid costly re-designs. Achieving this often demands extensive manual interpretation, translating the specification document into a formal, testable representation. While AI has made progress in DV, current approaches typically focus on narrow, isolated tasks rather than full end-to-end specification compliance of modern chip designs, failing to capture the complexity of real-world verification. Our method automatically formalizes natural language memory chip specifications, for industry relevant Dynamic Random Access Memory (DRAM) standards, into a formal representation called DRAMPyML that can be used for downstream DV tasks like the generation of SystemVerilog assertions, stimulus, and functional coverage. We also release our benchmarking dataset, DRAMBench, which can be used to evaluate the evolution of model capabilities (and new approaches) at hardware autoformalization.

LGJul 24, 2018
Deep-CLASS at ISIC Machine Learning Challenge 2018

Sara Nasiri, Matthias Jung, Julien Helsper et al.

This paper reports the method and evaluation results of MedAusbild team for ISIC challenge task. Since early 2017, our team has worked on melanoma classification [1][6], and has employed deep learning since beginning of 2018 [7]. Deep learning helps researchers absolutely to treat and detect diseases by analyzing medical data (e.g., medical images). One of the representative models among the various deep-learning models is a convolutional neural network (CNN). Although our team has an experience with segmentation and classification of benign and malignant skin-lesions, we have participated in the task 3 of ISIC Challenge 2018 for classification of seven skin diseases, explained in this paper.