Shuxin Li

Pengdeng Li, Xinrun Wang, Shuxin Li et al.

In this work, we attempt to bridge the two fields of finite-agent and infinite-agent games, by studying how the optimal policies of agents evolve with the number of agents (population size) in mean-field games, an agent-centric perspective in contrast to the existing works focusing typically on the convergence of the empirical distribution of the population. To this end, the premise is to obtain the optimal policies of a set of finite-agent games with different population sizes. However, either deriving the closed-form solution for each game is theoretically intractable, training a distinct policy for each game is computationally intensive, or directly applying the policy trained in a game to other games is sub-optimal. We address these challenges through the Population-size-Aware Policy Optimization (PAPO). Our contributions are three-fold. First, to efficiently generate efficient policies for games with different population sizes, we propose PAPO, which unifies two natural options (augmentation and hypernetwork) and achieves significantly better performance. PAPO consists of three components: i) the population-size encoding which transforms the original value of population size to an equivalent encoding to avoid training collapse, ii) a hypernetwork to generate a distinct policy for each game conditioned on the population size, and iii) the population size as an additional input to the generated policy. Next, we construct a multi-task-based training procedure to efficiently train the neural networks of PAPO by sampling data from multiple games with different population sizes. Finally, extensive experiments on multiple environments show the significant superiority of PAPO over baselines, and the analysis of the evolution of the generated policies further deepens our understanding of the two fields of finite-agent and infinite-agent games.

Shuxin Li, Xinrun Wang, Youzhi Zhang et al.

Offline reinforcement learning (offline RL) is an emerging field that has recently begun gaining attention across various application domains due to its ability to learn strategies from earlier collected datasets. Offline RL proved very successful, paving a path to solving previously intractable real-world problems, and we aim to generalize this paradigm to a multiplayer-game setting. To this end, we introduce a problem of offline equilibrium finding (OEF) and construct multiple types of datasets across a wide range of games using several established methods. To solve the OEF problem, we design a model-based framework that can directly apply any online equilibrium finding algorithm to the OEF setting while making minimal changes. The three most prominent contemporary online equilibrium finding algorithms are adapted to the context of OEF, creating three model-based variants: OEF-PSRO and OEF-CFR, which generalize the widely-used algorithms PSRO and Deep CFR to compute Nash equilibria (NEs), and OEF-JPSRO, which generalizes the JPSRO to calculate (Coarse) Correlated equilibria ((C)CEs). We also combine the behavior cloning policy with the model-based policy to further improve the performance and provide a theoretical guarantee of the solution quality. Extensive experimental results demonstrate the superiority of our approach over offline RL algorithms and the importance of using model-based methods for OEF problems. We hope our work will contribute to advancing research in large-scale equilibrium finding.

Chong Wang, Mengyao Li, Junjun He et al.

Recent breakthroughs in large language models (LLMs) offer unprecedented natural language understanding and generation capabilities. However, existing surveys on LLMs in biomedicine often focus on specific applications or model architectures, lacking a comprehensive analysis that integrates the latest advancements across various biomedical domains. This review, based on an analysis of 484 publications sourced from databases including PubMed, Web of Science, and arXiv, provides an in-depth examination of the current landscape, applications, challenges, and prospects of LLMs in biomedicine, distinguishing itself by focusing on the practical implications of these models in real-world biomedical contexts. Firstly, we explore the capabilities of LLMs in zero-shot learning across a broad spectrum of biomedical tasks, including diagnostic assistance, drug discovery, and personalized medicine, among others, with insights drawn from 137 key studies. Then, we discuss adaptation strategies of LLMs, including fine-tuning methods for both uni-modal and multi-modal LLMs to enhance their performance in specialized biomedical contexts where zero-shot fails to achieve, such as medical question answering and efficient processing of biomedical literature. Finally, we discuss the challenges that LLMs face in the biomedicine domain including data privacy concerns, limited model interpretability, issues with dataset quality, and ethics due to the sensitive nature of biomedical data, the need for highly reliable model outputs, and the ethical implications of deploying AI in healthcare. To address these challenges, we also identify future research directions of LLM in biomedicine including federated learning methods to preserve data privacy and integrating explainable AI methodologies to enhance the transparency of LLMs.

Shuxin Li, Chang Yang, Youzhi Zhang et al.

Nash equilibrium (NE) is a widely adopted solution concept in game theory due to its stability property. However, we observe that the NE strategy might not always yield the best results, especially against opponents who do not adhere to NE strategies. Based on this observation, we pose a new game-solving question: Can we learn a model that can exploit any, even NE, opponent to maximize their own utility? In this work, we make the first attempt to investigate this problem through in-context learning. Specifically, we introduce a novel method, In-Context Exploiter (ICE), to train a single model that can act as any player in the game and adaptively exploit opponents entirely by in-context learning. Our ICE algorithm involves generating diverse opponent strategies, collecting interactive history training data by a reinforcement learning algorithm, and training a transformer-based agent within a well-designed curriculum learning framework. Finally, comprehensive experimental results validate the effectiveness of our ICE algorithm, showcasing its in-context learning ability to exploit any unknown opponent, thereby positively answering our initial game-solving question.

Shuxin Zhuang, Shuxin Li, Tianji Yang et al.

After the great achievement of solving two-player zero-sum games, more and more AI researchers focus on solving multiplayer games. To facilitate the development of designing efficient learning algorithms for solving multiplayer games, we propose a multiplayer game platform for solving Urban Network Security Games (\textbf{UNSG}) that model real-world scenarios. That is, preventing criminal activity is a highly significant responsibility assigned to police officers in cities, and police officers have to allocate their limited security resources to interdict the escaping criminal when a crime takes place in a city. This interaction between multiple police officers and the escaping criminal can be modeled as a UNSG. The variants of UNSGs can model different real-world settings, e.g., whether real-time information is available or not, and whether police officers can communicate or not. The main challenges of solving this game include the large size of the game and the co-existence of cooperation and competition. While previous efforts have been made to tackle UNSGs, they have been hampered by performance and scalability issues. Therefore, we propose an open-source UNSG platform (\textbf{GraphChase}) for designing efficient learning algorithms for solving UNSGs. Specifically, GraphChase offers a unified and flexible game environment for modeling various variants of UNSGs, supporting the development, testing, and benchmarking of algorithms. We believe that GraphChase not only facilitates the development of efficient algorithms for solving real-world problems but also paves the way for significant advancements in algorithmic development for solving general multiplayer games.

Renyang Liu, Jiale Li, Jie Zhang et al.

Palmprint recognition is deployed in security-critical applications, including access control and palm-based payment, due to its contactless acquisition and highly discriminative ridge-and-crease textures. However, the robustness of deep palmprint recognition systems against physically realizable attacks remains insufficiently understood. Existing studies are largely confined to the digital setting and do not adequately account for the texture-dominant nature of palmprint recognition or the distortions introduced during physical acquisition. To address this gap, we propose CAAP, a capture-aware adversarial patch framework for palmprint recognition. CAAP learns a universal patch that can be reused across inputs while remaining effective under realistic acquisition variation. To match the structural characteristics of palmprints, the framework adopts a cross-shaped patch topology, which enlarges spatial coverage under a fixed pixel budget and more effectively disrupts long-range texture continuity. CAAP further integrates three modules: ASIT for input-conditioned patch rendering, RaS for stochastic capture-aware simulation, and MS-DIFE for feature-level identity-disruptive guidance. We evaluate CAAP on the Tongji, IITD, and AISEC datasets against generic CNN backbones and palmprint-specific recognition models. Experiments show that CAAP achieves strong untargeted and targeted attack performance with favorable cross-model and cross-dataset transferability. The results further show that, although adversarial training can partially reduce the attack success rate, substantial residual vulnerability remains. These findings indicate that deep palmprint recognition systems remain vulnerable to physically realizable, capture-aware adversarial patch attacks, underscoring the need for more effective defenses in practice. Code available at https://github.com/ryliu68/CAAP.

Shuxin Zhuang, Linjian Meng, Shuxin Li et al.

Urban Network Security Games (UNSGs), which model the strategic allocation of limited security resources on city road networks, are critical for urban safety. However, finding a Nash Equilibrium (NE) in large-scale UNSGs is challenging due to their massive and combinatorial action spaces. One common approach to addressing these games is the Policy-Space Response Oracle (PSRO) framework, which requires computing best responses (BR) at each iteration. However, precisely computing exact BRs is impractical in large-scale games, and employing reinforcement learning to approximate BRs inevitably introduces errors, which limits the overall effectiveness of the PSRO methods. Recent advancements in leveraging non-convex stochastic optimization to approximate an NE offer a promising alternative to the burdensome BR computation. However, utilizing existing stochastic optimization techniques with an unbiased loss function for UNSGs remains challenging because the action spaces are too vast to be effectively represented by neural networks. To address these issues, we introduce Tree-based Stochastic Optimization (TSO), a framework that bridges the gap between the stochastic optimization paradigm for NE-finding and the demands of UNSGs. Specifically, we employ the tree-based action representation that maps the whole action space onto a tree structure, addressing the challenge faced by neural networks in representing actions when the action space cannot be enumerated. We then incorporate this representation into the loss function and theoretically demonstrate its equivalence to the unbiased loss function. To further enhance the quality of the converged solution, we introduce a sample-and-prune mechanism that reduces the risk of being trapped in suboptimal local optima. Extensive experimental results indicate the superiority of TSO over other baseline algorithms in addressing the UNSGs.

Pengdeng Li, Shuxin Li, Xinrun Wang et al.

Pursuit-evasion games (PEGs) model interactions between a team of pursuers and an evader in graph-based environments such as urban street networks. Recent advancements have demonstrated the effectiveness of the pre-training and fine-tuning paradigm in PSRO to improve scalability in solving large-scale PEGs. However, these methods primarily focus on specific PEGs with fixed initial conditions that may vary substantially in real-world scenarios, which significantly hinders the applicability of the traditional methods. To address this issue, we introduce Grasper, a GeneRAlist purSuer for Pursuit-Evasion pRoblems, capable of efficiently generating pursuer policies tailored to specific PEGs. Our contributions are threefold: First, we present a novel architecture that offers high-quality solutions for diverse PEGs, comprising critical components such as (i) a graph neural network (GNN) to encode PEGs into hidden vectors, and (ii) a hypernetwork to generate pursuer policies based on these hidden vectors. As a second contribution, we develop an efficient three-stage training method involving (i) a pre-pretraining stage for learning robust PEG representations through self-supervised graph learning techniques like GraphMAE, (ii) a pre-training stage utilizing heuristic-guided multi-task pre-training (HMP) where heuristic-derived reference policies (e.g., through Dijkstra's algorithm) regularize pursuer policies, and (iii) a fine-tuning stage that employs PSRO to generate pursuer policies on designated PEGs. Finally, we perform extensive experiments on synthetic and real-world maps, showcasing Grasper's significant superiority over baselines in terms of solution quality and generalizability. We demonstrate that Grasper provides a versatile approach for solving pursuit-evasion problems across a broad range of scenarios, enabling practical deployment in real-world situations.

Chang Yang, Ruiyu Wang, Junzhe Jiang et al.

Reasoning is the fundamental capability of large language models (LLMs). Due to the rapid progress of LLMs, there are two main issues of current benchmarks: i) these benchmarks can be crushed in a short time (less than 1 year), and ii) these benchmarks may be easily hacked. To handle these issues, we propose the ever-scalingness for building the benchmarks which are uncrushable, unhackable, auto-verifiable and general. This paper presents Nondeterministic Polynomial-time Problem Challenge (NPPC), an ever-scaling reasoning benchmark for LLMs. Specifically, the NPPC has three main modules: i) npgym, which provides a unified interface of 25 well-known NP-complete problems and can generate any number of instances with any levels of complexities, ii) npsolver: which provides a unified interface to evaluate the problem instances with both online and offline models via APIs and local deployments, respectively, and iii) npeval: which provides the comprehensive and ready-to-use tools to analyze the performances of LLMs over different problems, the number of tokens, the aha moments, the reasoning errors and the solution errors. Extensive experiments over widely-used LLMs demonstrate: i) NPPC can successfully decrease the performances of advanced LLMs' performances to below 10%, demonstrating that NPPC is uncrushable, ii) DeepSeek-R1, Claude-3.7-Sonnet, and o1/o3-mini are the most powerful LLMs, where DeepSeek-R1 outperforms Claude-3.7-Sonnet and o1/o3-mini in most NP-complete problems considered, and iii) the numbers of tokens, aha moments in the advanced LLMs, e.g., Claude-3.7-Sonnet and DeepSeek-R1, are observed first to increase and then decrease when the problem instances become more and more difficult. We believe that NPPC is the first ever-scaling reasoning benchmark, serving as the uncrushable and unhackable testbed for LLMs toward artificial general intelligence (AGI).

Pengdeng Li, Shuxin Li, Chang Yang et al.

Policy-Space Response Oracles (PSRO) as a general algorithmic framework has achieved state-of-the-art performance in learning equilibrium policies of two-player zero-sum games. However, the hand-crafted hyperparameter value selection in most of the existing works requires extensive domain knowledge, forming the main barrier to applying PSRO to different games. In this work, we make the first attempt to investigate the possibility of self-adaptively determining the optimal hyperparameter values in the PSRO framework. Our contributions are three-fold: (1) Using several hyperparameters, we propose a parametric PSRO that unifies the gradient descent ascent (GDA) and different PSRO variants. (2) We propose the self-adaptive PSRO (SPSRO) by casting the hyperparameter value selection of the parametric PSRO as a hyperparameter optimization (HPO) problem where our objective is to learn an HPO policy that can self-adaptively determine the optimal hyperparameter values during the running of the parametric PSRO. (3) To overcome the poor performance of online HPO methods, we propose a novel offline HPO approach to optimize the HPO policy based on the Transformer architecture. Experiments on various two-player zero-sum games demonstrate the superiority of SPSRO over different baselines.

Fuhao Chang, Shuxin Li, Yabei Li et al.

Open-set perception in complex traffic environments poses a critical challenge for autonomous driving systems, particularly in identifying previously unseen object categories, which is vital for ensuring safety. Visual Language Models (VLMs), with their rich world knowledge and strong semantic reasoning capabilities, offer new possibilities for addressing this task. However, existing approaches typically leverage VLMs to extract visual features and couple them with traditional object detectors, resulting in multi-stage error propagation that hinders perception accuracy. To overcome this limitation, we propose VLM-3D, the first end-to-end framework that enables VLMs to perform 3D geometric perception in autonomous driving scenarios. VLM-3D incorporates Low-Rank Adaptation (LoRA) to efficiently adapt VLMs to driving tasks with minimal computational overhead, and introduces a joint semantic-geometric loss design: token-level semantic loss is applied during early training to ensure stable convergence, while 3D IoU loss is introduced in later stages to refine the accuracy of 3D bounding box predictions. Evaluations on the nuScenes dataset demonstrate that the proposed joint semantic-geometric loss in VLM-3D leads to a 12.8% improvement in perception accuracy, fully validating the effectiveness and advancement of our method.

Pengdeng Li, Shuxin Li, Chang Yang et al.

Decision-making problems, categorized as single-agent, e.g., Atari, cooperative multi-agent, e.g., Hanabi, competitive multi-agent, e.g., Hold'em poker, and mixed cooperative and competitive, e.g., football, are ubiquitous in the real world. Various methods are proposed to address the specific decision-making problems. Despite the successes in specific categories, these methods typically evolve independently and cannot generalize to other categories. Therefore, a fundamental question for decision-making is: \emph{Can we develop \textbf{a single algorithm} to tackle \textbf{ALL} categories of decision-making problems?} There are several main challenges to address this question: i) different decision-making categories involve different numbers of agents and different relationships between agents, ii) different categories have different solution concepts and evaluation measures, and iii) there lacks a comprehensive benchmark covering all the categories. This work presents a preliminary attempt to address the question with three main contributions. i) We propose the generalized mirror descent (GMD), a generalization of MD variants, which considers multiple historical policies and works with a broader class of Bregman divergences. ii) We propose the configurable mirror descent (CMD) where a meta-controller is introduced to dynamically adjust the hyper-parameters in GMD conditional on the evaluation measures. iii) We construct the \textsc{GameBench} with 15 academic-friendly games across different decision-making categories. Extensive experiments demonstrate that CMD achieves empirically competitive or better outcomes compared to baselines while providing the capability of exploring diverse dimensions of decision making.

Anzhe Chen, Hongxiang Yu, Shuxin Li et al.

Visual servo based on traditional image matching methods often requires accurate keypoint correspondence for high precision control. However, keypoint detection or matching tends to fail in challenging scenarios with inconsistent illuminations or textureless objects, resulting significant performance degradation. Previous approaches, including our proposed Correspondence encoded Neural image Servo policy (CNS), attempted to alleviate these issues by integrating neural control strategies. While CNS shows certain improvement against error correspondence over conventional image-based controllers, it could not fully resolve the limitations arising from poor keypoint detection and matching. In this paper, we continue to address this problem and propose a new solution: Probabilistic Correspondence Encoded Neural Image Servo (CNSv2). CNSv2 leverages probabilistic feature matching to improve robustness in challenging scenarios. By redesigning the architecture to condition on multimodal feature matching, CNSv2 achieves high precision, improved robustness across diverse scenes and runs in real-time. We validate CNSv2 with simulations and real-world experiments, demonstrating its effectiveness in overcoming the limitations of detector-based methods in visual servo tasks.

Wanqi Xue, Youzhi Zhang, Shuxin Li et al.

Securing networked infrastructures is important in the real world. The problem of deploying security resources to protect against an attacker in networked domains can be modeled as Network Security Games (NSGs). Unfortunately, existing approaches, including the deep learning-based approaches, are inefficient to solve large-scale extensive-form NSGs. In this paper, we propose a novel learning paradigm, NSG-NFSP, to solve large-scale extensive-form NSGs based on Neural Fictitious Self-Play (NFSP). Our main contributions include: i) reforming the best response (BR) policy network in NFSP to be a mapping from action-state pair to action-value, to make the calculation of BR possible in NSGs; ii) converting the average policy network of an NFSP agent into a metric-based classifier, helping the agent to assign distributions only on legal actions rather than all actions; iii) enabling NFSP with high-level actions, which can benefit training efficiency and stability in NSGs; and iv) leveraging information contained in graphs of NSGs by learning efficient graph node embeddings. Our algorithm significantly outperforms state-of-the-art algorithms in both scalability and solution quality.

Shuxin Li, Youzhi Zhang, Xinrun Wang et al.

In many real-world scenarios, a team of agents coordinate with each other to compete against an opponent. The challenge of solving this type of game is that the team's joint action space grows exponentially with the number of agents, which results in the inefficiency of the existing algorithms, e.g., Counterfactual Regret Minimization (CFR). To address this problem, we propose a new framework of CFR: CFR-MIX. Firstly, we propose a new strategy representation that represents a joint action strategy using individual strategies of all agents and a consistency relationship to maintain the cooperation between agents. To compute the equilibrium with individual strategies under the CFR framework, we transform the consistency relationship between strategies to the consistency relationship between the cumulative regret values. Furthermore, we propose a novel decomposition method over cumulative regret values to guarantee the consistency relationship between the cumulative regret values. Finally, we introduce our new algorithm CFR-MIX which employs a mixing layer to estimate cumulative regret values of joint actions as a non-linear combination of cumulative regret values of individual actions. Experimental results show that CFR-MIX outperforms existing algorithms on various games significantly.

Shuxin Li, Zixian Huang, Gong Cheng et al.

A prominent application of knowledge graph (KG) is document enrichment. Existing methods identify mentions of entities in a background KG and enrich documents with entity types and direct relations. We compute an entity relation subgraph (ERG) that can more expressively represent indirect relations among a set of mentioned entities. To find compact, representative, and relevant ERGs for effective enrichment, we propose an efficient best-first search algorithm to solve a new combinatorial optimization problem that achieves a trade-off between representativeness and compactness, and then we exploit ontological knowledge to rank ERGs by entity-based document-KG and intra-KG relevance. Extensive experiments and user studies show the promising performance of our approach.

Shuxin Li, Gong Cheng, Chengkai Li

In many domains we have witnessed the need to search a large entity-relation graph for direct and indirect relationships between a set of entities specified in a query. A search result, called a semantic association (SA), is typically a compact (e.g., diameter-constrained) connected subgraph containing all the query entities. For this problem of SA search, efficient algorithms exist but will return empty results if some query entities are distant in the graph. To reduce the occurrence of failing query and provide alternative results, we study the problem of query relaxation in the context of SA search. Simply relaxing the compactness constraint will sacrifice the compactness of an SA, and more importantly, may lead to performance issues and be impracticable. Instead, we focus on removing the smallest number of entities from the original failing query, to form a maximum successful sub-query which minimizes the loss of result quality caused by relaxation. We prove that verifying the success of a sub-query turns into finding an entity (called a certificate) that satisfies a distance-based condition about the query entities. To efficiently find a certificate of the success of a maximum sub-query, we propose a best-first search algorithm that leverages distance-based estimation to effectively prune the search space. We further improve its performance by adding two fine-grained heuristics: one based on degree and the other based on distance. Extensive experiments over popular RDF datasets demonstrate the efficiency of our algorithm, which is more scalable than baselines.

Xiaxia Wang, Jinchi Chen, Shuxin Li et al.

Reusing existing datasets is of considerable significance to researchers and developers. Dataset search engines help a user find relevant datasets for reuse. They can present a snippet for each retrieved dataset to explain its relevance to the user's data needs. This emerging problem of snippet generation for dataset search has not received much research attention. To provide a basis for future research, we introduce a framework for quantitatively evaluating the quality of a dataset snippet. The proposed metrics assess the extent to which a snippet matches the query intent and covers the main content of the dataset. To establish a baseline, we adapt four state-of-the-art methods from related fields to our problem, and perform an empirical evaluation based on real-world datasets and queries. We also conduct a user study to verify our findings. The results demonstrate the effectiveness of our evaluation framework, and suggest directions for future research.