Zhigang Wu

Beier Hu, Yuanshen Guo, Jialu Cai et al.

Cross-view geo-localization (CVGL) is critical for Unmanned Aerial Vehicle (UAV) self-positioning and target localization in GNSS-denied environments. However, acquiring robust semantics while preserving finegrained spatial details remains challenging. To address this, we propose DINO-GFSA, a framework leveraging a LoRA (Low-Rank Adaptation) adapted DINOv3 (ViTL) backbone for parameter-efficient, high-capacity representation. Crucially, we introduce a Semantic Gated Residual Fusion module, which utilizes high-level semantics to selectively calibrate and integrate low-level spatial cues, effectively bridging the semantic gap. Furthermore, a Mamba-based Sequential Aggregation Head is designed to capture long-range spatial dependencies with linear complexity. Experiments demonstrate state-of-the-art performance on University-1652 and DenseUAV benchmarks, notably surpassing the previous best on DenseUAV by 3.48% on Recall@1. These results validate DINO-GFSA as a generalized, robust solution for UAV CVGL.

Dicheng Chen, Meijin Lin, Huiting Liu et al.

Objective: Magnetic Resonance Spectroscopy (MRS) is an important technique for biomedical detection. However, it is challenging to accurately quantify metabolites with proton MRS due to serious overlaps of metabolite signals, imperfections because of non-ideal acquisition conditions, and interference with strong background signals mainly from macromolecules. The most popular method, LCModel, adopts complicated non-linear least square to quantify metabolites and addresses these problems by designing empirical priors such as basis-sets, imperfection factors. However, when the signal-to-noise ratio of MRS signal is low, the solution may have large deviation. Methods: Linear Least Squares (LLS) is integrated with deep learning to reduce the complexity of solving this overall quantification. First, a neural network is designed to explicitly predict the imperfection factors and the overall signal from macromolecules. Then, metabolite quantification is solved analytically with the introduced LLS. In our Quantification Network (QNet), LLS takes part in the backpropagation of network training, which allows the feedback of the quantification error into metabolite spectrum estimation. This scheme greatly improves the generalization to metabolite concentrations unseen for training compared to the end-to-end deep learning method. Results: Experiments show that compared with LCModel, the proposed QNet, has smaller quantification errors for simulated data, and presents more stable quantification for 20 healthy in vivo data at a wide range of signal-to-noise ratio. QNet also outperforms other end-to-end deep learning methods. Conclusion: This study provides an intelligent, reliable and robust MRS quantification. Significance: QNet is the first LLS quantification aided by deep learning.

Chen Qian, Haoyu Zhang, Yuncheng Gao et al.

Diffusion magnetic resonance imaging (MRI) is the only imaging modality for non-invasive movement detection of in vivo water molecules, with significant clinical and research applications. Diffusion weighted imaging (DWI) MRI acquired by multi-shot techniques can achieve higher resolution, better signal-to-noise ratio, and lower geometric distortion than single-shot, but suffers from inter-shot motion-induced artifacts. These artifacts cannot be removed prospectively, leading to the absence of artifact-free training labels. Thus, the potential of deep learning in multi-shot DWI reconstruction remains largely untapped. To break the training data bottleneck, here, we propose a Physics-Informed Deep DWI reconstruction method (PIDD) to synthesize high-quality paired training data by leveraging the physical diffusion model (magnitude synthesis) and inter-shot motion-induced phase model (motion phase synthesis). The network is trained only once with 100,000 synthetic samples, achieving encouraging results on multiple realistic in vivo data reconstructions. Advantages over conventional methods include: (a) Better motion artifact suppression and reconstruction stability; (b) Outstanding generalization to multi-scenario reconstructions, including multi-resolution, multi-b-value, multi-under-sampling, multi-vendor, and multi-center; (c) Excellent clinical adaptability to patients with verifications by seven experienced doctors (p<0.001). In conclusion, PIDD presents a novel deep learning framework by exploiting the power of MRI physics, providing a cost-effective and explainable way to break the data bottleneck in deep learning medical imaging.

Bohan Zhang, Bo Wang, Huajiang Ouyang et al.

Origami inspired architectures offer a powerful route toward lightweight, reconfigurable, and programmable robotic systems. Yet, a unified mechanics framework capable of seamlessly bridging rigid folding, elastic deformation, and stability driven transitions in compliant origami remains lacking. Here, we introduce a geometry consistent modeling framework based on discrete differential geometry (DDG) that unifies panel elasticity and crease rotation within a single variational formulation. By embedding crease panel coupling directly into a mid edge geometric discretization, the framework naturally captures rigid folding limits, distributed bending, multistability, and nonlinear dynamic snap through within one mechanically consistent structure. This unified description enables programmable control of stability and deformation across rigid and compliant regimes, allowing origami structures to transition from static folding mechanisms to active robotic modules. An implicit dynamic formulation incorporating gravity, contact, friction, and magnetic actuation further supports strongly coupled multiphysics simulations. Through representative examples spanning single fold bifurcation, deployable Miura membranes, bistable Waterbomb modules, and Kresling based crawling robots, we demonstrate how geometry driven mechanics directly informs robotic functionality. This work establishes discrete differential geometry as a foundational design language for intelligent origami robotics, enabling predictive modeling, stability programming, and mechanics guided robotic actuation within a unified computational platform.

Yichi Zhang, Le Xue, Bichun Xu et al.

Semi-supervised learning (SSL) has become a promising solution to alleviate the annotation burden of deep learning-based medical image segmentation models. While recent advances in foundation model-driven SSL have pushed the boundary to extremely limited annotation scenarios, they fail to maintain robust competitive performance in complex imaging modalities. In this paper, we propose SemiSAM-O1, an annotation-efficient framework using only one annotated template image for segmentation. SemiSAM-O1 extends the specialist-generalist collaborative learning framework to the extreme one-label setting by fully exploiting the foundation model's feature representation capability beyond its prompting interface. SemiSAM-O1 operates in two stages. In the first stage, the foundation model's encoder extracts dense features from all volumes, and class prototypes derived from the single annotated template are propagated to the unlabeled pool via feature similarity to produce coarse initial pseudo-labels. In the second stage, an iterative training-and-refinement loop progressively improves both the segmentation model and the pseudo-labels over multiple rounds, where each round trains the model from scratch on current pseudo-labels and generates updated predictions with voxel-wise uncertainty estimates. An uncertainty-guided refinement step further leverages the foundation model's global feature space to correct high-uncertainty regions by aggregating labels from their most similar confident neighbors, establishing a virtuous cycle of mutual improvement. Extensive experiments on a wide range of segmentation tasks across different modalities and anatomical targets demonstrate that SemiSAM-O1 significantly narrows the performance gap between one-label semi-supervised learning and full supervision, while significantly reducing the computational overhead of online foundation model inference.

Yiyang Chen, Zhigang Wu, Guohong Zheng et al.

The trajectory data of traffic participants (TPs) is a fundamental resource for evaluating traffic conditions and optimizing policies, especially at urban intersections. Although data acquisition using drones is efficient, existing datasets still have limitations in scene representativeness, information richness, and data fidelity. This study introduces FLUID, comprising a fine-grained trajectory dataset that captures dense conflicts at typical urban signalized intersections, and a lightweight, full-pipeline framework for drone-based trajectory processing. FLUID covers three distinct intersection types, with approximately 5 hours of recording time and featuring over 20,000 TPs across 8 categories. Notably, the dataset averages two vehicle conflicts per minute, involving roughly 25% of all motor vehicles. FLUID provides comprehensive data, including trajectories, traffic signals, maps, and raw videos. Comparison with the DataFromSky platform and ground-truth measurements validates its high spatio-temporal accuracy. Through a detailed classification of motor vehicle conflicts and violations, FLUID reveals a diversity of interactive behaviors, demonstrating its value for human preference mining, traffic behavior modeling, and autonomous driving research.

Dicheng Chen, Wanqi Hu, Huiting Liu et al.

Magnetic Resonance Spectroscopy (MRS) is a noninvasive tool to reveal metabolic information. One challenge of 1H-MRS is the low Signal-Noise Ratio (SNR). To improve the SNR, a typical approach is to perform Signal Averaging (SA) with M repeated samples. The data acquisition time, however, is increased by M times accordingly, and a complete clinical MRS scan takes approximately 10 minutes at a common setting M=128. Recently, deep learning has been introduced to improve the SNR but most of them use the simulated data as the training set. This may hinder the MRS applications since some potential differences, such as acquisition system imperfections, and physiological and psychologic conditions may exist between the simulated and in vivo data. Here, we proposed a new scheme that purely used the repeated samples of realistic data. A deep learning model, Refusion Long Short-Term Memory (ReLSTM), was designed to learn the mapping from the low SNR time-domain data (24 SA) to the high SNR one (128 SA). Experiments on the in vivo brain spectra of 7 healthy subjects, 2 brain tumor patients and 1 cerebral infarction patient showed that only using 20% repeated samples, the denoised spectra by ReLSTM could provide comparable estimated concentrations of metabolites to 128 SA. Compared with the state-of-the-art low-rank denoising method, the ReLSTM achieved the lower relative error and the Cramér-Rao lower bounds in quantifying some important biomarkers. In summary, ReLSTM can perform high-fidelity denoising of the spectra under fast acquisition (24 SA), which would be valuable to MRS clinical studies.