Jiamin Wu

June M. Liu, Donghao Li, He Cao et al.

This paper presents ChatCounselor, a large language model (LLM) solution designed to provide mental health support. Unlike generic chatbots, ChatCounselor is distinguished by its foundation in real conversations between consulting clients and professional psychologists, enabling it to possess specialized knowledge and counseling skills in the field of psychology. The training dataset, Psych8k, was constructed from 260 in-depth interviews, each spanning an hour. To assess the quality of counseling responses, the counseling Bench was devised. Leveraging GPT-4 and meticulously crafted prompts based on seven metrics of psychological counseling assessment, the model underwent evaluation using a set of real-world counseling questions. Impressively, ChatCounselor surpasses existing open-source models in the counseling Bench and approaches the performance level of ChatGPT, showcasing the remarkable enhancement in model capability attained through high-quality domain-specific data.

Chenfan Xu, Zhentao Liu, Yuan Liu et al.

Orthodontic treatment usually requires regular face-to-face examinations to monitor dental conditions of the patients. When in-person diagnosis is not feasible, an alternative is to utilize five intra-oral photographs for remote dental monitoring. However, it lacks of 3D information, and how to reconstruct 3D dental models from such sparse view photographs is a challenging problem. In this study, we propose a 3D teeth reconstruction framework, named TeethDreamer, aiming to restore the shape and position of the upper and lower teeth. Given five intra-oral photographs, our approach first leverages a large diffusion model's prior knowledge to generate novel multi-view images with known poses to address sparse inputs and then reconstructs high-quality 3D teeth models by neural surface reconstruction. To ensure the 3D consistency across generated views, we integrate a 3D-aware feature attention mechanism in the reverse diffusion process. Moreover, a geometry-aware normal loss is incorporated into the teeth reconstruction process to enhance geometry accuracy. Extensive experiments demonstrate the superiority of our method over current state-of-the-arts, giving the potential to monitor orthodontic treatment remotely. Our code is available at https://github.com/ShanghaiTech-IMPACT/TeethDreamer

Jiayin Zhao, Zhifeng Zhao, Jiamin Wu et al.

Light field microscopy (LFM) has been widely utilized in various fields for its capability to efficiently capture high-resolution 3D scenes. Despite the rapid advancements in neural representations, there are few methods specifically tailored for microscopic scenes. Existing approaches often do not adequately address issues such as the loss of high-frequency information due to defocus and sample aberration, resulting in suboptimal performance. In addition, existing methods, including RLD, INR, and supervised U-Net, face challenges such as sensitivity to initial estimates, reliance on extensive labeled data, and low computational efficiency, all of which significantly diminish the practicality in complex biological scenarios. This paper introduces PNR (Physics-informed Neural Representation), a method for high-resolution LFM reconstruction that significantly enhances performance. Our method incorporates an unsupervised and explicit feature representation approach, resulting in a 6.1 dB improvement in PSNR than RLD. Additionally, our method employs a frequency-based training loss, enabling better recovery of high-frequency details, which leads to a reduction in LPIPS by at least half compared to SOTA methods (1.762 V.S. 3.646 of DINER). Moreover, PNR integrates a physics-informed aberration correction strategy that optimizes Zernike polynomial parameters during optimization, thereby reducing the information loss caused by aberrations and improving spatial resolution. These advancements make PNR a promising solution for long-term high-resolution biological imaging applications. Our code and dataset will be made publicly available.

Jiamin Wu, Kenkun Liu, Han Gao et al.

Recently, Gaussian splatting has demonstrated significant success in novel view synthesis. Current methods often regress Gaussians with pixel or point cloud correspondence, linking each Gaussian with a pixel or a 3D point. This leads to the redundancy of Gaussians being used to overfit the correspondence rather than the objects represented by the 3D Gaussians themselves, consequently wasting resources and lacking accurate geometries or textures. In this paper, we introduce LeanGaussian, a novel approach that treats each query in deformable Transformer as one 3D Gaussian ellipsoid, breaking the pixel or point cloud correspondence constraints. We leverage deformable decoder to iteratively refine the Gaussians layer-by-layer with the image features as keys and values. Notably, the center of each 3D Gaussian is defined as 3D reference points, which are then projected onto the image for deformable attention in 2D space. On both the ShapeNet SRN dataset (category level) and the Google Scanned Objects dataset (open-category level, trained with the Objaverse dataset), our approach, outperforms prior methods by approximately 6.1%, achieving a PSNR of 25.44 and 22.36, respectively. Additionally, our method achieves a 3D reconstruction speed of 7.2 FPS and rendering speed 500 FPS. Codes are available at https://github.com/jwubz123/LeanGaussian.

Jiamin Wu, Kenkun Liu, Yukai Shi et al.

In this work, we introduce UniGS, a novel 3D Gaussian reconstruction and novel view synthesis model that predicts a high-fidelity representation of 3D Gaussians from arbitrary number of posed sparse-view images. Previous methods often regress 3D Gaussians locally on a per-pixel basis for each view and then transfer them to world space and merge them through point concatenation. In contrast, Our approach involves modeling unitary 3D Gaussians in world space and updating them layer by layer. To leverage information from multi-view inputs for updating the unitary 3D Gaussians, we develop a DETR (DEtection TRansformer)-like framework, which treats 3D Gaussians as queries and updates their parameters by performing multi-view cross-attention (MVDFA) across multiple input images, which are treated as keys and values. This approach effectively avoids `ghosting' issue and allocates more 3D Gaussians to complex regions. Moreover, since the number of 3D Gaussians used as decoder queries is independent of the number of input views, our method allows arbitrary number of multi-view images as input without causing memory explosion or requiring retraining. Extensive experiments validate the advantages of our approach, showcasing superior performance over existing methods quantitatively (improving PSNR by 4.2 dB when trained on Objaverse and tested on the GSO benchmark) and qualitatively. The code will be released at https://github.com/jwubz123/UNIG.

Zhanqiang Guo, Jiamin Wu, Yonghao Song et al.

Human's perception of the visual world is shaped by the stereo processing of 3D information. Understanding how the brain perceives and processes 3D visual stimuli in the real world has been a longstanding endeavor in neuroscience. Towards this goal, we introduce a new neuroscience task: decoding 3D visual perception from EEG signals, a neuroimaging technique that enables real-time monitoring of neural dynamics enriched with complex visual cues. To provide the essential benchmark, we first present EEG-3D, a pioneering dataset featuring multimodal analysis data and extensive EEG recordings from 12 subjects viewing 72 categories of 3D objects rendered in both videos and images. Furthermore, we propose Neuro-3D, a 3D visual decoding framework based on EEG signals. This framework adaptively integrates EEG features derived from static and dynamic stimuli to learn complementary and robust neural representations, which are subsequently utilized to recover both the shape and color of 3D objects through the proposed diffusion-based colored point cloud decoder. To the best of our knowledge, we are the first to explore EEG-based 3D visual decoding. Experiments indicate that Neuro-3D not only reconstructs colored 3D objects with high fidelity, but also learns effective neural representations that enable insightful brain region analysis. The dataset and associated code will be made publicly available.

Yuqin Dai, Zhouheng Yao, Chunfeng Song et al.

Brain decoding aims to reconstruct visual perception of human subject from fMRI signals, which is crucial for understanding brain's perception mechanisms. Existing methods are confined to the single-subject paradigm due to substantial brain variability, which leads to weak generalization across individuals and incurs high training costs, exacerbated by limited availability of fMRI data. To address these challenges, we propose MindAligner, an explicit functional alignment framework for cross-subject brain decoding from limited fMRI data. The proposed MindAligner enjoys several merits. First, we learn a Brain Transfer Matrix (BTM) that projects the brain signals of an arbitrary new subject to one of the known subjects, enabling seamless use of pre-trained decoding models. Second, to facilitate reliable BTM learning, a Brain Functional Alignment module is proposed to perform soft cross-subject brain alignment under different visual stimuli with a multi-level brain alignment loss, uncovering fine-grained functional correspondences with high interpretability. Experiments indicate that MindAligner not only outperforms existing methods in visual decoding under data-limited conditions, but also provides valuable neuroscience insights in cross-subject functional analysis. The code will be made publicly available.

Ming Hu, Chenglong Ma, Wei Li et al. · pku

Scientific Large Language Models (Sci-LLMs) are transforming how knowledge is represented, integrated, and applied in scientific research, yet their progress is shaped by the complex nature of scientific data. This survey presents a comprehensive, data-centric synthesis that reframes the development of Sci-LLMs as a co-evolution between models and their underlying data substrate. We formulate a unified taxonomy of scientific data and a hierarchical model of scientific knowledge, emphasizing the multimodal, cross-scale, and domain-specific challenges that differentiate scientific corpora from general natural language processing datasets. We systematically review recent Sci-LLMs, from general-purpose foundations to specialized models across diverse scientific disciplines, alongside an extensive analysis of over 270 pre-/post-training datasets, showing why Sci-LLMs pose distinct demands -- heterogeneous, multi-scale, uncertainty-laden corpora that require representations preserving domain invariance and enabling cross-modal reasoning. On evaluation, we examine over 190 benchmark datasets and trace a shift from static exams toward process- and discovery-oriented assessments with advanced evaluation protocols. These data-centric analyses highlight persistent issues in scientific data development and discuss emerging solutions involving semi-automated annotation pipelines and expert validation. Finally, we outline a paradigm shift toward closed-loop systems where autonomous agents based on Sci-LLMs actively experiment, validate, and contribute to a living, evolving knowledge base. Collectively, this work provides a roadmap for building trustworthy, continually evolving artificial intelligence (AI) systems that function as a true partner in accelerating scientific discovery.

Yuchen Zhou, Jiamin Wu, Zichen Ren et al.

Understanding and decoding brain activity from electroencephalography (EEG) signals is a fundamental challenge in neuroscience and AI, with applications in cognition, emotion recognition, diagnosis, and brain-computer interfaces. While recent EEG foundation models advance generalized decoding via unified architectures and large-scale pretraining, they adopt a scale-agnostic dense modeling paradigm inherited from NLP and vision. This design neglects a core property of neural activity: cross-scale spatiotemporal structure. EEG task patterns span a wide range of temporal and spatial scales, from short bursts to slow rhythms, and from localized cortical responses to distributed interactions. Ignoring this diversity leads to suboptimal representations and weak generalization. We propose CSBrain, a Cross-scale Spatiotemporal Brain foundation model for generalized EEG decoding. CSBrain introduces: (i) Cross-scale Spatiotemporal Tokenization (CST), which aggregates multi-scale features from localized temporal windows and anatomical brain regions into compact scale-aware tokens; and (ii) Structured Sparse Attention (SSA), which captures cross-window and cross-region dependencies, enhancing scale diversity while removing spurious correlations. CST and SSA are alternately stacked to progressively integrate multi-scale dependencies. Experiments on 11 EEG tasks across 16 datasets show that CSBrain consistently outperforms task-specific and foundation model baselines. These results establish cross-scale modeling as a key inductive bias and position CSBrain as a robust backbone for future brain-AI research.

Jiamin Wu, Hongyang Li, Xiaoke Jiang et al.

In this work, we introduce Coca-Splat, a novel approach to addressing the challenges of sparse view pose-free scene reconstruction and novel view synthesis (NVS) by jointly optimizing camera parameters with 3D Gaussians. Inspired by deformable DEtection TRansformer, we design separate queries for 3D Gaussians and camera parameters and update them layer by layer through deformable Transformer layers, enabling joint optimization in a single network. This design demonstrates better performance because to accurately render views that closely approximate ground-truth images relies on precise estimation of both 3D Gaussians and camera parameters. In such a design, the centers of 3D Gaussians are projected onto each view by camera parameters to get projected points, which are regarded as 2D reference points in deformable cross-attention. With camera-aware multi-view deformable cross-attention (CaMDFA), 3D Gaussians and camera parameters are intrinsically connected by sharing the 2D reference points. Additionally, 2D reference point determined rays (RayRef) defined from camera centers to the reference points assist in modeling relationship between 3D Gaussians and camera parameters through RQ-decomposition on an overdetermined system of equations derived from the rays, enhancing the relationship between 3D Gaussians and camera parameters. Extensive evaluation shows that our approach outperforms previous methods, both pose-required and pose-free, on RealEstate10K and ACID within the same pose-free setting.