Giosuè Cataldo Marinò

J. Gliozzo, G. Marinò, A. Bonometti et al.

The prediction of tumor progression and chemotherapy response has been recently tackled exploiting Tumor Infiltrating Lymphocytes (TILs) and the nuclear protein Ki67 as prognostic factors. Recently, deep neural networks (DNNs) have been shown to achieve top results in estimating Ki67 expression and simultaneous determination of intratumoral TILs score in breast cancer cells. However, in the last ten years the extraordinary progress induced by deep models proliferated at least as much as their resource demand. The exorbitant computational costs required to query (and in some cases also to store) a deep model represent a strong limitation in resource-limited contexts, like that of IoT-based applications to support healthcare personnel. To this end, we propose a resource consumption-aware DNN for the effective estimate of the percentage of Ki67-positive cells in breast cancer screenings. Our approach reduced up to 75% and 89% the usage of memory and disk space respectively, up to 1.5x the energy consumption, and preserved or improved the overall accuracy of a benchmark state-of-the-art solution. Encouraged by such positive results, we developed and structured the adopted framework so as to allow its general purpose usage, along with a public software repository to support its usage.

Giosuè Cataldo Marinò, Alessandro Petrini, Dario Malchiodi et al.

The state-of-the-art performance for several real-world problems is currently reached by convolutional neural networks (CNN). Such learning models exploit recent results in the field of deep learning, typically leading to highly performing, yet very large neural networks with (at least) millions of parameters. As a result, the deployment of such models is not possible when only small amounts of RAM are available, or in general within resource-limited platforms, and strategies to compress CNNs became thus of paramount importance. In this paper we propose a novel lossless storage format for CNNs based on source coding and leveraging both weight pruning and quantization. We theoretically derive the space upper bounds for the proposed structures, showing their relationship with both sparsity and quantization levels of the weight matrices. Both compression rates and excution times have been tested against reference methods for matrix compression, and an empirical evaluation of state-of-the-art quantization schemes based on weight sharing is also discussed, to assess their impact on the performance when applied to both convolutional and fully connected layers. On four benchmarks for classification and regression problems and comparing to the baseline pre-trained uncompressed network, we achieved a reduction of space occupancy up to 0.6% on fully connected layers and 5.44% on the whole network, while performing at least as competitive as the baseline.

Giosuè Cataldo Marinò, Gregorio Ghidoli, Marco Frasca et al.

Recent advances in deep learning have made available large, powerful convolutional neural networks (CNN) with state-of-the-art performance in several real-world applications. Unfortunately, these large-sized models have millions of parameters, thus they are not deployable on resource-limited platforms (e.g. where RAM is limited). Compression of CNNs thereby becomes a critical problem to achieve memory-efficient and possibly computationally faster model representations. In this paper, we investigate the impact of lossy compression of CNNs by weight pruning and quantization, and lossless weight matrix representations based on source coding. We tested several combinations of these techniques on four benchmark datasets for classification and regression problems, achieving compression rates up to $165$ times, while preserving or improving the model performance.