Hari Bharadwaj

Hamad Ahmed, Ronnie B Wilbur, Hari M Bharadwaj et al.

New results suggest strong limits to the feasibility of classifying human brain activity evoked from image stimuli, as measured through EEG. Considerable prior work suffers from a confound between the stimulus class and the time since the start of the experiment. A prior attempt to avoid this confound using randomized trials was unable to achieve results above chance in a statistically significant fashion when the data sets were of the same size as the original experiments. Here, we again attempt to replicate these experiments with randomized trials on a far larger (20x) dataset of 1,000 stimulus presentations of each of forty classes, all from a single subject. To our knowledge, this is the largest such EEG data collection effort from a single subject and is at the bounds of feasibility. We obtain classification accuracy that is marginally above chance and above chance in a statistically significant fashion, and further assess how accuracy depends on the classifier used, the amount of training data used, and the number of classes. Reaching the limits of data collection without substantial improvement in classification accuracy suggests limits to the feasibility of this enterprise.

Ren Li, Jared S. Johansen, Hamad Ahmed et al.

A recent paper [31] claims to classify brain processing evoked in subjects watching ImageNet stimuli as measured with EEG and to use a representation derived from this processing to create a novel object classifier. That paper, together with a series of subsequent papers [8, 15, 17, 20, 21, 30, 35], claims to revolutionize the field by achieving extremely successful results on several computer-vision tasks, including object classification, transfer learning, and generation of images depicting human perception and thought using brain-derived representations measured through EEG. Our novel experiments and analyses demonstrate that their results crucially depend on the block design that they use, where all stimuli of a given class are presented together, and fail with a rapid-event design, where stimuli of different classes are randomly intermixed. The block design leads to classification of arbitrary brain states based on block-level temporal correlations that tend to exist in all EEG data, rather than stimulus-related activity. Because every trial in their test sets comes from the same block as many trials in the corresponding training sets, their block design thus leads to surreptitiously training on the test set. This invalidates all subsequent analyses performed on this data in multiple published papers and calls into question all of the purported results. We further show that a novel object classifier constructed with a random codebook performs as well as or better than a novel object classifier constructed with the representation extracted from EEG data, suggesting that the performance of their classifier constructed with a representation extracted from EEG data does not benefit at all from the brain-derived representation. Our results calibrate the underlying difficulty of the tasks involved and caution against sensational and overly optimistic, but false, claims to the contrary.

Sheraz Khan, Javeria Hashmi, Fahimeh Mamashli et al.

The functional significance of resting state networks and their abnormal manifestations in psychiatric disorders are firmly established, as is the importance of the cortical rhythms in mediating these networks. Resting state networks are known to undergo substantial reorganization from childhood to adulthood, but whether distinct cortical rhythms, which are generated by separable neural mechanisms and are often manifested abnormally in psychiatric conditions, mediate maturation differentially, remains unknown. Using magnetoencephalography (MEG) to map frequency band specific maturation of resting state networks from age 7 to 29 in 162 participants (31 independent), we found significant changes with age in networks mediated by the beta (13-30Hz) and gamma (31-80Hz) bands. More specifically, gamma band mediated networks followed an expected asymptotic trajectory, but beta band mediated networks followed a linear trajectory. Network integration increased with age in gamma band mediated networks, while local segregation increased with age in beta band mediated networks. Spatially, the hubs that changed in importance with age in the beta band mediated networks had relatively little overlap with those that showed the greatest changes in the gamma band mediated networks. These findings are relevant for our understanding of the neural mechanisms of cortical maturation, in both typical and atypical development.