Xi Jia

Siyang Song, Yuxin Song, Cheng Luo et al.

Graph is powerful for representing various types of real-world data. The topology (edges' presence) and edges' features of a graph decides the message passing mechanism among vertices within the graph. While most existing approaches only manually define a single-value edge to describe the connectivity or strength of association between a pair of vertices, task-specific and crucial relationship cues may be disregarded by such manually defined topology and single-value edge features. In this paper, we propose the first general graph representation learning framework (called GRATIS) which can generate a strong graph representation with a task-specific topology and task-specific multi-dimensional edge features from any arbitrary input. To learn each edge's presence and multi-dimensional feature, our framework takes both of the corresponding vertices pair and their global contextual information into consideration, enabling the generated graph representation to have a globally optimal message passing mechanism for different down-stream tasks. The principled investigation results achieved for various graph analysis tasks on 11 graph and non-graph datasets show that our GRATIS can not only largely enhance pre-defined graphs but also learns a strong graph representation for non-graph data, with clear performance improvements on all tasks. In particular, the learned topology and multi-dimensional edge features provide complementary task-related cues for graph analysis tasks. Our framework is effective, robust and flexible, and is a plug-and-play module that can be combined with different backbones and Graph Neural Networks (GNNs) to generate a task-specific graph representation from various graph and non-graph data. Our code is made publicly available at https://github.com/SSYSteve/Learning-Graph-Representation-with-Task-specific-Topology-and-Multi-dimensional-Edge-Features.

Xi Jia, Alexander Thorley, Alberto Gomez et al.

U-Net style networks are commonly utilized in unsupervised image registration to predict dense displacement fields, which for high-resolution volumetric image data is a resource-intensive and time-consuming task. To tackle this challenge, we first propose Fourier-Net, which replaces the costly U-Net style expansive path with a parameter-free model-driven decoder. Instead of directly predicting a full-resolution displacement field, our Fourier-Net learns a low-dimensional representation of the displacement field in the band-limited Fourier domain which our model-driven decoder converts to a full-resolution displacement field in the spatial domain. Expanding upon Fourier-Net, we then introduce Fourier-Net+, which additionally takes the band-limited spatial representation of the images as input and further reduces the number of convolutional layers in the U-Net style network's contracting path. Finally, to enhance the registration performance, we propose a cascaded version of Fourier-Net+. We evaluate our proposed methods on three datasets, on which our proposed Fourier-Net and its variants achieve comparable results with current state-of-the art methods, while exhibiting faster inference speeds, lower memory footprint, and fewer multiply-add operations. With such small computational cost, our Fourier-Net+ enables the efficient training of large-scale 3D registration on low-VRAM GPUs. Our code is publicly available at \url{https://github.com/xi-jia/Fourier-Net}.

Xi Jia, Joseph Bartlett, Tianyang Zhang et al.

Due to their extreme long-range modeling capability, vision transformer-based networks have become increasingly popular in deformable image registration. We believe, however, that the receptive field of a 5-layer convolutional U-Net is sufficient to capture accurate deformations without needing long-range dependencies. The purpose of this study is therefore to investigate whether U-Net-based methods are outdated compared to modern transformer-based approaches when applied to medical image registration. For this, we propose a large kernel U-Net (LKU-Net) by embedding a parallel convolutional block to a vanilla U-Net in order to enhance the effective receptive field. On the public 3D IXI brain dataset for atlas-based registration, we show that the performance of the vanilla U-Net is already comparable with that of state-of-the-art transformer-based networks (such as TransMorph), and that the proposed LKU-Net outperforms TransMorph by using only 1.12% of its parameters and 10.8% of its mult-adds operations. We further evaluate LKU-Net on a MICCAI Learn2Reg 2021 challenge dataset for inter-subject registration, our LKU-Net also outperforms TransMorph on this dataset and ranks first on the public leaderboard as of the submission of this work. With only modest modifications to the vanilla U-Net, we show that U-Net can outperform transformer-based architectures on inter-subject and atlas-based 3D medical image registration. Code is available at https://github.com/xi-jia/LKU-Net.

Xi Jia, Joseph Bartlett, Wei Chen et al.

Unsupervised image registration commonly adopts U-Net style networks to predict dense displacement fields in the full-resolution spatial domain. For high-resolution volumetric image data, this process is however resource-intensive and time-consuming. To tackle this problem, we propose the Fourier-Net, replacing the expansive path in a U-Net style network with a parameter-free model-driven decoder. Specifically, instead of our Fourier-Net learning to output a full-resolution displacement field in the spatial domain, we learn its low-dimensional representation in a band-limited Fourier domain. This representation is then decoded by our devised model-driven decoder (consisting of a zero padding layer and an inverse discrete Fourier transform layer) to the dense, full-resolution displacement field in the spatial domain. These changes allow our unsupervised Fourier-Net to contain fewer parameters and computational operations, resulting in faster inference speeds. Fourier-Net is then evaluated on two public 3D brain datasets against various state-of-the-art approaches. For example, when compared to a recent transformer-based method, named TransMorph, our Fourier-Net, which only uses 2.2\% of its parameters and 6.66\% of the multiply-add operations, achieves a 0.5\% higher Dice score and an 11.48 times faster inference speed. Code is available at \url{https://github.com/xi-jia/Fourier-Net}.

Qiufu Li, Xi Jia, Jiancan Zhou et al.

Sample-to-class-based face recognition models can not fully explore the cross-sample relationship among large amounts of facial images, while sample-to-sample-based models require sophisticated pairing processes for training. Furthermore, neither method satisfies the requirements of real-world face verification applications, which expect a unified threshold separating positive from negative facial pairs. In this paper, we propose a unified threshold integrated sample-to-sample based loss (USS loss), which features an explicit unified threshold for distinguishing positive from negative pairs. Inspired by our USS loss, we also derive the sample-to-sample based softmax and BCE losses, and discuss their relationship. Extensive evaluation on multiple benchmark datasets, including MFR, IJB-C, LFW, CFP-FP, AgeDB, and MegaFace, demonstrates that the proposed USS loss is highly efficient and can work seamlessly with sample-to-class-based losses. The embedded loss (USS and sample-to-class Softmax loss) overcomes the pitfalls of previous approaches and the trained facial model UniTSFace exhibits exceptional performance, outperforming state-of-the-art methods, such as CosFace, ArcFace, VPL, AnchorFace, and UNPG. Our code is available.

Xinxing Cheng, Xi Jia, Wenqi Lu et al.

Deep image registration has demonstrated exceptional accuracy and fast inference. Recent advances have adopted either multiple cascades or pyramid architectures to estimate dense deformation fields in a coarse-to-fine manner. However, due to the cascaded nature and repeated composition/warping operations on feature maps, these methods negatively increase memory usage during training and testing. Moreover, such approaches lack explicit constraints on the learning process of small deformations at different scales, thus lacking explainability. In this study, we introduce a model-driven WiNet that incrementally estimates scale-wise wavelet coefficients for the displacement/velocity field across various scales, utilizing the wavelet coefficients derived from the original input image pair. By exploiting the properties of the wavelet transform, these estimated coefficients facilitate the seamless reconstruction of a full-resolution displacement/velocity field via our devised inverse discrete wavelet transform (IDWT) layer. This approach avoids the complexities of cascading networks or composition operations, making our WiNet an explainable and efficient competitor with other coarse-to-fine methods. Extensive experimental results from two 3D datasets show that our WiNet is accurate and GPU efficient. The code is available at https://github.com/x-xc/WiNet .

Wei Chen, Xi Jia, Zhongqun Zhang et al.

In this paper, we propose a novel 3D graph convolution based pipeline for category-level 6D pose and size estimation from monocular RGB-D images. The proposed method leverages an efficient 3D data augmentation and a novel vector-based decoupled rotation representation. Specifically, we first design an orientation-aware autoencoder with 3D graph convolution for latent feature learning. The learned latent feature is insensitive to point shift and size thanks to the shift and scale-invariance properties of the 3D graph convolution. Then, to efficiently decode the rotation information from the latent feature, we design a novel flexible vector-based decomposable rotation representation that employs two decoders to complementarily access the rotation information. The proposed rotation representation has two major advantages: 1) decoupled characteristic that makes the rotation estimation easier; 2) flexible length and rotated angle of the vectors allow us to find a more suitable vector representation for specific pose estimation task. Finally, we propose a 3D deformation mechanism to increase the generalization ability of the pipeline. Extensive experiments show that the proposed pipeline achieves state-of-the-art performance on category-level tasks. Further, the experiments demonstrate that the proposed rotation representation is more suitable for the pose estimation tasks than other rotation representations.

Xi Jia, Wenqi Lu, Xinxing Cheng et al.

In unsupervised medical image registration, the predominant approaches involve the utilization of a encoder-decoder network architecture, allowing for precise prediction of dense, full-resolution displacement fields from given paired images. Despite its widespread use in the literature, we argue for the necessity of making both the encoder and decoder learnable in such an architecture. For this, we propose a novel network architecture, termed LessNet in this paper, which contains only a learnable decoder, while entirely omitting the utilization of a learnable encoder. LessNet substitutes the learnable encoder with simple, handcrafted features, eliminating the need to learn (optimize) network parameters in the encoder altogether. Consequently, this leads to a compact, efficient, and decoder-only architecture for 3D medical image registration. Evaluated on two publicly available brain MRI datasets, we demonstrate that our decoder-only LessNet can effectively and efficiently learn both dense displacement and diffeomorphic deformation fields in 3D. Furthermore, our decoder-only LessNet can achieve comparable registration performance to state-of-the-art methods such as VoxelMorph and TransMorph, while requiring significantly fewer computational resources. Our code and pre-trained models are available at https://github.com/xi-jia/LessNet.

Weijia Fan, Jiajun Wen, Xi Jia et al.

Prototype learning is widely used in face recognition, which takes the row vectors of coefficient matrix in the last linear layer of the feature extraction model as the prototypes for each class. When the prototypes are updated using the facial sample feature gradients in the model training, they are prone to being pulled away from the class center by the hard samples, resulting in decreased overall model performance. In this paper, we explicitly define prototypes as the expectations of sample features in each class and design the empirical prototypes using the existing samples in the dataset. We then devise a strategy to adaptively update these empirical prototypes during the model training based on the similarity between the sample features and the empirical prototypes. Furthermore, we propose an empirical prototype learning (EPL) method, which utilizes an adaptive margin parameter with respect to sample features. EPL assigns larger margins to the normal samples and smaller margins to the hard samples, allowing the learned empirical prototypes to better reflect the class center dominated by the normal samples and finally pull the hard samples towards the empirical prototypes through the learning. The extensive experiments on MFR, IJB-C, LFW, CFP-FP, AgeDB, and MegaFace demonstrate the effectiveness of EPL. Our code is available at $\href{https://github.com/WakingHours-GitHub/EPL}{https://github.com/WakingHours-GitHub/EPL}$.

Tianyang Zhang, Shaoming Zheng, Jun Cheng et al.

Generative models have been widely proposed in image recognition to generate more images where the distribution is similar to that of the real ones. It often introduces a discriminator network to differentiate the real data from the generated ones. Such models utilise a discriminator network tasked with differentiating style transferred data from data contained in the target dataset. However in doing so the network focuses on discrepancies in the intensity distribution and may overlook structural differences between the datasets. In this paper we formulate a new image-to-image translation problem to ensure that the structure of the generated images is similar to that in the target dataset. We propose a simple, yet powerful Structure-Unbiased Adversarial (SUA) network which accounts for both intensity and structural differences between the training and test sets when performing image segmentation. It consists of a spatial transformation block followed by an intensity distribution rendering module. The spatial transformation block is proposed to reduce the structure gap between the two images, and also produce an inverse deformation field to warp the final segmented image back. The intensity distribution rendering module then renders the deformed structure to an image with the target intensity distribution. Experimental results show that the proposed SUA method has the capability to transfer both intensity distribution and structural content between multiple datasets.

Weizeng Lu, Xi Jia, Weicheng Xie et al.

We propose a geometry constrained network, termed GC-Net, for weakly supervised object localization (WSOL). GC-Net consists of three modules: a detector, a generator and a classifier. The detector predicts the object location defined by a set of coefficients describing a geometric shape (i.e. ellipse or rectangle), which is geometrically constrained by the mask produced by the generator. The classifier takes the resulting masked images as input and performs two complementary classification tasks for the object and background. To make the mask more compact and more complete, we propose a novel multi-task loss function that takes into account area of the geometric shape, the categorical cross-entropy and the negative entropy. In contrast to previous approaches, GC-Net is trained end-to-end and predict object location without any post-processing (e.g. thresholding) that may require additional tuning. Extensive experiments on the CUB-200-2011 and ILSVRC2012 datasets show that GC-Net outperforms state-of-the-art methods by a large margin. Our source code is available at https://github.com/lwzeng/GC-Net.

Qiufu Li, Xi Jia, Jiancan Zhou et al.

This paper introduces the concept of uniform classification, which employs a unified threshold to classify all samples rather than adaptive threshold classifying each individual sample. We also propose the uniform classification accuracy as a metric to measure the model's performance in uniform classification. Furthermore, begin with a naive loss, we mathematically derive a loss function suitable for the uniform classification, which is the BCE function integrated with a unified bias. We demonstrate the unified threshold could be learned via the bias. The extensive experiments on six classification datasets and three feature extraction models show that, compared to the SoftMax loss, the models trained with the BCE loss not only exhibit higher uniform classification accuracy but also higher sample-wise classification accuracy. In addition, the learned bias from BCE loss is very close to the unified threshold used in the uniform classification. The features extracted by the models trained with BCE loss not only possess uniformity but also demonstrate better intra-class compactness and inter-class distinctiveness, yielding superior performance on open-set tasks such as face recognition.

Lasse Hansen, Wiebke Heyer, Christoph Großbröhmer et al.

Medical image registration is critical for clinical applications, and fair benchmarking of different methods is essential for monitoring ongoing progress. To date, the Learn2Reg 2020-2023 challenges have released several complementary datasets and established metrics for evaluations. However, these editions did not capture all aspects of the registration problem, particularly in terms of modality diversity and task complexity. To address these limitations, the 2024 edition introduces three new tasks, including large-scale multi-modal registration and unsupervised inter-subject brain registration, as well as the first microscopy-focused benchmark within Learn2Reg. The new datasets also inspired new method developments, including invertibility constraints, pyramid features, keypoints alignment and instance optimisation.

Wiebke Heyer, Yannic Elser, Lennart Berkel et al.

In modern cancer research, the vast volume of medical data generated is often underutilised due to challenges related to patient privacy. The OncoReg Challenge addresses this issue by enabling researchers to develop and validate image registration methods through a two-phase framework that ensures patient privacy while fostering the development of more generalisable AI models. Phase one involves working with a publicly available dataset, while phase two focuses on training models on a private dataset within secure hospital networks. OncoReg builds upon the foundation established by the Learn2Reg Challenge by incorporating the registration of interventional cone-beam computed tomography (CBCT) with standard planning fan-beam CT (FBCT) images in radiotherapy. Accurate image registration is crucial in oncology, particularly for dynamic treatment adjustments in image-guided radiotherapy, where precise alignment is necessary to minimise radiation exposure to healthy tissues while effectively targeting tumours. This work details the methodology and data behind the OncoReg Challenge and provides a comprehensive analysis of the competition entries and results. Findings reveal that feature extraction plays a pivotal role in this registration task. A new method emerging from this challenge demonstrated its versatility, while established approaches continue to perform comparably to newer techniques. Both deep learning and classical approaches still play significant roles in image registration, with the combination of methods, particularly in feature extraction, proving most effective.

Alexander Thorley, Xi Jia, Hyung Jin Chang et al.

Deterministic approaches using iterative optimisation have been historically successful in diffeomorphic image registration (DiffIR). Although these approaches are highly accurate, they typically carry a significant computational burden. Recent developments in stochastic approaches based on deep learning have achieved sub-second runtimes for DiffIR with competitive registration accuracy, offering a fast alternative to conventional iterative methods. In this paper, we attempt to reduce this difference in speed whilst retaining the performance advantage of iterative approaches in DiffIR. We first propose a simple iterative scheme that functionally composes intermediate non-stationary velocity fields to handle large deformations in images whilst guaranteeing diffeomorphisms in the resultant deformation. We then propose a convex optimisation model that uses a regularisation term of arbitrary order to impose smoothness on these velocity fields and solve this model with a fast algorithm that combines Nesterov gradient descent and the alternating direction method of multipliers (ADMM). Finally, we leverage the computational power of GPU to implement this accelerated ADMM solver on a 3D cardiac MRI dataset, further reducing runtime to less than 2 seconds. In addition to producing strictly diffeomorphic deformations, our methods outperform both state-of-the-art deep learning-based and iterative DiffIR approaches in terms of dice and Hausdorff scores, with speed approaching the inference time of deep learning-based methods.

Xi Jia, Alexander Thorley, Wei Chen et al.

Data-driven deep learning approaches to image registration can be less accurate than conventional iterative approaches, especially when training data is limited. To address this whilst retaining the fast inference speed of deep learning, we propose VR-Net, a novel cascaded variational network for unsupervised deformable image registration. Using the variable splitting optimization scheme, we first convert the image registration problem, established in a generic variational framework, into two sub-problems, one with a point-wise, closed-form solution while the other one is a denoising problem. We then propose two neural layers (i.e. warping layer and intensity consistency layer) to model the analytical solution and a residual U-Net to formulate the denoising problem (i.e. generalized denoising layer). Finally, we cascade the warping layer, intensity consistency layer, and generalized denoising layer to form the VR-Net. Extensive experiments on three (two 2D and one 3D) cardiac magnetic resonance imaging datasets show that VR-Net outperforms state-of-the-art deep learning methods on registration accuracy, while maintains the fast inference speed of deep learning and the data-efficiency of variational model.

Wei Chen, Xi Jia, Hyung Jin Chang et al.

In this paper, we focus on category-level 6D pose and size estimation from monocular RGB-D image. Previous methods suffer from inefficient category-level pose feature extraction which leads to low accuracy and inference speed. To tackle this problem, we propose a fast shape-based network (FS-Net) with efficient category-level feature extraction for 6D pose estimation. First, we design an orientation aware autoencoder with 3D graph convolution for latent feature extraction. The learned latent feature is insensitive to point shift and object size thanks to the shift and scale-invariance properties of the 3D graph convolution. Then, to efficiently decode category-level rotation information from the latent feature, we propose a novel decoupled rotation mechanism that employs two decoders to complementarily access the rotation information. Meanwhile, we estimate translation and size by two residuals, which are the difference between the mean of object points and ground truth translation, and the difference between the mean size of the category and ground truth size, respectively. Finally, to increase the generalization ability of FS-Net, we propose an online box-cage based 3D deformation mechanism to augment the training data. Extensive experiments on two benchmark datasets show that the proposed method achieves state-of-the-art performance in both category- and instance-level 6D object pose estimation. Especially in category-level pose estimation, without extra synthetic data, our method outperforms existing methods by 6.3% on the NOCS-REAL dataset.

Wei Chen, Xi Jia, Hyung Jin Chang et al.

In this paper, we propose a novel real-time 6D object pose estimation framework, named G2L-Net. Our network operates on point clouds from RGB-D detection in a divide-and-conquer fashion. Specifically, our network consists of three steps. First, we extract the coarse object point cloud from the RGB-D image by 2D detection. Second, we feed the coarse object point cloud to a translation localization network to perform 3D segmentation and object translation prediction. Third, via the predicted segmentation and translation, we transfer the fine object point cloud into a local canonical coordinate, in which we train a rotation localization network to estimate initial object rotation. In the third step, we define point-wise embedding vector features to capture viewpoint-aware information. To calculate more accurate rotation, we adopt a rotation residual estimator to estimate the residual between initial rotation and ground truth, which can boost initial pose estimation performance. Our proposed G2L-Net is real-time despite the fact multiple steps are stacked via the proposed coarse-to-fine framework. Extensive experiments on two benchmark datasets show that G2L-Net achieves state-of-the-art performance in terms of both accuracy and speed.

WenTing Chen, Xinpeng Xie, Xi Jia et al.

Despite the significant success in image-to-image translation and latent representation based facial attribute editing and expression synthesis, the existing approaches still have limitations in the sharpness of details, distinct image translation and identity preservation. To address these issues, we propose a Texture Deformation Based GAN, namely TDB-GAN, to disentangle texture from original image and transfers domains based on the extracted texture. The approach utilizes the texture to transfer facial attributes and expressions without the consideration of the object pose. This leads to shaper details and more distinct visual effect of the synthesized faces. In addition, it brings the faster convergence during training. The effectiveness of the proposed method is validated through extensive ablation studies. We also evaluate our approach qualitatively and quantitatively on facial attribute and facial expression synthesis. The results on both the CelebA and RaFD datasets suggest that Texture Deformation Based GAN achieves better performance.

Xi Jia, Linlin Shen

We proposed a two stage framework with only one network to analyze skin lesion images, we firstly trained a convolutional network to classify these images, and cropped the import regions which the network has the maximum activation value. In the second stage, we retrained this CNN with the image regions extracted from stage one and output the final probabilities. The two stage framework achieved a mean AUC of 0.857 in ISIC-2017 skin lesion validation set and is 0.04 higher than that of the original inputs, 0.821.