Natural Language Processing Methods to Identify Oncology Patients at High Risk for Acute Care with Clinical NotesClaudio Fanconi, Marieke van Buchem, Tina Hernandez-Boussard
Clinical notes are an essential component of a health record. This paper evaluates how natural language processing (NLP) can be used to identify the risk of acute care use (ACU) in oncology patients, once chemotherapy starts. Risk prediction using structured health data (SHD) is now standard, but predictions using free-text formats are complex. This paper explores the use of free-text notes for the prediction of ACU instead of SHD. Deep Learning models were compared to manually engineered language features. Results show that SHD models minimally outperform NLP models; an l1-penalised logistic regression with SHD achieved a C-statistic of 0.748 (95%-CI: 0.735, 0.762), while the same model with language features achieved 0.730 (95%-CI: 0.717, 0.745) and a transformer-based model achieved 0.702 (95%-CI: 0.688, 0.717). This paper shows how language models can be used in clinical applications and underlines how risk bias is different for diverse patient groups, even using only free-text data.
Unveiling and Mitigating Bias in Mental Health Analysis with Large Language ModelsYuqing Wang, Yun Zhao, Sara Alessandra Keller et al.
The advancement of large language models (LLMs) has demonstrated strong capabilities across various applications, including mental health analysis. However, existing studies have focused on predictive performance, leaving the critical issue of fairness underexplored, posing significant risks to vulnerable populations. Despite acknowledging potential biases, previous works have lacked thorough investigations into these biases and their impacts. To address this gap, we systematically evaluate biases across seven social factors (e.g., gender, age, religion) using ten LLMs with different prompting methods on eight diverse mental health datasets. Our results show that GPT-4 achieves the best overall balance in performance and fairness among LLMs, although it still lags behind domain-specific models like MentalRoBERTa in some cases. Additionally, our tailored fairness-aware prompts can effectively mitigate bias in mental health predictions, highlighting the great potential for fair analysis in this field.