Abdul Rehman

Abdul Rehman, Talha Meraj, Aiman Mahmood Minhas et al.

Earlier diagnosis of Leukemia can save thousands of lives annually. The prognosis of leukemia is challenging without the morphological information of White Blood Cells (WBC) and relies on the accessibility of expensive microscopes and the availability of hematologists to analyze Peripheral Blood Samples (PBS). Deep Learning based methods can be employed to assist hematologists. However, these algorithms require a large amount of labeled data, which is not readily available. To overcome this limitation, we have acquired a realistic, generalized, and large dataset. To collect this comprehensive dataset for real-world applications, two microscopes from two different cost spectrums (high-cost HCM and low-cost LCM) are used for dataset capturing at three magnifications (100x, 40x, 10x) through different sensors (high-end camera for HCM, middle-level camera for LCM and mobile-phone camera for both). The high-sensor camera is 47 times more expensive than the middle-level camera and HCM is 17 times more expensive than LCM. In this collection, using HCM at high resolution (100x), experienced hematologists annotated 10.3k WBC types (14) and artifacts, having 55k morphological labels (Cell Size, Nuclear Chromatin, Nuclear Shape, etc.) from 2.4k images of several PBS leukemia patients. Later on, these annotations are transferred to other 2 magnifications of HCM, and 3 magnifications of LCM, and on each camera captured images. Along with the LeukemiaAttri dataset, we provide baselines over multiple object detectors and Unsupervised Domain Adaptation (UDA) strategies, along with morphological information-based attribute prediction. The dataset will be publicly available after publication to facilitate the research in this direction.

Abdul Rehman, Ilona Heldal, Jerry Chun-Wei Lin

Self Supervised Representation Learning (SSRepL) can capture meaningful and robust representations of the Attention Deficit Hyperactivity Disorder (ADHD) data and have the potential to improve the model's performance on also downstream different types of Neurodevelopmental disorder (NDD) detection. In this paper, a novel SSRepL and Transfer Learning (TL)-based framework that incorporates a Long Short-Term Memory (LSTM) and a Gated Recurrent Units (GRU) model is proposed to detect children with potential symptoms of ADHD. This model uses Electroencephalogram (EEG) signals extracted during visual attention tasks to accurately detect ADHD by preprocessing EEG signal quality through normalization, filtering, and data balancing. For the experimental analysis, we use three different models: 1) SSRepL and TL-based LSTM-GRU model named as SSRepL-ADHD, which integrates LSTM and GRU layers to capture temporal dependencies in the data, 2) lightweight SSRepL-based DNN model (LSSRepL-DNN), and 3) Random Forest (RF). In the study, these models are thoroughly evaluated using well-known performance metrics (i.e., accuracy, precision, recall, and F1-score). The results show that the proposed SSRepL-ADHD model achieves the maximum accuracy of 81.11% while admitting the difficulties associated with dataset imbalance and feature selection.

Abdul Rehman, Iqra Rasool, Ayisha Imran et al.

Digital hematopathology requires cell-level analysis across diverse disease categories, including malignant disorders (e.g., leukemia), infectious conditions (e.g., malaria), and non-malignant red blood cell disorders (e.g., sickle cell disease). Whether single-task, vision-language, WSI-optimized, or single-cell hematology models, these approaches share a key limitation, they cannot provide unified, multi-task, multi-modal reasoning across the complexities of digital hematopathology. To overcome these limitations, we propose Uni-Hema, a multi-task, unified model for digital hematopathology integrating detection, classification, segmentation, morphology prediction, and reasoning across multiple diseases. Uni-Hema leverages 46 publicly available datasets, encompassing over 700K images and 21K question-answer pairs, and is built upon Hema-Former, a multimodal module that bridges visual and textual representations at the hierarchy level for the different tasks (detection, classification, segmentation, morphology, mask language modeling and visual question answer) at different granularity. Extensive experiments demonstrate that Uni-Hema achieves comparable or superior performance to train on a single-task and single dataset models, across diverse hematological tasks, while providing interpretable, morphologically relevant insights at the single-cell level. Our framework establishes a new standard for multi-task and multi-modal digital hematopathology. The code will be made publicly available.

Abdul Rehman, Are Dæhlen, Ilona Heldal et al.

Eye-tracking technology can aid in understanding neurodevelopmental disorders and tracing a person's identity. However, this technology poses a significant risk to privacy, as it captures sensitive information about individuals and increases the likelihood that data can be traced back to them. This paper proposes a human-centered framework designed to prevent identity backtracking while preserving the pedagogical benefits of AI-powered eye tracking in interactive learning environments. We explore how real-time data anonymization, ethical design principles, and regulatory compliance (such as GDPR) can be integrated to build trust and transparency. We first demonstrate the potential for backtracking student IDs and diagnoses in various scenarios using serious game-based eye-tracking data. We then provide a two-stage privacy-preserving framework that prevents participants from being tracked while still enabling diagnostic classification. The first phase covers four scenarios: I) Predicting disorder diagnoses based on different game levels. II) Predicting student IDs based on different game levels. III) Predicting student IDs based on randomized data. IV) Utilizing K-Means for out-of-sample data. In the second phase, we present a two-stage framework that preserves privacy. We also employ Federated Learning (FL) across multiple clients, incorporating a secure identity management system with dummy IDs and administrator-only access controls. In the first phase, the proposed framework achieved 99.3% accuracy for scenario 1, 63% accuracy for scenario 2, and 99.7% accuracy for scenario 3, successfully identifying and assigning a new student ID in scenario 4. In phase 2, we effectively prevented backtracking and established a secure identity management system with dummy IDs and administrator-only access controls, achieving an overall accuracy of 99.40%.

Abdul Rehman, Ilona Heldal, Jerry Chun-Wei Lin

Recent advancements in EEG-based emotion recognition have shown promising outcomes using both deep learning and classical machine learning approaches; however, most existing studies focus narrowly on binary valence prediction or subject-specific classification, which limits generalizability and deployment in real-world affective computing systems. To address this gap, this paper presents a unified, multigranularity EEG emotion classification framework built on the GAMEEMO dataset, which consists of 14-channel EEG recordings and continuous self-reported emotion ratings (boring, horrible, calm, and funny) from 28 subjects across four emotion-inducing gameplay scenarios. Our pipeline employs a structured preprocessing strategy that comprises temporal window segmentation, hybrid statistical and frequency-domain feature extraction, and z-score normalization to convert raw EEG signals into robust, discriminative input vectors. Emotion labels are derived and encoded across three complementary axes: (i) binary valence classification based on the averaged polarity of positive and negative emotion ratings, and (ii) Multi-class emotion classification, where the presence of the most affective state is predicted. (iii) Fine-grained multi-label representation via binning each emotion into 10 ordinal classes. We evaluate a broad spectrum of models, including Random Forest, XGBoost, and SVM, alongside deep neural architectures such as LSTM, LSTM-GRU, and CNN-LSTM. Among these, the LSTM-GRU model consistently outperforms the others, achieving an F1-score of 0.932 in the binary valence task and 94.5% and 90.6% in both multi-class and Multi-Label emotion classification.

Mustansar Fiaz, Kamran Ali, Abdul Rehman et al.

Medical image segmentation being a substantial component of image processing plays a significant role to analyze gross anatomy, to locate an infirmity and to plan the surgical procedures. Segmentation of brain Magnetic Resonance Imaging (MRI) is of considerable importance for the accurate diagnosis. However, precise and accurate segmentation of brain MRI is a challenging task. Here, we present an efficient framework for segmentation of brain MR images. For this purpose, Gabor transform method is used to compute features of brain MRI. Then, these features are classified by using four different classifiers i.e., Incremental Supervised Neural Network (ISNN), K-Nearest Neighbor (KNN), Probabilistic Neural Network (PNN), and Support Vector Machine (SVM). Performance of these classifiers is investigated over different images of brain MRI and the variation in the performance of these classifiers is observed for different brain tissues. Thus, we proposed a rule-based hybrid approach to segment brain MRI. Experimental results show that the performance of these classifiers varies over each tissue MRI and the proposed rule-based hybrid approach exhibits better segmentation of brain MRI tissues.