Xibin Jia

Chao Fan, Hongyuan Yu, Yan Huang et al.

Despite the progress made in Mamba-based medical image segmentation models, existing methods utilizing unidirectional or multi-directional feature scanning mechanisms struggle to effectively capture dependencies between neighboring positions, limiting the discriminant representation learning of local features. These local features are crucial for medical image segmentation as they provide critical structural information about lesions and organs. To address this limitation, we propose SliceMamba, a simple and effective locally sensitive Mamba-based medical image segmentation model. SliceMamba includes an efficient Bidirectional Slice Scan module (BSS), which performs bidirectional feature slicing and employs varied scanning mechanisms for sliced features with distinct shapes. This design ensures that spatially adjacent features remain close in the scanning sequence, thereby improving segmentation performance. Additionally, to fit the varying sizes and shapes of lesions and organs, we further introduce an Adaptive Slice Search method to automatically determine the optimal feature slice method based on the characteristics of the target data. Extensive experiments on two skin lesion datasets (ISIC2017 and ISIC2018), two polyp segmentation (Kvasir and ClinicDB) datasets, and one multi-organ segmentation dataset (Synapse) validate the effectiveness of our method.

Chao Fan, Xibin Jia, Anqi Xiao et al.

Few-Shot Medical Image Segmentation (FSMIS) aims to segment novel classes of medical objects using only a few labeled images. Prototype-based methods have made significant progress in addressing FSMIS. However, they typically generate a single global prototype for the support image to match with the query image, overlooking intra-class variations. To address this issue, we propose a Self-guided Prototype Enhancement Network (SPENet). Specifically, we introduce a Multi-level Prototype Generation (MPG) module, which enables multi-granularity measurement between the support and query images by simultaneously generating a global prototype and an adaptive number of local prototypes. Additionally, we observe that not all local prototypes in the support image are beneficial for matching, especially when there are substantial discrepancies between the support and query images. To alleviate this issue, we propose a Query-guided Local Prototype Enhancement (QLPE) module, which adaptively refines support prototypes by incorporating guidance from the query image, thus mitigating the negative effects of such discrepancies. Extensive experiments on three public medical datasets demonstrate that SPENet outperforms existing state-of-the-art methods, achieving superior performance.