Paulo Borba

Rodrigo Mota, Kelvin Cunha, Emanoel dos Santos et al.

Deep learning models for dermatological image analysis remain sensitive to acquisition variability and domain-specific visual characteristics, leading to performance degradation when deployed in clinical settings. We investigate how visual artifacts and domain shifts affect deep learning-based skin lesion classification. We propose an adaptation strategy, grounded in the idea of visual meta-domains, that transfers visual representations from larger dermoscopic datasets into clinical image domains, thereby improving generalization robustness. Experiments across multiple dermatology datasets show consistent gains in classification performance and reduced gaps between dermoscopic and clinical images. These results emphasize the importance of domain-aware training for deployable systems.

Francisco Filho, Kelvin Cunha, Fábio Papais et al.

Skin lesion classification datasets often suffer from severe class imbalance, with malignant cases significantly underrepresented, leading to biased decision boundaries during deep learning training. We address this challenge using class-conditioned diffusion models to generate synthetic dermatological images, followed by self-supervised MAE pretraining to enable huge ViT models to learn robust, domain-relevant features. To support deployment in practical clinical settings, where lightweight models are required, we apply knowledge distillation to transfer these representations to a smaller ViT student suitable for mobile devices. Our results show that MAE pretraining on synthetic data, combined with distillation, improves classification performance while enabling efficient on-device inference for practical clinical use.

Thales Bezerra, Emanoel Thyago, Kelvin Cunha et al.

AI-based dermatology adoption remains limited by biased datasets, variable image quality, and limited validation. We introduce DermAI, a lightweight, smartphone-based application that enables real-time capture, annotation, and classification of skin lesions during routine consultations. Unlike prior dermoscopy-focused tools, DermAI performs on-device quality checks, and local model adaptation. The DermAI clinical dataset, encompasses a wide range of skin tones, ethinicity and source devices. In preliminary experiments, models trained on public datasets failed to generalize to our samples, while fine-tuning with local data improved performance. These results highlight the importance of standardized, diverse data collection aligned with healthcare needs and oriented to machine learning development.

Francisco Filho, Emanoel Santos, Rodrigo Mota et al.

AI algorithms have become valuable in aiding professionals in healthcare. The increasing confidence obtained by these models is helpful in critical decision demands. In clinical dermatology, classification models can detect malignant lesions on patients' skin using only RGB images as input. However, most learning-based methods employ data acquired from dermoscopic datasets on training, which are large and validated by a gold standard. Clinical models aim to deal with classification on users' smartphone cameras that do not contain the corresponding resolution provided by dermoscopy. Also, clinical applications bring new challenges. It can contain captures from uncontrolled environments, skin tone variations, viewpoint changes, noises in data and labels, and unbalanced classes. A possible alternative would be to use transfer learning to deal with the clinical images. However, as the number of samples is low, it can cause degradations on the model's performance; the source distribution used in training differs from the test set. This work aims to evaluate the gap between dermoscopic and clinical samples and understand how the dataset variations impact training. It assesses the main differences between distributions that disturb the model's prediction. Finally, from experiments on different architectures, we argue how to combine the data from divergent distributions, decreasing the impact on the model's final accuracy.

Silvio Meira, Vanilson Burégio, Paulo Borba et al.

Since the early days of computers and programs, the process and outcomes of software development has been a minefield plagued with problems and failures, as much as the complexity and complication of software and its development has increased by a thousandfold in half a century. Over the years, a number of theories, laws, best practices, manifestos and methodologies have emerged, with varied degrees of (un)success. Our experience as software engineers of complex and large-scale systems shows that those guidelines are bound to previously defined and often narrow scopes. Enough is enough. Nowadays, nearly every company is in the software and services business and everything is - or is managed by - software. It is about time, then, that the laws that govern our universe ought to be redefined. In this context, we discuss and present a set of universal laws that leads us to propose the first commandment of software engineering for all varieties of information systems.