Shengjie Yang

Linqing Chen, Weilei Wang, Yubin Xia et al.

In this paper, we propose a novel system that integrates state-of-the-art, domain-specific large language models with advanced information retrieval techniques to deliver comprehensive and context-aware responses. Our approach facilitates seamless interaction among diverse components, enabling cross-validation of outputs to produce accurate, high-quality responses enriched with relevant data, images, tables, and other modalities. We demonstrate the system's capability to enhance response precision by leveraging a robust question-answering model, significantly improving the quality of dialogue generation. The system provides an accessible platform for real-time, high-fidelity interactions, allowing users to benefit from efficient human-computer interaction, precise retrieval, and simultaneous access to a wide range of literature and data. This dramatically improves the research efficiency of professionals in the biomedical and pharmaceutical domains and facilitates faster, more informed decision-making throughout the R\&D process. Furthermore, the system proposed in this paper is available at https://synapse-chat.patsnap.com.

Pinzhuo Tian, Shengjie Yang, Hang Yu et al.

A key human ability is to decompose a scene into distinct objects and use their relationships to understand the environment. Object-centric learning aims to mimic this process in an unsupervised manner. Recently, the slot attention-based framework has emerged as a leading approach in this area and has been widely used in various downstream tasks. However, existing slot attention methods face two key limitations: (1) a lack of high-level semantic information. In current methods, image areas are assigned to slots based on low-level features such as color and texture. This makes the model overly sensitive to low-level features and limits its understanding of object contours, shapes, or other semantic characteristics. (2) The inability to fine-tune the encoder. Current methods require a stable feature space throughout training to enable reconstruction from slots, which restricts the flexibility needed for effective object-centric learning. To address these limitations, we propose a novel ContextFusion stage and a Bootstrap Branch, both of which can be seamlessly integrated into existing slot attention models. In the ContextFusion stage, we exploit semantic information from the foreground and background, incorporating an auxiliary indicator that provides additional contextual cues about them to enrich the semantic content beyond low-level features. In the Bootstrap Branch, we decouple feature adaptation from the original reconstruction phase and introduce a bootstrap strategy to train a feature-adaptive mechanism, allowing for more flexible adaptation. Experimental results show that our method significantly improves the performance of different SOTA slot attention models on both simulated and real-world datasets.

Linqing Chen, Weilei Wang, Zilong Bai et al.

Large language models (LLMs) have revolutionized Natural Language Processing (NLP) by minimizing the need for complex feature engineering. However, the application of LLMs in specialized domains like biopharmaceuticals and chemistry remains largely unexplored. These fields are characterized by intricate terminologies, specialized knowledge, and a high demand for precision areas where general purpose LLMs often fall short. In this study, we introduce PharmaGPT, a suite of domain specilized LLMs with 13 billion and 70 billion parameters, specifically trained on a comprehensive corpus tailored to the Bio-Pharmaceutical and Chemical domains. Our evaluation shows that PharmaGPT surpasses existing general models on specific-domain benchmarks such as NAPLEX, demonstrating its exceptional capability in domain-specific tasks. Remarkably, this performance is achieved with a model that has only a fraction, sometimes just one-tenth-of the parameters of general-purpose large models. This advancement establishes a new benchmark for LLMs in the bio-pharmaceutical and chemical fields, addressing the existing gap in specialized language modeling. It also suggests a promising path for enhanced research and development, paving the way for more precise and effective NLP applications in these areas.