Anni Zou

Xiangru Tang, Anni Zou, Zhuosheng Zhang et al.

Large language models (LLMs), despite their remarkable progress across various general domains, encounter significant barriers in medicine and healthcare. This field faces unique challenges such as domain-specific terminologies and reasoning over specialized knowledge. To address these issues, we propose MedAgents, a novel multi-disciplinary collaboration framework for the medical domain. MedAgents leverages LLM-based agents in a role-playing setting that participate in a collaborative multi-round discussion, thereby enhancing LLM proficiency and reasoning capabilities. This training-free framework encompasses five critical steps: gathering domain experts, proposing individual analyses, summarising these analyses into a report, iterating over discussions until a consensus is reached, and ultimately making a decision. Our work focuses on the zero-shot setting, which is applicable in real-world scenarios. Experimental results on nine datasets (MedQA, MedMCQA, PubMedQA, and six subtasks from MMLU) establish that our proposed MedAgents framework excels at mining and harnessing the medical expertise within LLMs, as well as extending its reasoning abilities. Our code can be found at https://github.com/gersteinlab/MedAgents.

Anni Zou, Wenhao Yu, Hongming Zhang et al.

Recently, there has been a growing interest among large language model (LLM) developers in LLM-based document reading systems, which enable users to upload their own documents and pose questions related to the document contents, going beyond simple reading comprehension tasks. Consequently, these systems have been carefully designed to tackle challenges such as file parsing, metadata extraction, multi-modal information understanding and long-context reading. However, no current benchmark exists to evaluate their performance in such scenarios, where a raw file and questions are provided as input, and a corresponding response is expected as output. In this paper, we introduce DocBench, a new benchmark designed to evaluate LLM-based document reading systems. Our benchmark involves a meticulously crafted process, including the recruitment of human annotators and the generation of synthetic questions. It includes 229 real documents and 1,102 questions, spanning across five different domains and four major types of questions. We evaluate both proprietary LLM-based systems accessible via web interfaces or APIs, and a parse-then-read pipeline employing open-source LLMs. Our evaluations reveal noticeable gaps between existing LLM-based document reading systems and human performance, underscoring the challenges of developing proficient systems. To summarize, DocBench aims to establish a standardized benchmark for evaluating LLM-based document reading systems under diverse real-world scenarios, thereby guiding future advancements in this research area.

Anni Zou, Zhuosheng Zhang, Hai Zhao et al.

Large language models (LLMs) have unveiled remarkable reasoning capabilities by exploiting chain-of-thought (CoT) prompting, which generates intermediate reasoning chains to serve as the rationale for deriving the answer. However, current CoT methods either simply employ general prompts such as Let's think step by step, or heavily rely on pre-defined task-specific demonstrations to attain preferable performances, thereby engendering an inescapable gap between performance and generalization. To bridge this gap, we propose GeM-CoT, a Generalizable CoT prompting mechanism in Mixed-task scenarios where the type of input questions is unknown. GeM-CoT first categorizes the question type and subsequently samples or constructs demonstrations from the corresponding data pool in an automatic pattern. With this technical design, GeM-CoT simultaneously enjoys superior generalization capabilities and remarkable performances on 10 public reasoning tasks and 23 BBH tasks.

Shinji Mai, Yunpeng Zhai, Ziqian Chen et al.

Large language model based agents are increasingly deployed in complex, tool augmented environments. While reinforcement learning provides a principled mechanism for such agents to improve through interaction, its effectiveness critically depends on the availability of structured training tasks. In many realistic settings, however, no such tasks exist a challenge we term task scarcity, which has become a key bottleneck for scaling agentic RL. Existing approaches typically assume predefined task collections, an assumption that fails in novel environments where tool semantics and affordances are initially unknown. To address this limitation, we formalize the problem of Task Generation for Agentic RL, where an agent must learn within a given environment that lacks predefined tasks. We propose CuES, a Curiosity driven and Environment grounded Synthesis framework that autonomously generates diverse, executable, and meaningful tasks directly from the environment structure and affordances, without relying on handcrafted seeds or external corpora. CuES drives exploration through intrinsic curiosity, abstracts interaction patterns into reusable task schemas, and refines them through lightweight top down guidance and memory based quality control. Across three representative environments, AppWorld, BFCL, and WebShop, CuES produces task distributions that match or surpass manually curated datasets in both diversity and executability, yielding substantial downstream policy improvements. These results demonstrate that curiosity driven, environment grounded task generation provides a scalable foundation for agents that not only learn how to act, but also learn what to learn. The code is available at https://github.com/modelscope/AgentEvolver/research/CuES.

Yunpeng Zhai, Shuchang Tao, Cheng Chen et al.

Autonomous agents powered by large language models (LLMs) have the potential to significantly enhance human productivity by reasoning, using tools, and executing complex tasks in diverse environments. However, current approaches to developing such agents remain costly and inefficient, as they typically require manually constructed task datasets and reinforcement learning (RL) pipelines with extensive random exploration. These limitations lead to prohibitively high data-construction costs, low exploration efficiency, and poor sample utilization. To address these challenges, we present AgentEvolver, a self-evolving agent system that leverages the semantic understanding and reasoning capabilities of LLMs to drive autonomous agent learning. AgentEvolver introduces three synergistic mechanisms: (i) self-questioning, which enables curiosity-driven task generation in novel environments, reducing dependence on handcrafted datasets; (ii) self-navigating, which improves exploration efficiency through experience reuse and hybrid policy guidance; and (iii) self-attributing, which enhances sample efficiency by assigning differentiated rewards to trajectory states and actions based on their contribution. By integrating these mechanisms into a unified framework, AgentEvolver enables scalable, cost-effective, and continual improvement of agent capabilities. Preliminary experiments indicate that AgentEvolver achieves more efficient exploration, better sample utilization, and faster adaptation compared to traditional RL-based baselines.

Lipeng Xie, Sen Huang, Zhuo Zhang et al.

Reward models are essential for aligning Large Language Models (LLMs) with human values, yet their development is hampered by costly preference datasets and poor interpretability. While recent rubric-based approaches offer transparency, they often lack systematic quality control and optimization, creating a trade-off between scalability and reliability. We address these limitations with a novel, training-free framework built on a key assumption: \textit{evaluation rubrics underlying human preferences exhibit significant generalization ability across diverse queries}, a property that enables remarkable data efficiency. Our two-stage approach first infers high-quality, query-specific rubrics using a validation-guided \textbf{Propose-Evaluate-Revise} pipeline. Second, it generalizes these granular rubrics into a compact, non-redundant core set by maximizing an \textbf{information-theoretic coding rate}. The final output is an interpretable, hierarchical "Theme-Tips" rubric set. Extensive experiments demonstrate the framework's exceptional data efficiency and performance. Critically, using just 70 preference pairs (1.5\% of the source data), our method also empowers smaller models like Qwen3-8B to outperform specialized, fully-trained counterparts. This work pioneers a scalable, interpretable, and data-efficient path for reward modeling.

Hai Zhao, Hongqiu Wu, Dongjie Yang et al.

We introduce BriLLM, a brain-inspired large language model that fundamentally redefines the foundations of machine learning through its implementation of Signal Fully-connected flowing (SiFu) learning. This work addresses the critical bottleneck hindering AI's progression toward Artificial General Intelligence (AGI)--the disconnect between language models and "world models"--as well as the fundamental limitations of Transformer-based architectures rooted in the conventional representation learning paradigm. BriLLM incorporates two pivotal neurocognitive principles: (1) static semantic mapping, where tokens are mapped to specialized nodes analogous to cortical areas, and (2) dynamic signal propagation, which simulates electrophysiological information dynamics observed in brain activity. This architecture enables multiple transformative breakthroughs: natural multi-modal compatibility, full model interpretability at the node level, context-length independent scaling, and the first global-scale simulation of brain-like information processing for language tasks. Our initial 1-2B parameter models successfully replicate GPT-1-level generative capabilities while demonstrating stable perplexity reduction. Scalability analyses confirm the feasibility of 100-200B parameter variants capable of processing 40,000-token vocabularies. The paradigm is reinforced by both Occam's Razor--evidenced in the simplicity of direct semantic mapping--and natural evolution--given the brain's empirically validated AGI architecture. BriLLM establishes a novel, biologically grounded framework for AGI advancement that addresses fundamental limitations of current approaches.

Anni Zou, Zhuosheng Zhang, Hai Zhao

Commonsense fact verification, as a challenging branch of commonsense question-answering (QA), aims to verify through facts whether a given commonsense claim is correct or not. Answering commonsense questions necessitates a combination of knowledge from various levels. However, existing studies primarily rest on grasping either unstructured evidence or potential reasoning paths from structured knowledge bases, yet failing to exploit the benefits of heterogeneous knowledge simultaneously. In light of this, we propose Decker, a commonsense fact verification model that is capable of bridging heterogeneous knowledge by uncovering latent relationships between structured and unstructured knowledge. Experimental results on two commonsense fact verification benchmark datasets, CSQA2.0 and CREAK demonstrate the effectiveness of our Decker and further analysis verifies its capability to seize more precious information through reasoning.