A S M Ahsanul Sarkar Akib

Susmita Kar, A S M Ahsanul Sarkar Akib, Abdul Hasib et al.

Diabetic retinopathy (DR), affecting millions globally with projections indicating a significant rise, poses a severe blindness risk and strains healthcare systems. Diagnostic complexity arises from visual symptom overlap with conditions like age-related macular degeneration and hypertensive retinopathy, exacerbated by high misdiagnosis rates in underserved regions. This study introduces TIMM-ProRS, a novel deep learning framework integrating Vision Transformer (ViT), Convolutional Neural Network (CNN), and Graph Neural Network (GNN) with multi-modal fusion. TIMM-ProRS uniquely leverages both retinal images and temporal biomarkers (HbA1c, retinal thickness) to capture multi-modal and temporal dynamics. Evaluated comprehensively across diverse datasets including APTOS 2019 (trained), Messidor-2, RFMiD, EyePACS, and Messidor-1 (validated), the model achieves 97.8\% accuracy and an F1-score of 0.96, demonstrating state-of-the-art performance and outperforming existing methods like RSG-Net and DeepDR. This approach enables early, precise, and interpretable diagnosis, supporting scalable telemedical management and enhancing global eye health sustainability.

A S M Ahsanul Sarkar Akib, Raduana Khawla, Abdul Hasib

Stroke is a major cause of death and permanent impairment, making it a major worldwide health concern. For prompt intervention and successful preventative tactics, early risk assessment is essential. To address this challenge, we used ensemble modeling and explainable AI (XAI) techniques to create an interpretable machine learning framework for stroke risk prediction. A thorough evaluation of 10 different machine learning models using 5-fold cross-validation across several datasets was part of our all-inclusive strategy, which also included feature engineering and data pretreatment (using Random Over-Sampling (ROS) to solve class imbalance). Our optimized ensemble model (Random Forest + ExtraTrees + XGBoost) performed exceptionally well, obtaining a strong 99.09% accuracy on the Stroke Prediction Dataset (SPD). We improved the model's transparency and clinical applicability by identifying three important clinical variables using LIME-based interpretability analysis: age, hypertension, and glucose levels. Through early prediction, this study highlights how combining ensemble learning with explainable AI (XAI) can deliver highly accurate and interpretable stroke risk assessment. By enabling data-driven prevention and personalized clinical decisions, our framework has the potential to transform stroke prediction and cardiovascular risk management.

Md. Maksudul Haque, Rahnuma Akter, A S M Ahsanul Sarkar Akib et al.

Skin cancer is also one of the most common and dangerous types of cancer in the world that requires timely and precise diagnosis. In this paper, a deep-learning architecture of the multi-class skin lesion classification on the HAM10000 dataset will be described. The system suggested combines high-quality data balancing methods, large-scale data augmentation, hybridized EfficientNetV2-L framework with channel attention, and a three-stage progressive learning approach. Moreover, we also use explainable AI (XAI) techniques such as Grad-CAM and saliency maps to come up with intelligible visual representations of model predictions. Our strategy is with a total accuracy of 91.15 per cent, macro F1 of 85.45\% and micro-average AUC of 99.33\%. The model has shown high performance in all the seven lesion classes with specific high performance of melanoma and melanocytic nevi. In addition to enhancing diagnostic transparency, XAI also helps to find out the visual characteristics that cause the classifications, which enhances clinical trustworthiness.