Amir Aly

Suryansh Vidya, Kush Gupta, Amir Aly et al.

Early diagnosis and intervention for Autism Spectrum Disorder (ASD) has been shown to significantly improve the quality of life of autistic individuals. However, diagnostics methods for ASD rely on assessments based on clinical presentation that are prone to bias and can be challenging to arrive at an early diagnosis. There is a need for objective biomarkers of ASD which can help improve diagnostic accuracy. Deep learning (DL) has achieved outstanding performance in diagnosing diseases and conditions from medical imaging data. Extensive research has been conducted on creating models that classify ASD using resting-state functional Magnetic Resonance Imaging (fMRI) data. However, existing models lack interpretability. This research aims to improve the accuracy and interpretability of ASD diagnosis by creating a DL model that can not only accurately classify ASD but also provide explainable insights into its working. The dataset used is a preprocessed version of the Autism Brain Imaging Data Exchange (ABIDE) with 884 samples. Our findings show a model that can accurately classify ASD and highlight critical brain regions differing between ASD and typical controls, with potential implications for early diagnosis and understanding of the neural basis of ASD. These findings are validated by studies in the literature that use different datasets and modalities, confirming that the model actually learned characteristics of ASD and not just the dataset. This study advances the field of explainable AI in medical imaging by providing a robust and interpretable model, thereby contributing to a future with objective and reliable ASD diagnostics.

Kush Gupta, Amir Aly, Emmanuel Ifeachor et al.

Autism spectrum disorder (ASD) is a neurodevelopmental condition characterized by atypical brain maturation. However, the adaptation of transfer learning paradigms in machine learning for ASD research remains notably limited. In this study, we propose a computer-aided diagnostic framework with two modules. This chapter presents a two-module framework combining deep learning and explainable AI for ASD diagnosis. The first module leverages a deep learning model fine-tuned through cross-domain transfer learning for ASD classification. The second module focuses on interpreting the model decisions and identifying critical brain regions. To achieve this, we employed three explainable AI (XAI) techniques: saliency mapping, Gradient-weighted Class Activation Mapping, and SHapley Additive exPlanations (SHAP) analysis. This framework demonstrates that cross-domain transfer learning can effectively address data scarcity in ASD research. In addition, by applying three established explainability techniques, the approach reveals how the model makes diagnostic decisions and identifies brain regions most associated with ASD. These findings were compared against established neurobiological evidence, highlighting strong alignment and reinforcing the clinical relevance of the proposed approach.

Andreea Peca, Adriana Tapus, Amir Aly et al.

This paper presents an exploratory study designed for children with Autism Spectrum Disorders (ASD) that investigates children's awareness of being imitated by a robot in a play/game scenario. The Nao robot imitates all the arm movement behaviors of the child in real-time in dyadic and triadic interactions. Different behavioral criteria (i.e., eye gaze, gaze shifting, initiation and imitation of arm movements, smile/laughter) were analyzed based on the video data of the interaction. The results confirm only parts of the research hypothesis. However, these results are promising for the future directions of this work.

Adriana Tapus, Andreea Peca, Amir Aly et al.

Imitation plays an important role in development, being one of the precursors of social cognition. Even though some children with autism imitate spontaneously and other children with autism can learn to imitate, the dynamics of imitation is affected in the large majority of cases. Existing studies from the literature suggest that robots can be used to teach children with autism basic interaction skills like imitation. Based on these findings, in this study, we investigate if children with autism show more social engagement when interacting with an imitative robot (Fig 1) compared to a human partner in a motor imitation task.

Amir Aly

This study proposes different approaches for static and dynamic gesture analysis and imitation with the social robot Nao

Amir Aly, Tadahiro Taniguchi

Robots are widely collaborating with human users in diferent tasks that require high-level cognitive functions to make them able to discover the surrounding environment. A difcult challenge that we briefy highlight in this short paper is inferring the latent grammatical structure of language, which includes grounding parts of speech (e.g., verbs, nouns, adjectives, and prepositions) through visual perception, and induction of Combinatory Categorial Grammar (CCG) for phrases. This paves the way towards grounding phrases so as to make a robot able to understand human instructions appropriately during interaction.