Jinghang Gu

Qingyu Chen, Alexis Allot, Robert Leaman et al.

The COVID-19 pandemic has been severely impacting global society since December 2019. Massive research has been undertaken to understand the characteristics of the virus and design vaccines and drugs. The related findings have been reported in biomedical literature at a rate of about 10,000 articles on COVID-19 per month. Such rapid growth significantly challenges manual curation and interpretation. For instance, LitCovid is a literature database of COVID-19-related articles in PubMed, which has accumulated more than 200,000 articles with millions of accesses each month by users worldwide. One primary curation task is to assign up to eight topics (e.g., Diagnosis and Treatment) to the articles in LitCovid. Despite the continuing advances in biomedical text mining methods, few have been dedicated to topic annotations in COVID-19 literature. To close the gap, we organized the BioCreative LitCovid track to call for a community effort to tackle automated topic annotation for COVID-19 literature. The BioCreative LitCovid dataset, consisting of over 30,000 articles with manually reviewed topics, was created for training and testing. It is one of the largest multilabel classification datasets in biomedical scientific literature. 19 teams worldwide participated and made 80 submissions in total. Most teams used hybrid systems based on transformers. The highest performing submissions achieved 0.8875, 0.9181, and 0.9394 for macro F1-score, micro F1-score, and instance-based F1-score, respectively. The level of participation and results demonstrate a successful track and help close the gap between dataset curation and method development. The dataset is publicly available via https://ftp.ncbi.nlm.nih.gov/pub/lu/LitCovid/biocreative/ for benchmarking and further development.

Dongling Li, Pengchao Wu, Yuehu Dong et al.

Causal relation extraction of biomedical entities is one of the most complex tasks in biomedical text mining, which involves two kinds of information: entity relations and entity functions. One feasible approach is to take relation extraction and function detection as two independent sub-tasks. However, this separate learning method ignores the intrinsic correlation between them and leads to unsatisfactory performance. In this paper, we propose a joint learning model, which combines entity relation extraction and entity function detection to exploit their commonality and capture their inter-relationship, so as to improve the performance of biomedical causal relation extraction. Meanwhile, during the model training stage, different function types in the loss function are assigned different weights. Specifically, the penalty coefficient for negative function instances increases to effectively improve the precision of function detection. Experimental results on the BioCreative-V Track 4 corpus show that our joint learning model outperforms the separate models in BEL statement extraction, achieving the F1 scores of 58.4% and 37.3% on the test set in Stage 2 and Stage 1 evaluations, respectively. This demonstrates that our joint learning system reaches the state-of-the-art performance in Stage 2 compared with other systems.

Gongchi Chen, Pengchao Wu, Jinghang Gu et al.

In recent years, biomedical event extraction has been dominated by complicated pipeline and joint methods, which need to be simplified. In addition, existing work has not effectively utilized trigger word information explicitly. Hence, we propose MLSL, a method based on multi-layer sequence labeling for joint biomedical event extraction. MLSL does not introduce prior knowledge and complex structures. Moreover, it explicitly incorporates the information of candidate trigger words into the sequence labeling to learn the interaction relationships between trigger words and argument roles. Based on this, MLSL can learn well with just a simple workflow. Extensive experimentation demonstrates the superiority of MLSL in terms of extraction performance compared to other state-of-the-art methods.

Siyuan Liu, Jiahui Xu, Feng Jiang et al.

Achieving human-like responsiveness is a critical yet challenging goal for cascaded spoken dialogue systems. Conventional ASR-LLM-TTS pipelines follow a strictly sequential paradigm, requiring complete transcription and full reasoning before speech synthesis can begin, which results in high response latency. We propose the Discourse-Aware Dual-Track Streaming Response (DDTSR) framework, a low-latency architecture that enables listen-while-thinking and speak-while-thinking. DDTSR is built upon three key mechanisms: (1) connective-guided small-large model synergy, where an auxiliary small model generates minimal-committal discourse connectives while a large model performs knowledge-intensive reasoning in parallel; (2) streaming-based cross-modal collaboration, which dynamically overlaps ASR, LLM inference, and TTS to advance the earliest speakable moment; and (3) curriculum-learning-based discourse continuity enhancement, which maintains coherence and logical consistency between early responses and subsequent reasoning outputs. Experiments on two spoken dialogue benchmarks demonstrate that DDTSR reduces response latency by 19%-51% while preserving discourse quality. Further analysis shows that DDTSR functions as a plug-and-play module compatible with diverse LLM backbones, and remains robust across varying utterance lengths, indicating strong practicality and scalability for real-time spoken interaction.

Xuemei Tang, Chengxi Yan, Jinghang Gu et al.

Despite strong performance on many tasks, large language models (LLMs) show limited ability in historical and cultural reasoning, particularly in non-English contexts such as Chinese history. Taxonomic structures offer an effective mechanism to organize historical knowledge and improve understanding. However, manual taxonomy construction is costly and difficult to scale. Therefore, we propose \textbf{CHisAgent}, a multi-agent LLM framework for historical taxonomy construction in ancient Chinese contexts. CHisAgent decomposes taxonomy construction into three role-specialized stages: a bottom-up \textit{Inducer} that derives an initial hierarchy from raw historical corpora, a top-down \textit{Expander} that introduces missing intermediate concepts using LLM world knowledge, and an evidence-guided \textit{Enricher} that integrates external structured historical resources to ensure faithfulness. Using the \textit{Twenty-Four Histories}, we construct a large-scale, domain-aware event taxonomy covering politics, military, diplomacy, and social life in ancient China. Extensive reference-free and reference-based evaluations demonstrate improved structural coherence and coverage, while further analysis shows that the resulting taxonomy supports cross-cultural alignment.

Xuemei Tang, Chengxi Yan, Jinghang Gu et al.

Chinese information extraction (IE) involves multiple tasks across diverse temporal domains, including Classical and Modern documents. Fine-tuning a single model on heterogeneous tasks and across different eras may lead to interference and reduced performance. Therefore, in this paper, we propose Tea-MOELoRA, a parameter-efficient multi-task framework that combines LoRA with a Mixture-of-Experts (MoE) design. Multiple low-rank LoRA experts specialize in different IE tasks and eras, while a task-era-aware router mechanism dynamically allocates expert contributions. Experiments show that Tea-MOELoRA outperforms both single-task and joint LoRA baselines, demonstrating its ability to leverage task and temporal knowledge effectively.

Pengchao Wu, Xuefeng Li, Jinghang Gu et al.

Biomedical event extraction is an information extraction task to obtain events from biomedical text, whose targets include the type, the trigger, and the respective arguments involved in an event. Traditional biomedical event extraction usually adopts a pipelined approach, which contains trigger identification, argument role recognition, and finally event construction either using specific rules or by machine learning. In this paper, we propose an n-ary relation extraction method based on the BERT pre-training model to construct Binding events, in order to capture the semantic information about an event's context and its participants. The experimental results show that our method achieves promising results on the GE11 and GE13 corpora of the BioNLP shared task with F1 scores of 63.14% and 59.40%, respectively. It demonstrates that by significantly improving theperformance of Binding events, the overall performance of the pipelined event extraction approach or even exceeds those of current joint learning methods.

Xuemei Tang, Jun Wang, Qi Su et al.

Sequence labeling models often benefit from incorporating external knowledge. However, this practice introduces data heterogeneity and complicates the model with additional modules, leading to increased expenses for training a high-performing model. To address this challenge, we propose a two-stage curriculum learning (TCL) framework specifically designed for sequence labeling tasks. The TCL framework enhances training by gradually introducing data instances from easy to hard, aiming to improve both performance and training speed. Furthermore, we explore different metrics for assessing the difficulty levels of sequence labeling tasks. Through extensive experimentation on six Chinese word segmentation (CWS) and Part-of-speech tagging (POS) datasets, we demonstrate the effectiveness of our model in enhancing the performance of sequence labeling models. Additionally, our analysis indicates that TCL accelerates training and alleviates the slow training problem associated with complex models.