Kleanthis Marios Papadopoulos

Kleanthis Marios Papadopoulos, Tania Stathaki

The abundance of information present in Whole Slide Images (WSIs) renders them an essential tool for survival analysis. Several Multiple Instance Learning frameworks proposed for this task utilize a ResNet50 backbone pre-trained on natural images. By leveraging recenetly released histopathological foundation models such as UNI and Hibou, the predictive prowess of existing MIL networks can be enhanced. Furthermore, deploying an ensemble of digital pathology foundation models yields higher baseline accuracy, although the benefits appear to diminish with more complex MIL architectures. Our code will be made publicly available upon acceptance.

Nikolaos Giakoumoglou, Andreas Floros, Kleanthis Marios Papadopoulos et al.

This paper does not introduce a novel method per se. Instead, we address the neglected potential of hard negative samples in self-supervised learning. Previous works explored synthetic hard negatives but rarely in the context of vision transformers. We build on this observation and integrate synthetic hard negatives to improve vision transformer representation learning. This simple yet effective technique notably improves the discriminative power of learned representations. Our experiments show performance improvements for both DeiT-S and Swin-T architectures.

Nikolaos Giakoumoglou, Andreas Floros, Kleanthis Marios Papadopoulos et al.

This paper does not introduce a new method per se. Instead, we build on existing self-supervised learning approaches for vision, drawing inspiration from the adage "fake it till you make it". While contrastive self-supervised learning has achieved remarkable success, it typically relies on vast amounts of real-world data and carefully curated hard negatives. To explore alternatives to these requirements, we investigate two forms of "faking it" in vision transformers. First, we study the potential of generative models for unsupervised representation learning, leveraging synthetic data to augment sample diversity. Second, we examine the feasibility of generating synthetic hard negatives in the representation space, creating diverse and challenging contrasts. Our framework - dubbed Syn2Co - combines both approaches and evaluates whether synthetically enhanced training can lead to more robust and transferable visual representations on DeiT-S and Swin-T architectures. Our findings highlight the promise and limitations of synthetic data in self-supervised learning, offering insights for future work in this direction.