Ruihao Zhang

Yuxin He, Ruihao Zhang, Tianao Shen et al.

Recently, active vision has reemerged as an important concept for manipulation, since visual occlusion occurs more frequently when main cameras are mounted on the robot heads. We reflect on the visual occlusion issue and identify its essence as the absence of information useful for task completion. Inspired by this, we come up with the more fundamental problem of Exploratory and Focused Manipulation (EFM). The proposed problem is about actively collecting information to complete challenging manipulation tasks that require exploration or focus. As an initial attempt to address this problem, we establish the EFM-10 benchmark that consists of 4 categories of tasks that align with our definition (10 tasks in total). We further come up with a Bimanual Active Perception (BAP) strategy, which leverages one arm to provide active vision and another arm to provide force sensing while manipulating. Based on this idea, we collect a dataset named BAPData for the tasks in EFM-10. With the dataset, we successfully verify the effectiveness of the BAP strategy in an imitation learning manner. We hope that the EFM-10 benchmark along with the BAP strategy can become a cornerstone that facilitates future research towards this direction. Project website: EFManipulation.github.io.

Jinluan Yang, Ruihao Zhang, Zhengyu Chen et al.

This paper studies the problem of distribution shifts on non-homophilous graphs Mosting existing graph neural network methods rely on the homophilous assumption that nodes from the same class are more likely to be linked. However, such assumptions of homophily do not always hold in real-world graphs, which leads to more complex distribution shifts unaccounted for in previous methods. The distribution shifts of neighborhood patterns are much more diverse on non-homophilous graphs. We propose a novel Invariant Neighborhood Pattern Learning (INPL) to alleviate the distribution shifts problem on non-homophilous graphs. Specifically, we propose the Adaptive Neighborhood Propagation (ANP) module to capture the adaptive neighborhood information, which could alleviate the neighborhood pattern distribution shifts problem on non-homophilous graphs. We propose Invariant Non-Homophilous Graph Learning (INHGL) module to constrain the ANP and learn invariant graph representation on non-homophilous graphs. Extensive experimental results on real-world non-homophilous graphs show that INPL could achieve state-of-the-art performance for learning on large non-homophilous graphs.

Jinluan Yang, Ruihao Zhang, Zhengyu Chen et al.

This paper studies the vulnerability of Graph Neural Networks (GNNs) to adversarial attacks on node features and graph structure. Various methods have implemented adversarial training to augment graph data, aiming to bolster the robustness and generalization of GNNs. These methods typically involve applying perturbations to the node feature, weights, or graph structure and subsequently minimizing the loss by learning more robust graph model parameters under the adversarial perturbations. Despite the effectiveness of adversarial training in enhancing GNNs' robustness and generalization abilities, its application has been largely confined to specific datasets and GNN types. In this paper, we propose a novel method, PerturbEmbedding, that integrates adversarial perturbation and training, enhancing GNNs' resilience to such attacks and improving their generalization ability. PerturbEmbedding performs perturbation operations directly on every hidden embedding of GNNs and provides a unified framework for most existing perturbation strategies/methods. We also offer a unified perspective on the forms of perturbations, namely random and adversarial perturbations. Through experiments on various datasets using different backbone models, we demonstrate that PerturbEmbedding significantly improves both the robustness and generalization abilities of GNNs, outperforming existing methods. The rejection of both random (non-targeted) and adversarial (targeted) perturbations further enhances the backbone model's performance.

Ruihao Zhang, Mao chen, Fei Ye et al.

T cell receptor (TCR) repertoires encode critical immunological signatures for autoimmune diseases, yet their clinical application remains limited by sequence sparsity and low witness rates. We developed EAMil, a multi-instance deep learning framework that leverages TCR sequencing data to diagnose systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA) with exceptional accuracy. By integrating PrimeSeq feature extraction with ESMonehot encoding and enhanced gate attention mechanisms, our model achieved state-of-the-art performance with AUCs of 98.95% for SLE and 97.76% for RA. EAMil successfully identified disease-associated genes with over 90% concordance with established differential analyses and effectively distinguished disease-specific TCR genes. The model demonstrated robustness in classifying multiple disease categories, utilizing the SLEDAI score to stratify SLE patients by disease severity as well as to diagnose the site of damage in SLE patients, and effectively controlling for confounding factors such as age and gender. This interpretable framework for immune receptor analysis provides new insights for autoimmune disease detection and classification with broad potential clinical applications across immune-mediated conditions.