Yuxi Zhang

Jiazheng Wang, Xiang Chen, Yuxi Zhang et al.

Surgical navigation based on multimodal image registration has played a significant role in providing intraoperative guidance to surgeons by showing the relative position of the target area to critical anatomical structures during surgery. However, due to the differences between multimodal images and intraoperative image deformation caused by tissue displacement and removal during surgery, effective registration of preoperative and intraoperative multimodal images faces significant challenges. To address the multimodal image registration challenges in Learn2Reg 2024, an unsupervised multimodal medical image registration method based on multilevel correlation balanced optimization (MCBO) is designed to solve these problems. First, the features of each modality are extracted based on the modality independent neighborhood descriptor, and the multimodal images are mapped to the feature space. Second, a multilevel pyramidal fusion optimization mechanism is designed to achieve global optimization and local detail complementation of the deformation field through dense correlation analysis and weight-balanced coupled convex optimization for input features at different scales. For preoperative medical images in different modalities, the alignment and stacking of valid information between different modalities is achieved by the maximum fusion between deformation fields. Our method focuses on the ReMIND2Reg task in Learn2Reg 2024, and to verify the generality of the method, we also tested it on the COMULIS3DCLEM task. Based on the results, our method achieved second place in the validation of both two tasks. The code is available at https://github.com/wjiazheng/MCBO.

Zhengyi Zhao, Shubo Zhang, Yuxi Zhang et al.

Large Language Models (LLMs) have shown impressive capabilities in complex reasoning tasks. However, current approaches employ uniform language density for both intermediate reasoning and final answers, leading to computational inefficiency. Our observation found that reasoning process serves a computational function for the model itself, while answering serves a communicative function for human understanding. This distinction enables the use of compressed, symbol-rich language for intermediate computations while maintaining human-readable final explanations. To address this inefficiency, we present Denser: \underline{D}ual-d\underline{ens}ity inf\underline{er}ence, a novel framework that optimizes information density separately for reasoning and answering phases. Our framework implements this through three components: a query processing module that analyzes input problems, a high-density compressed reasoning mechanism for efficient intermediate computations, and an answer generation component that translates compressed reasoning into human-readable solutions. Experimental evaluation across multiple reasoning question answering benchmarks demonstrates that Denser reduces token consumption by up to 62\% compared to standard Chain-of-Thought methods while preserving or improving accuracy. These efficiency gains are particularly significant for complex multi-step reasoning problems where traditional methods generate extensive explanations.

Hang Zhang, Yuxi Zhang, Jiazheng Wang et al.

Recent developments in neural networks have improved deformable image registration (DIR) by amortizing iterative optimization, enabling fast and accurate DIR results. However, learning-based methods often face challenges with limited training data, large deformations, and tend to underperform compared to iterative approaches when label supervision is unavailable. While iterative methods can achieve higher accuracy in such scenarios, they are considerably slower than learning-based methods. To address these limitations, we propose VoxelOpt, a discrete optimization-based DIR framework that combines the strengths of learning-based and iterative methods to achieve a better balance between registration accuracy and runtime. VoxelOpt uses displacement entropy from local cost volumes to measure displacement signal strength at each voxel, which differs from earlier approaches in three key aspects. First, it introduces voxel-wise adaptive message passing, where voxels with lower entropy receives less influence from their neighbors. Second, it employs a multi-level image pyramid with 27-neighbor cost volumes at each level, avoiding exponential complexity growth. Third, it replaces hand-crafted features or contrastive learning with a pretrained foundational segmentation model for feature extraction. In abdominal CT registration, these changes allow VoxelOpt to outperform leading iterative in both efficiency and accuracy, while matching state-of-the-art learning-based methods trained with label supervision. The source code will be available at https://github.com/tinymilky/VoxelOpt

Yuxi Zhang, Xiang Chen, Jiazheng Wang et al.

In this paper, we summarize the methods and experimental results we proposed for Task 2 in the learn2reg 2024 Challenge. This task focuses on unsupervised registration of anatomical structures in brain MRI images between different patients. The difficulty lies in: (1) without segmentation labels, and (2) a large amount of data. To address these challenges, we built an efficient backbone network and explored several schemes to further enhance registration accuracy. Under the guidance of the NCC loss function and smoothness regularization loss function, we obtained a smooth and reasonable deformation field. According to the leaderboard, our method achieved a Dice coefficient of 77.34%, which is 1.4% higher than the TransMorph. Overall, we won second place on the leaderboard for Task 2.

Xiang Chen, Renjiu Hu, Jinwei Zhang et al.

Learning-based techniques have significantly improved the accuracy and speed of deformable image registration. However, challenges such as reducing computational complexity and handling large deformations persist. To address these challenges, we analyze how convolutional neural networks (ConvNets) influence registration performance using the Horn-Schunck optical flow equation. Supported by prior studies and our empirical experiments, we observe that ConvNets play two key roles in registration: linearizing local intensities and harmonizing global contrast variations. Based on these insights, we propose the Encoder-Only Image Registration (EOIR) framework, designed to achieve a better accuracy-efficiency trade-off. EOIR separates feature learning from flow estimation, employing only a 3-layer ConvNet for feature extraction and a set of 3-layer flow estimators to construct a Laplacian feature pyramid, progressively composing diffeomorphic deformations under a large-deformation model. Results on five datasets across different modalities and anatomical regions demonstrate EOIR's effectiveness, achieving superior accuracy-efficiency and accuracy-smoothness trade-offs. With comparable accuracy, EOIR provides better efficiency and smoothness, and vice versa. The source code of EOIR is publicly available on https://github.com/XiangChen1994/EOIR.

Xin Tian, Jiazheng Wang, Yuxi Zhang et al.

Deformable retinal image registration is notoriously difficult due to large homogeneous regions and sparse but critical vascular features, which cause limited gradient signals in standard learning-based frameworks. In this paper, we introduce Gaussian Primitive Optimization (GPO), a novel iterative framework that performs structured message passing to overcome these challenges. After an initial coarse alignment, we extract keypoints at salient anatomical structures (e.g., major vessels) to serve as a minimal set of descriptor-based control nodes (DCN). Each node is modelled as a Gaussian primitive with trainable position, displacement, and radius, thus adapting its spatial influence to local deformation scales. A K-Nearest Neighbors (KNN) Gaussian interpolation then blends and propagates displacement signals from these information-rich nodes to construct a globally coherent displacement field; focusing interpolation on the top (K) neighbors reduces computational overhead while preserving local detail. By strategically anchoring nodes in high-gradient regions, GPO ensures robust gradient flow, mitigating vanishing gradient signal in textureless areas. The framework is optimized end-to-end via a multi-term loss that enforces both keypoint consistency and intensity alignment. Experiments on the FIRE dataset show that GPO reduces the target registration error from 6.2\,px to ~2.4\,px and increases the AUC at 25\,px from 0.770 to 0.938, substantially outperforming existing methods. The source code can be accessed via https://github.com/xintian-99/GPOreg.

Zhou Tang, Jin Wang, Angelo De Castro et al.

Body condition score (BCS) is a widely used indicator of body energy status and is closely associated with metabolic status, reproductive performance, and health in dairy cattle; however, conventional visual scoring is subjective and labor-intensive. Computer vision approaches have been applied to BCS prediction, with depth images widely used because they capture geometric information independent of coat color and texture. More recently, three-dimensional point cloud data have attracted increasing interest due to their ability to represent richer geometric characteristics of animal morphology, but direct head-to-head comparisons with depth image-based approaches remain limited. In this study, we compared top-view depth image and point cloud data for BCS prediction under four settings: 1) unsegmented raw data, 2) segmented full-body data, 3) segmented hindquarter data, and 4) handcrafted feature data. Prediction models were evaluated using data from 1,020 dairy cows collected on a commercial farm, with cow-level cross-validation to prevent data leakage. Depth image-based models consistently achieved higher accuracy than point cloud-based models when unsegmented raw data and segmented full-body data were used, whereas comparable performance was observed when segmented hindquarter data were used. Both depth image and point cloud approaches showed reduced accuracy when handcrafted feature data were employed compared with the other settings. Overall, point cloud-based predictions were more sensitive to noise and model architecture than depth image-based predictions. Taken together, these results indicate that three-dimensional point clouds do not provide a consistent advantage over depth images for BCS prediction in dairy cattle under the evaluated conditions.

Zhengyi Zhao, Shubo Zhang, Zezhong Wang et al.

Retrieval-Augmented Generation (RAG) significantly enhances Large Language Models (LLMs) by providing access to external knowledge. However, current research primarily focuses on retrieval quality, often overlooking the critical ''integration bottleneck'': even when relevant documents are retrieved, LLMs frequently fail to utilize them effectively due to conflicts with their internal parametric knowledge. In this paper, we argue that implicitly resolving this conflict in a single generation pass is suboptimal. We introduce GuarantRAG, a framework that explicitly decouples reasoning from evidence integration. First, we generate an ''Inner-Answer'' based solely on parametric knowledge to capture the model's reasoning flow. Second, to guarantee faithful evidence extraction, we generate a ''Refer-Answer'' using a novel Contrastive DPO objective. This objective treats the parametric Inner-Answer as a negative constraint and the retrieved documents as positive ground truth, forcing the model to suppress internal hallucinations in favor of external evidence during this phase. Finally, rather than naive concatenation or using the DPO trained model directly, we propose a joint decoding mechanism that dynamically fuses the logical coherence of the Inner-Answer with the factual precision of the Refer-Answer at the token level. Experiments on five QA benchmarks demonstrate that GuarantRAG improves accuracy by up to 12.1% and reduces hallucinations by 16.3% compared to standard and dynamic RAG baselines.

Lasse Hansen, Wiebke Heyer, Christoph Großbröhmer et al.

Medical image registration is critical for clinical applications, and fair benchmarking of different methods is essential for monitoring ongoing progress. To date, the Learn2Reg 2020-2023 challenges have released several complementary datasets and established metrics for evaluations. However, these editions did not capture all aspects of the registration problem, particularly in terms of modality diversity and task complexity. To address these limitations, the 2024 edition introduces three new tasks, including large-scale multi-modal registration and unsupervised inter-subject brain registration, as well as the first microscopy-focused benchmark within Learn2Reg. The new datasets also inspired new method developments, including invertibility constraints, pyramid features, keypoints alignment and instance optimisation.

Zhongsheng Wang, Sijie Wang, Jia Wang et al.

In the design of customer relationship management (CRM) systems, accurately identifying customer types and offering personalized services are key to enhancing customer satisfaction and loyalty. However, this process faces the challenge of discerning customer voices and intentions, and general pre-trained automatic speech recognition (ASR) models make it difficult to effectively address industry-specific speech recognition tasks. To address this issue, we innovatively proposed a solution for fine-tuning industry-specific ASR models, which significantly improved the performance of the fine-tuned ASR models in industry applications. Experimental results show that our method substantially improves the crucial auxiliary role of the ASR model in industry CRM systems, and this approach has also been adopted in actual industrial applications.

Yuxi Zhang, Yueting Li, Xinyu Du et al.

Generating images from rhetorical languages remains a critical challenge for text-to-image models. Even state-of-the-art (SOTA) multimodal large language models (MLLM) fail to generate images based on the hidden meaning inherent in rhetorical language--despite such content being readily mappable to visual representations by humans. A key limitation is that current models emphasize object-level word embedding alignment, causing metaphorical expressions to steer image generation towards their literal visuals and overlook the intended semantic meaning. To address this, we propose Rhet2Pix, a framework that formulates rhetorical text-to-image generation as a multi-step policy optimization problem, incorporating a two-layer MDP diffusion module. In the outer layer, Rhet2Pix converts the input prompt into incrementally elaborated sub-sentences and executes corresponding image-generation actions, constructing semantically richer visuals. In the inner layer, Rhet2Pix mitigates reward sparsity during image generation by discounting the final reward and optimizing every adjacent action pair along the diffusion denoising trajectory. Extensive experiments demonstrate the effectiveness of Rhet2Pix in rhetorical text-to-image generation. Our model outperforms SOTA MLLMs such as GPT-4o, Grok-3 and leading academic baselines across both qualitative and quantitative evaluations. The code and dataset used in this work are publicly available.

Zhengyi Zhao, Shubo Zhang, Yuxi Zhang et al.

Memes have emerged as a popular form of multimodal online communication, where their interpretation heavily depends on the specific context in which they appear. Current approaches predominantly focus on isolated meme analysis, either for harmful content detection or standalone interpretation, overlooking a fundamental challenge: the same meme can express different intents depending on its conversational context. This oversight creates an evaluation gap: although humans intuitively recognize how context shapes meme interpretation, Large Vision Language Models (LVLMs) can hardly understand context-dependent meme intent. To address this critical limitation, we introduce MemeReaCon, a novel benchmark specifically designed to evaluate how LVLMs understand memes in their original context. We collected memes from five different Reddit communities, keeping each meme's image, the post text, and user comments together. We carefully labeled how the text and meme work together, what the poster intended, how the meme is structured, and how the community responded. Our tests with leading LVLMs show a clear weakness: models either fail to interpret critical information in the contexts, or overly focus on visual details while overlooking communicative purpose. MemeReaCon thus serves both as a diagnostic tool exposing current limitations and as a challenging benchmark to drive development toward more sophisticated LVLMs of the context-aware understanding.

Risheng Liu, Yuxi Zhang, Shichao Cheng et al.

Compressed Sensing Magnetic Resonance Imaging (CS-MRI) significantly accelerates MR data acquisition at a sampling rate much lower than the Nyquist criterion. A major challenge for CS-MRI lies in solving the severely ill-posed inverse problem to reconstruct aliasing-free MR images from the sparse k-space data. Conventional methods typically optimize an energy function, producing reconstruction of high quality, but their iterative numerical solvers unavoidably bring extremely slow processing. Recent data-driven techniques are able to provide fast restoration by either learning direct prediction to final reconstruction or plugging learned modules into the energy optimizer. Nevertheless, these data-driven predictors cannot guarantee the reconstruction following constraints underlying the regularizers of conventional methods so that the reliability of their reconstruction results are questionable. In this paper, we propose a converged deep framework assembling principled modules for CS-MRI that fuses learning strategy with the iterative solver of a conventional reconstruction energy. This framework embeds an optimal condition checking mechanism, fostering \emph{efficient} and \emph{reliable} reconstruction. We also apply the framework to two practical tasks, \emph{i.e.}, parallel imaging and reconstruction with Rician noise. Extensive experiments on both benchmark and manufacturer-testing images demonstrate that the proposed method reliably converges to the optimal solution more efficiently and accurately than the state-of-the-art in various scenarios.

Risheng Liu, Long Ma, Yuxi Zhang et al.

Enhancing visual qualities for underexposed images is an extensively concerned task that plays important roles in various areas of multimedia and computer vision. Most existing methods often fail to generate high-quality results with appropriate luminance and abundant details. To address these issues, we in this work develop a novel framework, integrating both knowledge from physical principles and implicit distributions from data to solve the underexposed image correction task. More concretely, we propose a new perspective to formulate this task as an energy-inspired model with advanced hybrid priors. A propagation procedure navigated by the hybrid priors is well designed for simultaneously propagating the reflectance and illumination toward desired results. We conduct extensive experiments to verify the necessity of integrating both underlying principles (i.e., with knowledge) and distributions (i.e., from data) as navigated deep propagation. Plenty of experimental results of underexposed image correction demonstrate that our proposed method performs favorably against the state-of-the-art methods on both subjective and objective assessments. Additionally, we execute the task of face detection to further verify the naturalness and practical value of underexposed image correction. What's more, we employ our method to single image haze removal whose experimental results further demonstrate its superiorities.

Risheng Liu, Yuxi Zhang, Shichao Cheng et al.

Magnetic Resonance Imaging (MRI) is one of the most dynamic and safe imaging techniques available for clinical applications. However, the rather slow speed of MRI acquisitions limits the patient throughput and potential indi cations. Compressive Sensing (CS) has proven to be an efficient technique for accelerating MRI acquisition. The most widely used CS-MRI model, founded on the premise of reconstructing an image from an incompletely filled k-space, leads to an ill-posed inverse problem. In the past years, lots of efforts have been made to efficiently optimize the CS-MRI model. Inspired by deep learning techniques, some preliminary works have tried to incorporate deep architectures into CS-MRI process. Unfortunately, the convergence issues (due to the experience-based networks) and the robustness (i.e., lack real-world noise modeling) of these deeply trained optimization methods are still missing. In this work, we develop a new paradigm to integrate designed numerical solvers and the data-driven architectures for CS-MRI. By introducing an optimal condition checking mechanism, we can successfully prove the convergence of our established deep CS-MRI optimization scheme. Furthermore, we explicitly formulate the Rician noise distributions within our framework and obtain an extended CS-MRI network to handle the real-world nosies in the MRI process. Extensive experimental results verify that the proposed paradigm outperforms the existing state-of-the-art techniques both in reconstruction accuracy and efficiency as well as robustness to noises in real scene.