Emmanuel Ifeachor

Suryansh Vidya, Kush Gupta, Amir Aly et al.

Early diagnosis and intervention for Autism Spectrum Disorder (ASD) has been shown to significantly improve the quality of life of autistic individuals. However, diagnostics methods for ASD rely on assessments based on clinical presentation that are prone to bias and can be challenging to arrive at an early diagnosis. There is a need for objective biomarkers of ASD which can help improve diagnostic accuracy. Deep learning (DL) has achieved outstanding performance in diagnosing diseases and conditions from medical imaging data. Extensive research has been conducted on creating models that classify ASD using resting-state functional Magnetic Resonance Imaging (fMRI) data. However, existing models lack interpretability. This research aims to improve the accuracy and interpretability of ASD diagnosis by creating a DL model that can not only accurately classify ASD but also provide explainable insights into its working. The dataset used is a preprocessed version of the Autism Brain Imaging Data Exchange (ABIDE) with 884 samples. Our findings show a model that can accurately classify ASD and highlight critical brain regions differing between ASD and typical controls, with potential implications for early diagnosis and understanding of the neural basis of ASD. These findings are validated by studies in the literature that use different datasets and modalities, confirming that the model actually learned characteristics of ASD and not just the dataset. This study advances the field of explainable AI in medical imaging by providing a robust and interpretable model, thereby contributing to a future with objective and reliable ASD diagnostics.

Kush Gupta, Amir Aly, Emmanuel Ifeachor et al.

Autism spectrum disorder (ASD) is a neurodevelopmental condition characterized by atypical brain maturation. However, the adaptation of transfer learning paradigms in machine learning for ASD research remains notably limited. In this study, we propose a computer-aided diagnostic framework with two modules. This chapter presents a two-module framework combining deep learning and explainable AI for ASD diagnosis. The first module leverages a deep learning model fine-tuned through cross-domain transfer learning for ASD classification. The second module focuses on interpreting the model decisions and identifying critical brain regions. To achieve this, we employed three explainable AI (XAI) techniques: saliency mapping, Gradient-weighted Class Activation Mapping, and SHapley Additive exPlanations (SHAP) analysis. This framework demonstrates that cross-domain transfer learning can effectively address data scarcity in ASD research. In addition, by applying three established explainability techniques, the approach reveals how the model makes diagnostic decisions and identifies brain regions most associated with ASD. These findings were compared against established neurobiological evidence, highlighting strong alignment and reinforcing the clinical relevance of the proposed approach.

Alcardo Alex Barakabitze, Lingfen Sun, Is-Haka Mkwawa et al.

This paper proposes a novel QoE-aware SDN enabled NFV architecture for controlling and managing Future Multimedia Applications on 5G systems. The aim is to improve the QoE of the delivered multimedia services through the fulfilment of personalized QoE application requirements. This novel approach provides some new features, functionalities, concepts and opportunities for overcoming the key QoE provisioning limitations in current 4G systems such as increased network management complexity and inability to adapt dynamically to changing application, network transmission or traffic or end-users demand.