95.5HCMay 16
Human-LLM Compound System for Scientific Ideation through Facet Recombination and Novelty EvaluationMarissa Radensky, Simra Shahid, Raymond Fok et al. · allen-ai, uw
The scientific ideation process often involves blending facets of existing papers to create new ideas. We contribute Scideator, the first human-LLM system for facet-based scientific ideation. Starting from user-provided papers, Scideator extracts key facets -- purposes, mechanisms, and evaluations -- from these and related papers, allowing users to interactively recombine facets to synthesize ideas. Scideator is driven by three design choices: (1) human-in-the-loop facet recombination, in which users select facets from retrieved papers and the system generates ideas by finding analogies across them via the Faceted Idea Generator module; (2) distance-controlled retrieval via the Analogous Paper Facet Finder module, which surfaces papers ranging from the same topic to entirely different areas to provide a spectrum of directions; and (3) facet-based novelty verification via the Idea Novelty Checker module, a retrieve-then-rerank pipeline that helps users to evaluate idea originality using facets. In a user study with computer science researchers, Scideator provided significantly more creativity support than a baseline using the same backbone LLM without our facet-based modules, particularly in idea exploration and expressiveness. Ablations further show that the facets benefit the novelty checker: facet-based retrieve-then-rerank surfaces more relevant papers than standard retrieval and re-ranking, and a facet-grounded novelty classifier outperforms classifiers that reason over unstructured ideas and papers.
CLMay 4, 2022
A Computational Inflection for Scientific DiscoveryTom Hope, Doug Downey, Oren Etzioni et al. · uw
We stand at the foot of a significant inflection in the trajectory of scientific discovery. As society continues on its fast-paced digital transformation, so does humankind's collective scientific knowledge and discourse. We now read and write papers in digitized form, and a great deal of the formal and informal processes of science are captured digitally -- including papers, preprints and books, code and datasets, conference presentations, and interactions in social networks and collaboration and communication platforms. The transition has led to the creation and growth of a tremendous amount of information -- much of which is available for public access -- opening exciting opportunities for computational models and systems that analyze and harness it. In parallel, exponential growth in data processing power has fueled remarkable advances in artificial intelligence, including large neural language models capable of learning powerful representations from unstructured text. Dramatic changes in scientific communication -- such as the advent of the first scientific journal in the 17th century -- have historically catalyzed revolutions in scientific thought. The confluence of societal and computational trends suggests that computer science is poised to ignite a revolution in the scientific process itself.
HCSep 23, 2024
Human-LLM Compound System for Scientific Ideation through Facet Recombination and Novelty EvaluationMarissa Radensky, Simra Shahid, Raymond Fok et al. · allen-ai, uw
The scientific ideation process often involves blending salient aspects of existing papers to create new ideas - a framework known as facet-based ideation. We contribute Scideator, the first human-LLM system for facet-based scientific ideation. Starting from a user-provided set of scientific papers, Scideator extracts key facets -- purposes, mechanisms, and evaluations -- from these and related papers, allowing users to explore the idea space by interactively recombining facets to synthesize inventive ideas. Scideator is driven by three design choices: (1) human-in-the-loop facet recombination, in which users select facets from retrieved papers and the system generates ideas by finding analogies across them via the Faceted Idea Generator module; (2) distance-controlled retrieval via the Analogous Paper Facet Finder module, which surfaces papers from the same topic to entirely different subareas to provide a spectrum of creative directions; and (3) facet-based novelty verification via the Idea Novelty Checker module, a retrieve-then-rerank pipeline that evaluates idea originality using facets. In a user study with computer science researchers, Scideator provided significantly more creativity support than a baseline using the same backbone LLM without our facet-based modules, particularly in idea exploration and expressiveness. Participants' favorite ideas more often included facets selected by themselves rather than the LLM, and participants used fewer free-text instructions with Scideator, indicating a preference for facet-level steering over prompting. Finally, re-ranking papers by facet matching rather than general relevance improved novelty classification accuracy from 13.79% to 89.66%.
CLMay 4, 2022
A Dataset for N-ary Relation Extraction of Drug CombinationsAryeh Tiktinsky, Vijay Viswanathan, Danna Niezni et al. · cmu
Combination therapies have become the standard of care for diseases such as cancer, tuberculosis, malaria and HIV. However, the combinatorial set of available multi-drug treatments creates a challenge in identifying effective combination therapies available in a situation. To assist medical professionals in identifying beneficial drug-combinations, we construct an expert-annotated dataset for extracting information about the efficacy of drug combinations from the scientific literature. Beyond its practical utility, the dataset also presents a unique NLP challenge, as the first relation extraction dataset consisting of variable-length relations. Furthermore, the relations in this dataset predominantly require language understanding beyond the sentence level, adding to the challenge of this task. We provide a promising baseline model and identify clear areas for further improvement. We release our dataset, code, and baseline models publicly to encourage the NLP community to participate in this task.
AIJun 19, 2023
SynerGPT: In-Context Learning for Personalized Drug Synergy Prediction and Drug DesignCarl Edwards, Aakanksha Naik, Tushar Khot et al. · cmu
Predicting synergistic drug combinations can help accelerate discovery of cancer treatments, particularly therapies personalized to a patient's specific tumor via biopsied cells. In this paper, we propose a novel setting and models for in-context drug synergy learning. We are given a small "personalized dataset" of 10-20 drug synergy relationships in the context of specific cancer cell targets. Our goal is to predict additional drug synergy relationships in that context. Inspired by recent work that pre-trains a GPT language model (LM) to "in-context learn" common function classes, we devise novel pre-training schemes that enable a GPT model to in-context learn "drug synergy functions". Our model -- which does not use any textual corpora, molecular fingerprints, protein interaction or any other domain-specific knowledge -- is able to achieve competitive results. We further integrate our in-context approach with a genetic algorithm to optimize model prompts and select synergy candidates to test after conducting a patient biopsy. Finally, we explore a novel task of inverse drug design which can potentially enable the design of drugs that synergize specifically to target a given patient's "personalized dataset". Our findings can potentially have an important impact on precision cancer medicine, and also raise intriguing questions on non-textual pre-training for LMs.
CLMay 14, 2022
ACCoRD: A Multi-Document Approach to Generating Diverse Descriptions of Scientific ConceptsSonia K. Murthy, Kyle Lo, Daniel King et al. · allen-ai, uw
Systems that can automatically define unfamiliar terms hold the promise of improving the accessibility of scientific texts, especially for readers who may lack prerequisite background knowledge. However, current systems assume a single "best" description per concept, which fails to account for the many potentially useful ways a concept can be described. We present ACCoRD, an end-to-end system tackling the novel task of generating sets of descriptions of scientific concepts. Our system takes advantage of the myriad ways a concept is mentioned across the scientific literature to produce distinct, diverse descriptions of target scientific concepts in terms of different reference concepts. To support research on the task, we release an expert-annotated resource, the ACCoRD corpus, which includes 1,275 labeled contexts and 1,787 hand-authored concept descriptions. We conduct a user study demonstrating that (1) users prefer descriptions produced by our end-to-end system, and (2) users prefer multiple descriptions to a single "best" description.
CLMay 16, 2022Code
CascadER: Cross-Modal Cascading for Knowledge Graph Link PredictionTara Safavi, Doug Downey, Tom Hope
Knowledge graph (KG) link prediction is a fundamental task in artificial intelligence, with applications in natural language processing, information retrieval, and biomedicine. Recently, promising results have been achieved by leveraging cross-modal information in KGs, using ensembles that combine knowledge graph embeddings (KGEs) and contextual language models (LMs). However, existing ensembles are either (1) not consistently effective in terms of ranking accuracy gains or (2) impractically inefficient on larger datasets due to the combinatorial explosion problem of pairwise ranking with deep language models. In this paper, we propose a novel tiered ranking architecture CascadER to maintain the ranking accuracy of full ensembling while improving efficiency considerably. CascadER uses LMs to rerank the outputs of more efficient base KGEs, relying on an adaptive subset selection scheme aimed at invoking the LMs minimally while maximizing accuracy gain over the KGE. Extensive experiments demonstrate that CascadER improves MRR by up to 9 points over KGE baselines, setting new state-of-the-art performance on four benchmarks while improving efficiency by one or more orders of magnitude over competitive cross-modal baselines. Our empirical analyses reveal that diversity of models across modalities and preservation of individual models' confidence signals help explain the effectiveness of CascadER, and suggest promising directions for cross-modal cascaded architectures. Code and pretrained models are available at https://github.com/tsafavi/cascader.
CLJun 21, 2023
ARIES: A Corpus of Scientific Paper Edits Made in Response to Peer ReviewsMike D'Arcy, Alexis Ross, Erin Bransom et al. · allen-ai
We introduce the task of automatically revising scientific papers based on peer feedback and release ARIES, a dataset of review comments and their corresponding paper edits. The data is drawn from real reviewer-author interactions from computer science, and we provide labels linking each reviewer comment to the specific paper edits made by the author in response. We automatically create a high-precision silver training set, as well as an expert-labeled test set that shows high inter-annotator agreement. In experiments with 10 models covering the state of the art, we find that they struggle even to identify which edits correspond to a comment -- especially when the relationship between the edit and the comment is indirect and requires reasoning to uncover. We also extensively analyze GPT-4's ability to generate edits given a comment and the original paper. We find that it often succeeds on a superficial level, but tends to rigidly follow the wording of the feedback rather than the underlying intent, and lacks technical details compared to human-written edits.
CLNov 19, 2023Code
CHAMP: Efficient Annotation and Consolidation of Cluster HierarchiesArie Cattan, Tom Hope, Doug Downey et al.
Various NLP tasks require a complex hierarchical structure over nodes, where each node is a cluster of items. Examples include generating entailment graphs, hierarchical cross-document coreference resolution, annotating event and subevent relations, etc. To enable efficient annotation of such hierarchical structures, we release CHAMP, an open source tool allowing to incrementally construct both clusters and hierarchy simultaneously over any type of texts. This incremental approach significantly reduces annotation time compared to the common pairwise annotation approach and also guarantees maintaining transitivity at the cluster and hierarchy levels. Furthermore, CHAMP includes a consolidation mode, where an adjudicator can easily compare multiple cluster hierarchy annotations and resolve disagreements.
CLNov 16, 2023
CARE: Extracting Experimental Findings From Clinical LiteratureAakanksha Naik, Bailey Kuehl, Erin Bransom et al. · allen-ai, cmu
Extracting fine-grained experimental findings from literature can provide dramatic utility for scientific applications. Prior work has developed annotation schemas and datasets for limited aspects of this problem, failing to capture the real-world complexity and nuance required. Focusing on biomedicine, this work presents CARE -- a new IE dataset for the task of extracting clinical findings. We develop a new annotation schema capturing fine-grained findings as n-ary relations between entities and attributes, which unifies phenomena challenging for current IE systems such as discontinuous entity spans, nested relations, variable arity n-ary relations and numeric results in a single schema. We collect extensive annotations for 700 abstracts from two sources: clinical trials and case reports. We also demonstrate the generalizability of our schema to the computer science and materials science domains. We benchmark state-of-the-art IE systems on CARE, showing that even models such as GPT4 struggle. We release our resources to advance research on extracting and aggregating literature findings.
CLJul 6, 2023
Parameter-Efficient Fine-Tuning of LLaMA for the Clinical DomainAryo Pradipta Gema, Pasquale Minervini, Luke Daines et al.
Adapting pretrained language models to novel domains, such as clinical applications, traditionally involves retraining their entire set of parameters. Parameter-Efficient Fine-Tuning (PEFT) techniques for fine-tuning language models significantly reduce computational requirements by selectively fine-tuning small subsets of parameters. In this study, we propose a two-step PEFT framework and evaluate it in the clinical domain. Our approach combines a specialised PEFT adapter layer designed for clinical domain adaptation with another adapter specialised for downstream tasks. We evaluate the framework on multiple clinical outcome prediction datasets, comparing it to clinically trained language models. Our framework achieves a better AUROC score averaged across all clinical downstream tasks compared to clinical language models. In particular, we observe large improvements of 4-5% AUROC in large-scale multilabel classification tasks, such as diagnoses and procedures classification. To our knowledge, this study is the first to provide an extensive empirical analysis of the interplay between PEFT techniques and domain adaptation in an important real-world domain of clinical applications.
92.1CLMay 25
Iterate Until Retrieved: Factual Nugget Optimization for Discoverable Continual Corrections in Agentic RAGMoshe Hazoom, Gal Patel, Alon Talmor et al.
Agentic retrieval-augmented generation (RAG) systems in complex B2B (business-to-business) settings may often receive free-form response feedback. Rather than generic feedback signals such as style, preference, or overall response quality, we focus on actionable factual corrections. We identify these instances and convert them into compact knowledge-base entries, which we call factual nuggets. We introduce Iterative Nugget Optimization (INO), an index-time optimization method that uses the production agentic RAG as a test harness: it creates an initial nugget, probes it with the triggering query and paraphrases, reflects over failed retrieval and answer traces, and revises the nugget until it is discoverable. We evaluate INO with two production B2B knowledge-assistance agents across multiple companies that use our system: a product support agent that answers questions over company-specific knowledge bases, and a support ticket agent that assists support engineers. INO consistently improves results over baselines in terms of discoverability and usage of factual corrections, in automated and human evaluations.
LGMar 23, 2023
Increasing Textual Context Size Boosts Medical Image-Text MatchingIdan Glassberg, Tom Hope
This short technical report demonstrates a simple technique that yields state of the art results in medical image-text matching tasks. We analyze the use of OpenAI's CLIP, a general image-text matching model, and observe that CLIP's limited textual input size has negative impact on downstream performance in the medical domain where encoding longer textual contexts is often required. We thus train and release ClipMD, which is trained with a simple sliding window technique to encode textual captions. ClipMD was tested on two medical image-text datasets and compared with other image-text matching models. The results show that ClipMD outperforms other models on both datasets by a large margin. We make our code and pretrained model publicly available.
AIFeb 24
PreScience: A Benchmark for Forecasting Scientific ContributionsAnirudh Ajith, Amanpreet Singh, Jay DeYoung et al.
Can AI systems trained on the scientific record up to a fixed point in time forecast the scientific advances that follow? Such a capability could help researchers identify collaborators and impactful research directions, and anticipate which problems and methods will become central next. We introduce PreScience -- a scientific forecasting benchmark that decomposes the research process into four interdependent generative tasks: collaborator prediction, prior work selection, contribution generation, and impact prediction. PreScience is a carefully curated dataset of 98K recent AI-related research papers, featuring disambiguated author identities, temporally aligned scholarly metadata, and a structured graph of companion author publication histories and citations spanning 502K total papers. We develop baselines and evaluations for each task, including LACERScore, a novel LLM-based measure of contribution similarity that outperforms previous metrics and approximates inter-annotator agreement. We find substantial headroom remains in each task -- e.g. in contribution generation, frontier LLMs achieve only moderate similarity to the ground-truth (GPT-5, averages 5.6 on a 1-10 scale). When composed into a 12-month end-to-end simulation of scientific production, the resulting synthetic corpus is systematically less diverse and less novel than human-authored research from the same period.
CLMar 29, 2024Code
On-the-fly Definition Augmentation of LLMs for Biomedical NERMonica Munnangi, Sergey Feldman, Byron C Wallace et al. · cmu
Despite their general capabilities, LLMs still struggle on biomedical NER tasks, which are difficult due to the presence of specialized terminology and lack of training data. In this work we set out to improve LLM performance on biomedical NER in limited data settings via a new knowledge augmentation approach which incorporates definitions of relevant concepts on-the-fly. During this process, to provide a test bed for knowledge augmentation, we perform a comprehensive exploration of prompting strategies. Our experiments show that definition augmentation is useful for both open source and closed LLMs. For example, it leads to a relative improvement of 15\% (on average) in GPT-4 performance (F1) across all (six) of our test datasets. We conduct extensive ablations and analyses to demonstrate that our performance improvements stem from adding relevant definitional knowledge. We find that careful prompting strategies also improve LLM performance, allowing them to outperform fine-tuned language models in few-shot settings. To facilitate future research in this direction, we release our code at https://github.com/allenai/beacon.
CVAug 24, 2025Code
Lightweight Joint Optimization of General-Purpose Vision-Language Models and Retrievers for RAG-Based Medical DiagnosisNir Mazor, Tom Hope
Retrieving relevant visual and textual information from medical literature and hospital records can enhance diagnostic accuracy for clinical image interpretation. We develop a multimodal retrieval model jointly optimized with an LVLM for medical diagnosis, unlike standard RAG which doesn't backpropagate LVLM errors to the retriever. Using only general-purpose backbones with lightweight fine-tuning, our model achieves competitive results with medically-pretrained models on clinical classification and VQA tasks. In a novel analysis, we find that different top-retrieved images often yield different predictions for the same target, and that these cases are challenging for all models, even for non-retrieval models. Our joint retrieval optimization significantly improves these cases over standard RAG. However, oracle analysis reveals that while the correct diagnosis is frequently achievable using one of the top retrieved images, in practice there is a large performance gap from the oracle, and rerankers using frontier LVLMs do not close this gap -- leaving ample room for improvement by future methods. Code available at https://github.com/Nirmaz/JOMED.
CLMay 27, 2025Code
CHIMERA: A Knowledge Base of Scientific Idea Recombinations for Research Analysis and IdeationNoy Sternlicht, Tom Hope
A hallmark of human innovation is recombination -- the creation of novel ideas by integrating elements from existing concepts and mechanisms. In this work, we introduce CHIMERA, a large-scale Knowledge Base (KB) of over 28K recombination examples automatically mined from the scientific literature. CHIMERA enables large-scale empirical analysis of how scientists recombine concepts and draw inspiration from different areas, and enables training models that propose novel, cross-disciplinary research directions. To construct this KB, we define a new information extraction task: identifying recombination instances in scientific abstracts. We curate a high-quality, expert-annotated dataset and use it to fine-tune a large language model, which we apply to a broad corpus of AI papers. We showcase the utility of CHIMERA through two applications. First, we analyze patterns of recombination across AI subfields. Second, we train a scientific hypothesis generation model using the KB, showing that it can propose novel research directions that researchers rate as inspiring. We release our data and code at https://github.com/noy-sternlicht/CHIMERA-KB.
CLMay 9, 2023Code
Beyond Good Intentions: Reporting the Research Landscape of NLP for Social GoodFernando Gonzalez, Zhijing Jin, Bernhard Schölkopf et al.
With the recent advances in natural language processing (NLP), a vast number of applications have emerged across various use cases. Among the plethora of NLP applications, many academic researchers are motivated to do work that has a positive social impact, in line with the recent initiatives of NLP for Social Good (NLP4SG). However, it is not always obvious to researchers how their research efforts are tackling today's big social problems. Thus, in this paper, we introduce NLP4SG Papers, a scientific dataset with three associated tasks that can help identify NLP4SG papers and characterize the NLP4SG landscape by: (1) identifying the papers that address a social problem, (2) mapping them to the corresponding UN Sustainable Development Goals (SDGs), and (3) identifying the task they are solving and the methods they are using. Using state-of-the-art NLP models, we address each of these tasks and use them on the entire ACL Anthology, resulting in a visualization workspace that gives researchers a comprehensive overview of the field of NLP4SG. Our website is available at https://nlp4sg.vercel.app. We released our data at https://huggingface.co/datasets/feradauto/NLP4SGPapers and code at https://github.com/feradauto/nlp4sg
CLNov 16, 2021Code
Multi-Vector Models with Textual Guidance for Fine-Grained Scientific Document SimilaritySheshera Mysore, Arman Cohan, Tom Hope
We present a new scientific document similarity model based on matching fine-grained aspects of texts. To train our model, we exploit a naturally-occurring source of supervision: sentences in the full-text of papers that cite multiple papers together (co-citations). Such co-citations not only reflect close paper relatedness, but also provide textual descriptions of how the co-cited papers are related. This novel form of textual supervision is used for learning to match aspects across papers. We develop multi-vector representations where vectors correspond to sentence-level aspects of documents, and present two methods for aspect matching: (1) A fast method that only matches single aspects, and (2) a method that makes sparse multiple matches with an Optimal Transport mechanism that computes an Earth Mover's Distance between aspects. Our approach improves performance on document similarity tasks in four datasets. Further, our fast single-match method achieves competitive results, paving the way for applying fine-grained similarity to large scientific corpora. Code, data, and models available at: https://github.com/allenai/aspire
CLSep 23, 2024
Inferring Scientific Cross-Document Coreference and Hierarchy with Definition-Augmented Relational ReasoningLior Forer, Tom Hope
We address the fundamental task of inferring cross-document coreference and hierarchy in scientific texts, which has important applications in knowledge graph construction, search, recommendation and discovery. Large Language Models (LLMs) can struggle when faced with many long-tail technical concepts with nuanced variations. We present a novel method which generates context-dependent definitions of concept mentions by retrieving full-text literature, and uses the definitions to enhance detection of cross-document relations. We further generate relational definitions, which describe how two concept mentions are related or different, and design an efficient re-ranking approach to address the combinatorial explosion involved in inferring links across papers. In both fine-tuning and in-context learning settings, we achieve large gains in performance on data subsets with high amount of different surfaces forms and ambiguity, that are challenging for models. We provide analysis of generated definitions, shedding light on the relational reasoning ability of LLMs over fine-grained scientific concepts.
CLJan 8, 2024
MARG: Multi-Agent Review Generation for Scientific PapersMike D'Arcy, Tom Hope, Larry Birnbaum et al.
We study the ability of LLMs to generate feedback for scientific papers and develop MARG, a feedback generation approach using multiple LLM instances that engage in internal discussion. By distributing paper text across agents, MARG can consume the full text of papers beyond the input length limitations of the base LLM, and by specializing agents and incorporating sub-tasks tailored to different comment types (experiments, clarity, impact) it improves the helpfulness and specificity of feedback. In a user study, baseline methods using GPT-4 were rated as producing generic or very generic comments more than half the time, and only 1.7 comments per paper were rated as good overall in the best baseline. Our system substantially improves the ability of GPT-4 to generate specific and helpful feedback, reducing the rate of generic comments from 60% to 29% and generating 3.7 good comments per paper (a 2.2x improvement).
CLMay 10, 2024
What Can Natural Language Processing Do for Peer Review?Ilia Kuznetsov, Osama Mohammed Afzal, Koen Dercksen et al.
The number of scientific articles produced every year is growing rapidly. Providing quality control over them is crucial for scientists and, ultimately, for the public good. In modern science, this process is largely delegated to peer review -- a distributed procedure in which each submission is evaluated by several independent experts in the field. Peer review is widely used, yet it is hard, time-consuming, and prone to error. Since the artifacts involved in peer review -- manuscripts, reviews, discussions -- are largely text-based, Natural Language Processing has great potential to improve reviewing. As the emergence of large language models (LLMs) has enabled NLP assistance for many new tasks, the discussion on machine-assisted peer review is picking up the pace. Yet, where exactly is help needed, where can NLP help, and where should it stand aside? The goal of our paper is to provide a foundation for the future efforts in NLP for peer-reviewing assistance. We discuss peer review as a general process, exemplified by reviewing at AI conferences. We detail each step of the process from manuscript submission to camera-ready revision, and discuss the associated challenges and opportunities for NLP assistance, illustrated by existing work. We then turn to the big challenges in NLP for peer review as a whole, including data acquisition and licensing, operationalization and experimentation, and ethical issues. To help consolidate community efforts, we create a companion repository that aggregates key datasets pertaining to peer review. Finally, we issue a detailed call for action for the scientific community, NLP and AI researchers, policymakers, and funding bodies to help bring the research in NLP for peer review forward. We hope that our work will help set the agenda for research in machine-assisted scientific quality control in the age of AI, within the NLP community and beyond.
AIMar 20, 2025
CodeScientist: End-to-End Semi-Automated Scientific Discovery with Code-based ExperimentationPeter Jansen, Oyvind Tafjord, Marissa Radensky et al. · allen-ai
Despite the surge of interest in autonomous scientific discovery (ASD) of software artifacts (e.g., improved ML algorithms), current ASD systems face two key limitations: (1) they largely explore variants of existing codebases or similarly constrained design spaces, and (2) they produce large volumes of research artifacts (such as automatically generated papers and code) that are typically evaluated using conference-style paper review with limited evaluation of code. In this work we introduce CodeScientist, a novel ASD system that frames ideation and experiment construction as a form of genetic search jointly over combinations of research articles and codeblocks defining common actions in a domain (like prompting a language model). We use this paradigm to conduct hundreds of automated experiments on machine-generated ideas broadly in the domain of agents and virtual environments, with the system returning 19 discoveries, 6 of which were judged as being both at least minimally sound and incrementally novel after a multi-faceted evaluation beyond that typically conducted in prior work, including external (conference-style) review, code review, and replication attempts. Moreover, the discoveries span new tasks, agents, metrics, and data, suggesting a qualitative shift from benchmark optimization to broader discoveries.
CLFeb 10
Anagent For Enhancing Scientific Table & Figure AnalysisXuehang Guo, Zhiyong Lu, Tom Hope et al.
In scientific research, analysis requires accurately interpreting complex multimodal knowledge, integrating evidence from different sources, and drawing inferences grounded in domain-specific knowledge. However, current artificial intelligence (AI) systems struggle to consistently demonstrate such capabilities. The complexity and variability of scientific tables and figures, combined with heterogeneous structures and long-context requirements, pose fundamental obstacles to scientific table \& figure analysis. To quantify these challenges, we introduce AnaBench, a large-scale benchmark featuring $63,178$ instances from nine scientific domains, systematically categorized along seven complexity dimensions. To tackle these challenges, we propose Anagent, a multi-agent framework for enhanced scientific table \& figure analysis through four specialized agents: Planner decomposes tasks into actionable subtasks, Expert retrieves task-specific information through targeted tool execution, Solver synthesizes information to generate coherent analysis, and Critic performs iterative refinement through five-dimensional quality assessment. We further develop modular training strategies that leverage supervised finetuning and specialized reinforcement learning to optimize individual capabilities while maintaining effective collaboration. Comprehensive evaluation across 170 subdomains demonstrates that Anagent achieves substantial improvements, up to $\uparrow 13.43\%$ in training-free settings and $\uparrow 42.12\%$ with finetuning, while revealing that task-oriented reasoning and context-aware problem-solving are essential for high-quality scientific table \& figure analysis. Our project page: https://xhguo7.github.io/Anagent/.
IRJun 27, 2025
Literature-Grounded Novelty Assessment of Scientific IdeasSimra Shahid, Marissa Radensky, Raymond Fok et al. · allen-ai, uw
Automated scientific idea generation systems have made remarkable progress, yet the automatic evaluation of idea novelty remains a critical and underexplored challenge. Manual evaluation of novelty through literature review is labor-intensive, prone to error due to subjectivity, and impractical at scale. To address these issues, we propose the Idea Novelty Checker, an LLM-based retrieval-augmented generation (RAG) framework that leverages a two-stage retrieve-then-rerank approach. The Idea Novelty Checker first collects a broad set of relevant papers using keyword and snippet-based retrieval, then refines this collection through embedding-based filtering followed by facet-based LLM re-ranking. It incorporates expert-labeled examples to guide the system in comparing papers for novelty evaluation and in generating literature-grounded reasoning. Our extensive experiments demonstrate that our novelty checker achieves approximately 13% higher agreement than existing approaches. Ablation studies further showcases the importance of the facet-based re-ranker in identifying the most relevant literature for novelty evaluation.
CLFeb 5, 2025
How do Humans and Language Models Reason About Creativity? A Comparative AnalysisAntonio Laverghetta, Tuhin Chakrabarty, Tom Hope et al.
Creativity assessment in science and engineering is increasingly based on both human and AI judgment, but the cognitive processes and biases behind these evaluations remain poorly understood. We conducted two experiments examining how including example solutions with ratings impact creativity evaluation, using a finegrained annotation protocol where raters were tasked with explaining their originality scores and rating for the facets of remoteness (whether the response is "far" from everyday ideas), uncommonness (whether the response is rare), and cleverness. In Study 1, we analyzed creativity ratings from 72 experts with formal science or engineering training, comparing those who received example solutions with ratings (example) to those who did not (no example). Computational text analysis revealed that, compared to experts with examples, no-example experts used more comparative language (e.g., "better/worse") and emphasized solution uncommonness, suggesting they may have relied more on memory retrieval for comparisons. In Study 2, parallel analyses with state-of-the-art LLMs revealed that models prioritized uncommonness and remoteness of ideas when rating originality, suggesting an evaluative process rooted around the semantic similarity of ideas. In the example condition, while LLM accuracy in predicting the true originality scores improved, the correlations of remoteness, uncommonness, and cleverness with originality also increased substantially -- to upwards of $0.99$ -- suggesting a homogenization in the LLMs evaluation of the individual facets. These findings highlight important implications for how humans and AI reason about creativity and suggest diverging preferences for what different populations prioritize when rating.
CLAug 14, 2025
Beyond "Not Novel Enough": Enriching Scholarly Critique with LLM-Assisted FeedbackOsama Mohammed Afzal, Preslav Nakov, Tom Hope et al.
Novelty assessment is a central yet understudied aspect of peer review, particularly in high volume fields like NLP where reviewer capacity is increasingly strained. We present a structured approach for automated novelty evaluation that models expert reviewer behavior through three stages: content extraction from submissions, retrieval and synthesis of related work, and structured comparison for evidence based assessment. Our method is informed by a large scale analysis of human written novelty reviews and captures key patterns such as independent claim verification and contextual reasoning. Evaluated on 182 ICLR 2025 submissions with human annotated reviewer novelty assessments, the approach achieves 86.5% alignment with human reasoning and 75.3% agreement on novelty conclusions - substantially outperforming existing LLM based baselines. The method produces detailed, literature aware analyses and improves consistency over ad hoc reviewer judgments. These results highlight the potential for structured LLM assisted approaches to support more rigorous and transparent peer review without displacing human expertise. Data and code are made available.
DLMay 20, 2025
In-depth Research Impact Summarization through Fine-Grained Temporal Citation AnalysisHiba Arnaout, Noy Sternlicht, Tom Hope et al.
Understanding the impact of scientific publications is crucial for identifying breakthroughs and guiding future research. Traditional metrics based on citation counts often miss the nuanced ways a paper contributes to its field. In this work, we propose a new task: generating nuanced, expressive, and time-aware impact summaries that capture both praise (confirmation citations) and critique (correction citations) through the evolution of fine-grained citation intents. We introduce an evaluation framework tailored to this task, showing moderate to strong human correlation on subjective metrics such as insightfulness. Expert feedback from professors reveals a strong interest in these summaries and suggests future improvements.
CLSep 1, 2025
ABCD-LINK: Annotation Bootstrapping for Cross-Document Fine-Grained LinksSerwar Basch, Ilia Kuznetsov, Tom Hope et al.
Understanding fine-grained relations between documents is crucial for many application domains. However, the study of automated assistance is limited by the lack of efficient methods to create training and evaluation datasets of cross-document links. To address this, we introduce a new domain-agnostic framework for selecting a best-performing approach and annotating cross-document links in a new domain from scratch. We first generate and validate semi-synthetic datasets of interconnected documents. This data is used to perform automatic evaluation, producing a shortlist of best-performing linking approaches. These approaches are then used in an extensive human evaluation study, yielding performance estimates on natural text pairs. We apply our framework in two distinct domains -- peer review and news -- and show that combining retrieval models with LLMs achieves 78\% link approval from human raters, more than doubling the precision of strong retrievers alone. Our framework enables systematic study of cross-document understanding across application scenarios, and the resulting novel datasets lay foundation for numerous cross-document tasks like media framing and peer review. We make the code, data, and annotation protocols openly available.
CLJun 5, 2025
Debatable Intelligence: Benchmarking LLM Judges via Debate Speech EvaluationNoy Sternlicht, Ariel Gera, Roy Bar-Haim et al.
We introduce Debate Speech Evaluation as a novel and challenging benchmark for assessing LLM judges. Evaluating debate speeches requires a deep understanding of the speech at multiple levels, including argument strength and relevance, the coherence and organization of the speech, the appropriateness of its style and tone, and so on. This task involves a unique set of cognitive abilities that previously received limited attention in systematic LLM benchmarking. To explore such skills, we leverage a dataset of over 600 meticulously annotated debate speeches and present the first in-depth analysis of how state-of-the-art LLMs compare to human judges on this task. Our findings reveal a nuanced picture: while larger models can approximate individual human judgments in some respects, they differ substantially in their overall judgment behavior. We also investigate the ability of frontier LLMs to generate persuasive, opinionated speeches, showing that models may perform at a human level on this task.
CLJun 10, 2024
SciRIFF: A Resource to Enhance Language Model Instruction-Following over Scientific LiteratureDavid Wadden, Kejian Shi, Jacob Morrison et al.
We present SciRIFF (Scientific Resource for Instruction-Following and Finetuning), a dataset of 137K instruction-following instances for training and evaluation, covering 54 tasks. These tasks span five core scientific literature understanding capabilities: information extraction, summarization, question answering, claim verification, and classification. SciRIFF is unique in being entirely expert-written, high-quality instruction-following dataset for extracting and synthesizing information from research literature across diverse scientific fields. It features complex instructions with long input contexts, detailed task descriptions, and structured outputs. To demonstrate its utility, we finetune a series of large language models (LLMs) using a mix of general-domain and SciRIFF instructions. On nine out-of-distribution held-out tasks (referred to as SciRIFF-Eval), LLMs finetuned on SciRIFF achieve 70.6% average improvement over baselines trained only on general-domain instructions. SciRIFF facilitates the development and evaluation of LLMs to help researchers navigate the rapidly growing body of scientific literature.
CLMay 23, 2023
SciMON: Scientific Inspiration Machines Optimized for NoveltyQingyun Wang, Doug Downey, Heng Ji et al.
We explore and enhance the ability of neural language models to generate novel scientific directions grounded in literature. Work on literature-based hypothesis generation has traditionally focused on binary link prediction--severely limiting the expressivity of hypotheses. This line of work also does not focus on optimizing novelty. We take a dramatic departure with a novel setting in which models use as input background contexts (e.g., problems, experimental settings, goals), and output natural language ideas grounded in literature. We present SciMON, a modeling framework that uses retrieval of "inspirations" from past scientific papers, and explicitly optimizes for novelty by iteratively comparing to prior papers and updating idea suggestions until sufficient novelty is achieved. Comprehensive evaluations reveal that GPT-4 tends to generate ideas with overall low technical depth and novelty, while our methods partially mitigate this issue. Our work represents a first step toward evaluating and developing language models that generate new ideas derived from the scientific literature
CLNov 16, 2021
Literature-Augmented Clinical Outcome PredictionAakanksha Naik, Sravanthi Parasa, Sergey Feldman et al.
We present BEEP (Biomedical Evidence-Enhanced Predictions), a novel approach for clinical outcome prediction that retrieves patient-specific medical literature and incorporates it into predictive models. Based on each individual patient's clinical notes, we train language models (LMs) to find relevant papers and fuse them with information from notes to predict outcomes such as in-hospital mortality. We develop methods to retrieve literature based on noisy, information-dense patient notes, and to augment existing outcome prediction models with retrieved papers in a manner that maximizes predictive accuracy. Our approach boosts predictive performance on three important clinical tasks in comparison to strong recent LM baselines, increasing F1 by up to 5 points and precision@Top-K by a large margin of over 25%.
CLAug 31, 2021
A Search Engine for Discovery of Scientific Challenges and DirectionsDan Lahav, Jon Saad Falcon, Bailey Kuehl et al.
Keeping track of scientific challenges, advances and emerging directions is a fundamental part of research. However, researchers face a flood of papers that hinders discovery of important knowledge. In biomedicine, this directly impacts human lives. To address this problem, we present a novel task of extraction and search of scientific challenges and directions, to facilitate rapid knowledge discovery. We construct and release an expert-annotated corpus of texts sampled from full-length papers, labeled with novel semantic categories that generalize across many types of challenges and directions. We focus on a large corpus of interdisciplinary work relating to the COVID-19 pandemic, ranging from biomedicine to areas such as AI and economics. We apply a model trained on our data to identify challenges and directions across the corpus and build a dedicated search engine. In experiments with 19 researchers and clinicians using our system, we outperform a popular scientific search engine in assisting knowledge discovery. Finally, we show that models trained on our resource generalize to the wider biomedical domain and to AI papers, highlighting its broad utility. We make our data, model and search engine publicly available. https://challenges.apps.allenai.org/
DLAug 12, 2021
Bursting Scientific Filter Bubbles: Boosting Innovation via Novel Author DiscoveryJason Portenoy, Marissa Radensky, Jevin West et al.
Isolated silos of scientific research and the growing challenge of information overload limit awareness across the literature and hinder innovation. Algorithmic curation and recommendation, which often prioritize relevance, can further reinforce these informational "filter bubbles." In response, we describe Bridger, a system for facilitating discovery of scholars and their work. We construct a faceted representation of authors with information gleaned from their papers and inferred author personas, and use it to develop an approach that locates commonalities and contrasts between scientists to balance relevance and novelty. In studies with computer science researchers, this approach helps users discover authors considered useful for generating novel research directions. We also demonstrate an approach for displaying information about authors, boosting the ability to understand the work of new, unfamiliar scholars. Our analysis reveals that Bridger connects authors who have different citation profiles and publish in different venues, raising the prospect of bridging diverse scientific communities.
CLJun 17, 2021
Scientific Language Models for Biomedical Knowledge Base Completion: An Empirical StudyRahul Nadkarni, David Wadden, Iz Beltagy et al.
Biomedical knowledge graphs (KGs) hold rich information on entities such as diseases, drugs, and genes. Predicting missing links in these graphs can boost many important applications, such as drug design and repurposing. Recent work has shown that general-domain language models (LMs) can serve as "soft" KGs, and that they can be fine-tuned for the task of KG completion. In this work, we study scientific LMs for KG completion, exploring whether we can tap into their latent knowledge to enhance biomedical link prediction. We evaluate several domain-specific LMs, fine-tuning them on datasets centered on drugs and diseases that we represent as KGs and enrich with textual entity descriptions. We integrate the LM-based models with KG embedding models, using a router method that learns to assign each input example to either type of model and provides a substantial boost in performance. Finally, we demonstrate the advantage of LM models in the inductive setting with novel scientific entities. Our datasets and code are made publicly available.
CLApr 18, 2021
SciCo: Hierarchical Cross-Document Coreference for Scientific ConceptsArie Cattan, Sophie Johnson, Daniel Weld et al.
Determining coreference of concept mentions across multiple documents is a fundamental task in natural language understanding. Previous work on cross-document coreference resolution (CDCR) typically considers mentions of events in the news, which seldom involve abstract technical concepts that are prevalent in science and technology. These complex concepts take diverse or ambiguous forms and have many hierarchical levels of granularity (e.g., tasks and subtasks), posing challenges for CDCR. We present a new task of Hierarchical CDCR (H-CDCR) with the goal of jointly inferring coreference clusters and hierarchy between them. We create SciCo, an expert-annotated dataset for H-CDCR in scientific papers, 3X larger than the prominent ECB+ resource. We study strong baseline models that we customize for H-CDCR, and highlight challenges for future work.
HCFeb 19, 2021
Scaling Creative Inspiration with Fine-Grained Functional Aspects of IdeasTom Hope, Ronen Tamari, Hyeonsu Kang et al.
Large repositories of products, patents and scientific papers offer an opportunity for building systems that scour millions of ideas and help users discover inspirations. However, idea descriptions are typically in the form of unstructured text, lacking key structure that is required for supporting creative innovation interactions. Prior work has explored idea representations that were either limited in expressivity, required significant manual effort from users, or dependent on curated knowledge bases with poor coverage. We explore a novel representation that automatically breaks up products into fine-grained functional aspects capturing the purposes and mechanisms of ideas, and use it to support important creative innovation interactions: functional search for ideas, and exploration of the design space around a focal problem by viewing related problem perspectives pooled from across many products. In user studies, our approach boosts the quality of creative search and inspirations, substantially outperforming strong baselines by 50-60%.
CLOct 8, 2020
Extracting a Knowledge Base of Mechanisms from COVID-19 PapersTom Hope, Aida Amini, David Wadden et al.
The COVID-19 pandemic has spawned a diverse body of scientific literature that is challenging to navigate, stimulating interest in automated tools to help find useful knowledge. We pursue the construction of a knowledge base (KB) of mechanisms -- a fundamental concept across the sciences encompassing activities, functions and causal relations, ranging from cellular processes to economic impacts. We extract this information from the natural language of scientific papers by developing a broad, unified schema that strikes a balance between relevance and breadth. We annotate a dataset of mechanisms with our schema and train a model to extract mechanism relations from papers. Our experiments demonstrate the utility of our KB in supporting interdisciplinary scientific search over COVID-19 literature, outperforming the prominent PubMed search in a study with clinical experts.
IRMay 20, 2020
SciSight: Combining faceted navigation and research group detection for COVID-19 exploratory scientific searchTom Hope, Jason Portenoy, Kishore Vasan et al.
The COVID-19 pandemic has sparked unprecedented mobilization of scientists, generating a deluge of papers that makes it hard for researchers to keep track and explore new directions. Search engines are designed for targeted queries, not for discovery of connections across a corpus. In this paper, we present SciSight, a system for exploratory search of COVID-19 research integrating two key capabilities: first, exploring associations between biomedical facets automatically extracted from papers (e.g., genes, drugs, diseases, patient outcomes); second, combining textual and network information to search and visualize groups of researchers and their ties. SciSight has so far served over $15K$ users with over $42K$ page views and $13\%$ returns.
CLMay 1, 2020
Language (Re)modelling: Towards Embodied Language UnderstandingRonen Tamari, Chen Shani, Tom Hope et al.
While natural language understanding (NLU) is advancing rapidly, today's technology differs from human-like language understanding in fundamental ways, notably in its inferior efficiency, interpretability, and generalization. This work proposes an approach to representation and learning based on the tenets of embodied cognitive linguistics (ECL). According to ECL, natural language is inherently executable (like programming languages), driven by mental simulation and metaphoric mappings over hierarchical compositions of structures and schemata learned through embodied interaction. This position paper argues that the use of grounding by metaphoric inference and simulation will greatly benefit NLU systems, and proposes a system architecture along with a roadmap towards realizing this vision.
LGDec 9, 2019
A Weak Supervision Approach to Detecting Visual Anomalies for Automated Testing of Graphics UnitsAdi Szeskin, Lev Faivishevsky, Ashwin K Muppalla et al.
We present a deep learning system for testing graphics units by detecting novel visual corruptions in videos. Unlike previous work in which manual tagging was required to collect labeled training data, our weak supervision method is fully automatic and needs no human labelling. This is achieved by reproducing driver bugs that increase the probability of generating corruptions, and by making use of ideas and methods from the Multiple Instance Learning (MIL) setting. In our experiments, we significantly outperform unsupervised methods such as GAN-based models and discover novel corruptions undetected by baselines, while adhering to strict requirements on accuracy and efficiency of our real-time system.
IRNov 27, 2019
Learning a faceted customer segmentation for discovering new business opportunities at IntelItay Lieder, Meirav Segal, Eran Avidan et al.
For sales and marketing organizations within large enterprises, identifying and understanding new markets, customers and partners is a key challenge. Intel's Sales and Marketing Group (SMG) faces similar challenges while growing in new markets and domains and evolving its existing business. In today's complex technological and commercial landscape, there is need for intelligent automation supporting a fine-grained understanding of businesses in order to help SMG sift through millions of companies across many geographies and languages and identify relevant directions. We present a system developed in our company that mines millions of public business web pages, and extracts a faceted customer representation. We focus on two key customer aspects that are essential for finding relevant opportunities: industry segments (ranging from broad verticals such as healthcare, to more specific fields such as 'video analytics') and functional roles (e.g., 'manufacturer' or 'retail'). To address the challenge of labeled data collection, we enrich our data with external information gleaned from Wikipedia, and develop a semi-supervised multi-label, multi-lingual deep learning model that parses customer website texts and classifies them into their respective facets. Our system scans and indexes companies as part of a large-scale knowledge graph that currently holds tens of millions of connected entities with thousands being fetched, enriched and connected to the graph by the hour in real time, and also supports knowledge and insight discovery. In experiments conducted in our company, we are able to significantly boost the performance of sales personnel in the task of discovering new customers and commercial partnership opportunities.
MLDec 13, 2017
Ballpark Crowdsourcing: The Wisdom of Rough Group ComparisonsTom Hope, Dafna Shahaf
Crowdsourcing has become a popular method for collecting labeled training data. However, in many practical scenarios traditional labeling can be difficult for crowdworkers (for example, if the data is high-dimensional or unintuitive, or the labels are continuous). In this work, we develop a novel model for crowdsourcing that can complement standard practices by exploiting people's intuitions about groups and relations between them. We employ a recent machine learning setting, called Ballpark Learning, that can estimate individual labels given only coarse, aggregated signal over groups of data points. To address the important case of continuous labels, we extend the Ballpark setting (which focused on classification) to regression problems. We formulate the problem as a convex optimization problem and propose fast, simple methods with an innate robustness to outliers. We evaluate our methods on real-world datasets, demonstrating how useful constraints about groups can be harnessed from a crowd of non-experts. Our methods can rival supervised models trained on many true labels, and can obtain considerably better results from the crowd than a standard label-collection process (for a lower price). By collecting rough guesses on groups of instances and using machine learning to infer the individual labels, our lightweight framework is able to address core crowdsourcing challenges and train machine learning models in a cost-effective way.
CLJun 17, 2017
Accelerating Innovation Through Analogy MiningTom Hope, Joel Chan, Aniket Kittur et al.
The availability of large idea repositories (e.g., the U.S. patent database) could significantly accelerate innovation and discovery by providing people with inspiration from solutions to analogous problems. However, finding useful analogies in these large, messy, real-world repositories remains a persistent challenge for either human or automated methods. Previous approaches include costly hand-created databases that have high relational structure (e.g., predicate calculus representations) but are very sparse. Simpler machine-learning/information-retrieval similarity metrics can scale to large, natural-language datasets, but struggle to account for structural similarity, which is central to analogy. In this paper we explore the viability and value of learning simpler structural representations, specifically, "problem schemas", which specify the purpose of a product and the mechanisms by which it achieves that purpose. Our approach combines crowdsourcing and recurrent neural networks to extract purpose and mechanism vector representations from product descriptions. We demonstrate that these learned vectors allow us to find analogies with higher precision and recall than traditional information-retrieval methods. In an ideation experiment, analogies retrieved by our models significantly increased people's likelihood of generating creative ideas compared to analogies retrieved by traditional methods. Our results suggest a promising approach to enabling computational analogy at scale is to learn and leverage weaker structural representations.
MLJun 30, 2016
Ballpark Learning: Estimating Labels from Rough Group ComparisonsTom Hope, Dafna Shahaf
We are interested in estimating individual labels given only coarse, aggregated signal over the data points. In our setting, we receive sets ("bags") of unlabeled instances with constraints on label proportions. We relax the unrealistic assumption of known label proportions, made in previous work; instead, we assume only to have upper and lower bounds, and constraints on bag differences. We motivate the problem, propose an intuitive formulation and algorithm, and apply our methods to real-world scenarios. Across several domains, we show how using only proportion constraints and no labeled examples, we can achieve surprisingly high accuracy. In particular, we demonstrate how to predict income level using rough stereotypes and how to perform sentiment analysis using very little information. We also apply our method to guide exploratory analysis, recovering geographical differences in twitter dialect.
LGOct 18, 2015
Clustering Noisy Signals with Structured Sparsity Using Time-Frequency RepresentationTom Hope, Avishai Wagner, Or Zuk
We propose a simple and efficient time-series clustering framework particularly suited for low Signal-to-Noise Ratio (SNR), by simultaneous smoothing and dimensionality reduction aimed at preserving clustering information. We extend the sparse K-means algorithm by incorporating structured sparsity, and use it to exploit the multi-scale property of wavelets and group structure in multivariate signals. Finally, we extract features invariant to translation and scaling with the scattering transform, which corresponds to a convolutional network with filters given by a wavelet operator, and use the network's structure in sparse clustering. By promoting sparsity, this transform can yield a low-dimensional representation of signals that gives improved clustering results on several real datasets.