John C. Platt

Michael P. Brenner, Lizzie Dorfman, John C. Platt

We present a case study for how AI coding systems can be used to generate novel scientific hypotheses. We combine a generic coding agent (Google's AntiGravity) with an LLM-driven tree search algorithm (Empirical Research Assistance / ERA) to autonomously generate high-efficiency three-dimensional photovoltaic (3DPV) structures that overcome losses limiting flat solar panels at mid-latitudes. These structures operate by presenting favorable angles to the sun throughout the day, and for illustrative purposes we focus on optimizing performance for a single solar day. Our workflow begins by using AntiGravity to reproduce calculations \cite{bernardi2012solar} showing that 3DPV can have energy densities much higher than stationary flat PV panels. We use these initial designs as the starting point for large scale tree search, where we seek improved solutions and score them for their diurnal yield. The initial tree search leads to nominally more efficient solutions, yet they are caused by algorithmic reward hacking, arising from non-physical design features such as structurally levitating disconnected tiers and exploitations of the discretizations in the optics solver. To counteract this, we develop a workflow where the coding agent iteratively patches the physics engine with constraints to eliminate reward hacking. With reward-hacking eliminated, ERA discovers a series of designs with various constraints and improved performance, including optimal designs with different fixed collector areas, optimizing zenith tracking and avoiding self shadowing. Combining coding agents with tree search (ERA) provides a powerful platform for scientific discovery, for problems whose solutions can be empirically evaluated with a score function.

Eser Aygün, Anastasiya Belyaeva, Gheorghe Comanici et al.

The cycle of scientific discovery is frequently bottlenecked by the slow, manual creation of software to support computational experiments. To address this, we present an AI system that creates expert-level scientific software whose goal is to maximize a quality metric. The system uses a Large Language Model (LLM) and Tree Search (TS) to systematically improve the quality metric and intelligently navigate the large space of possible solutions. The system achieves expert-level results when it explores and integrates complex research ideas from external sources. The effectiveness of tree search is demonstrated across a wide range of benchmarks. In bioinformatics, it discovered 40 novel methods for single-cell data analysis that outperformed the top human-developed methods on a public leaderboard. In epidemiology, it generated 14 models that outperformed the CDC ensemble and all other individual models for forecasting COVID-19 hospitalizations. Our method also produced state-of-the-art software for geospatial analysis, neural activity prediction in zebrafish, time series forecasting and numerical solution of integrals. By devising and implementing novel solutions to diverse tasks, the system represents a significant step towards accelerating scientific progress.

Talha Ongun, Jack W. Stokes, Jonathan Bar Or et al.

In recent years, enterprises have been targeted by advanced adversaries who leverage creative ways to infiltrate their systems and move laterally to gain access to critical data. One increasingly common evasive method is to hide the malicious activity behind a benign program by using tools that are already installed on user computers. These programs are usually part of the operating system distribution or another user-installed binary, therefore this type of attack is called "Living-Off-The-Land". Detecting these attacks is challenging, as adversaries may not create malicious files on the victim computers and anti-virus scans fail to detect them. We propose the design of an Active Learning framework called LOLAL for detecting Living-Off-the-Land attacks that iteratively selects a set of uncertain and anomalous samples for labeling by a human analyst. LOLAL is specifically designed to work well when a limited number of labeled samples are available for training machine learning models to detect attacks. We investigate methods to represent command-line text using word-embedding techniques, and design ensemble boosting classifiers to distinguish malicious and benign samples based on the embedding representation. We leverage a large, anonymized dataset collected by an endpoint security product and demonstrate that our ensemble classifiers achieve an average F1 score of 0.96 at classifying different attack classes. We show that our active learning method consistently improves the classifier performance, as more training data is labeled, and converges in less than 30 iterations when starting with a small number of labeled instances.

David Rolnick, Priya L. Donti, Lynn H. Kaack et al.

Climate change is one of the greatest challenges facing humanity, and we, as machine learning experts, may wonder how we can help. Here we describe how machine learning can be a powerful tool in reducing greenhouse gas emissions and helping society adapt to a changing climate. From smart grids to disaster management, we identify high impact problems where existing gaps can be filled by machine learning, in collaboration with other fields. Our recommendations encompass exciting research questions as well as promising business opportunities. We call on the machine learning community to join the global effort against climate change.

Dengyong Zhou, Qiang Liu, John C. Platt et al.

There is a rapidly increasing interest in crowdsourcing for data labeling. By crowdsourcing, a large number of labels can be often quickly gathered at low cost. However, the labels provided by the crowdsourcing workers are usually not of high quality. In this paper, we propose a minimax conditional entropy principle to infer ground truth from noisy crowdsourced labels. Under this principle, we derive a unique probabilistic labeling model jointly parameterized by worker ability and item difficulty. We also propose an objective measurement principle, and show that our method is the only method which satisfies this objective measurement principle. We validate our method through a variety of real crowdsourcing datasets with binary, multiclass or ordinal labels.

Hao Fang, Saurabh Gupta, Forrest Iandola et al.

This paper presents a novel approach for automatically generating image descriptions: visual detectors, language models, and multimodal similarity models learnt directly from a dataset of image captions. We use multiple instance learning to train visual detectors for words that commonly occur in captions, including many different parts of speech such as nouns, verbs, and adjectives. The word detector outputs serve as conditional inputs to a maximum-entropy language model. The language model learns from a set of over 400,000 image descriptions to capture the statistics of word usage. We capture global semantics by re-ranking caption candidates using sentence-level features and a deep multimodal similarity model. Our system is state-of-the-art on the official Microsoft COCO benchmark, producing a BLEU-4 score of 29.1%. When human judges compare the system captions to ones written by other people on our held-out test set, the system captions have equal or better quality 34% of the time.