59.6LGJun 3
Federated Learning for Multi-Center Sepsis Early Prediction with Privacy-PreservingXixi Tian, Di Wu, Xiang Liu et al.
Privacy-sensitive and distributed characteristics of multi-center medical data bring severe obstacles to centralized modeling for accurate early prediction of sepsis. Federated learning (FL) has attracted growing attention as a promising framework for collaborative model development, as it allows multiple institutions to jointly train predictive models without directly sharing or centralizing raw data. Nevertheless, its practical performance, robustness, and privacy-preserving benefits remain insufficiently evaluated using real-world clinical datasets. To bridge this gap, this study systematically examines the application of federated learning to multi-center sepsis prediction. The experimental dataset consists of 648 clinically screened samples collected from three tertiary hospitals in China, with rigorous inclusion and exclusion criteria. We establish a centralized training paradigm as the performance baseline, and then implement a horizontal federated learning framework for distributed collaborative modeling. Extensive experimental results demonstrate that the federated learning-based model achieves highly comparable prediction accuracy to the centralized counterpart, while fundamentally avoiding privacy leakage. Further privacy security analysis verifies that malicious attackers cannot reconstruct the original patient data from the transmitted model parameters, indicating strong resistance against data reconstruction attacks. This work not only validates the practicality and security of federated learning in clinical sepsis prediction, but also provides a reliable and feasible solution for privacy-preserving multi-center medical collaboration.
OPTICSJul 22, 2023
High-performance real-world optical computing trained by in situ gradient-based model-free optimizationGuangyuan Zhao, Xin Shu, Renjie Zhou
Optical computing systems provide high-speed and low-energy data processing but face deficiencies in computationally demanding training and simulation-to-reality gaps. We propose a gradient-based model-free optimization (G-MFO) method based on a Monte Carlo gradient estimation algorithm for computationally efficient in situ training of optical computing systems. This approach treats an optical computing system as a black box and back-propagates the loss directly to the optical computing weights' probability distributions, circumventing the need for a computationally heavy and biased system simulation. Our experiments on diffractive optical computing systems show that G-MFO outperforms hybrid training on the MNIST and FMNIST datasets. Furthermore, we demonstrate image-free and high-speed classification of cells from their marker-free phase maps. Our method's model-free and high-performance nature, combined with its low demand for computational resources, paves the way for accelerating the transition of optical computing from laboratory demonstrations to practical, real-world applications.
CVAug 30, 2023
Occlusion-Aware Detection and Re-ID Calibrated Network for Multi-Object TrackingYukun Su, Ruizhou Sun, Xin Shu et al.
Multi-Object Tracking (MOT) is a crucial computer vision task that aims to predict the bounding boxes and identities of objects simultaneously. While state-of-the-art methods have made remarkable progress by jointly optimizing the multi-task problems of detection and Re-ID feature learning, yet, few approaches explore to tackle the occlusion issue, which is a long-standing challenge in the MOT field. Generally, occluded objects may hinder the detector from estimating the bounding boxes, resulting in fragmented trajectories. And the learned occluded Re-ID embeddings are less distinct since they contain interferer. To this end, we propose an occlusion-aware detection and Re-ID calibrated network for multi-object tracking, termed as ORCTrack. Specifically, we propose an Occlusion-Aware Attention (OAA) module in the detector that highlights the object features while suppressing the occluded background regions. OAA can serve as a modulator that enhances the detector for some potentially occluded objects. Furthermore, we design a Re-ID embedding matching block based on the optimal transport problem, which focuses on enhancing and calibrating the Re-ID representations through different adjacent frames complementarily. To validate the effectiveness of the proposed method, extensive experiments are conducted on two challenging VisDrone2021-MOT and KITTI benchmarks. Experimental evaluations demonstrate the superiority of our approach, which can achieve new state-of-the-art performance and enjoy high run-time efficiency.
IVOct 25, 2022
Neural Architecture Search generated Phase Retrieval Net for Real-time Off-axis Quantitative Phase ImagingXin Shu, Mengxuan Niu, Yi Zhang et al.
In off-axis Quantitative Phase Imaging (QPI), artificial neural networks have been recently applied for phase retrieval with aberration compensation and phase unwrapping. However, the involved neural network architectures are largely unoptimized and inefficient with low inference speed, which hinders the realization of real-time imaging. Here, we propose a Neural Architecture Search (NAS) generated Phase Retrieval Net (NAS-PRNet) for accurate and fast phase retrieval. NAS-PRNet is an encoder-decoder style neural network, automatically found from a large neural network architecture search space through NAS. By modifying the differentiable NAS scheme from SparseMask, we learn the optimized skip connections through gradient descent. Specifically, we implement MobileNet-v2 as the encoder and define a synthesized loss that incorporates phase reconstruction loss and network sparsity loss. NAS-PRNet has achieved high-fidelity phase retrieval by achieving a peak Signal-to-Noise Ratio (PSNR) of 36.7 dB and a Structural SIMilarity (SSIM) of 86.6% as tested on interferograms of biological cells. Notably, NAS-PRNet achieves phase retrieval in only 31 ms, representing 15x speedup over the most recent Mamba-UNet with only a slightly lower phase retrieval accuracy.
LGNov 4, 2024Code
Enhancing Graph Neural Networks in Large-scale Traffic Incident Analysis with Concurrency HypothesisXiwen Chen, Sayed Pedram Haeri Boroujeni, Xin Shu et al.
Despite recent progress in reducing road fatalities, the persistently high rate of traffic-related deaths highlights the necessity for improved safety interventions. Leveraging large-scale graph-based nationwide road network data across 49 states in the USA, our study first posits the Concurrency Hypothesis from intuitive observations, suggesting a significant likelihood of incidents occurring at neighboring nodes within the road network. To quantify this phenomenon, we introduce two novel metrics, Average Neighbor Crash Density (ANCD) and Average Neighbor Crash Continuity (ANCC), and subsequently employ them in statistical tests to validate the hypothesis rigorously. Building upon this foundation, we propose the Concurrency Prior (CP) method, a powerful approach designed to enhance the predictive capabilities of general Graph Neural Network (GNN) models in semi-supervised traffic incident prediction tasks. Our method allows GNNs to incorporate concurrent incident information, as mentioned in the hypothesis, via tokenization with negligible extra parameters. The extensive experiments, utilizing real-world data across states and cities in the USA, demonstrate that integrating CP into 12 state-of-the-art GNN architectures leads to significant improvements, with gains ranging from 3% to 13% in F1 score and 1.3% to 9% in AUC metrics. The code is publicly available at https://github.com/xiwenc1/Incident-GNN-CP.
CVNov 15, 2019Code
Cross-modal supervised learning for better acoustic representationsShaoyong Jia, Xin Shu, Yang Yang et al.
Obtaining large-scale human-labeled datasets to train acoustic representation models is a very challenging task. On the contrary, we can easily collect data with machine-generated labels. In this work, we propose to exploit machine-generated labels to learn better acoustic representations, based on the synchronization between vision and audio. Firstly, we collect a large-scale video dataset with 15 million samples, which totally last 16,320 hours. Each video is 3 to 5 seconds in length and annotated automatically by publicly available visual and audio classification models. Secondly, we train various classical convolutional neural networks (CNNs) including VGGish, ResNet 50 and Mobilenet v2. We also make several improvements to VGGish and achieve better results. Finally, we transfer our models on three external standard benchmarks for audio classification task, and achieve significant performance boost over the state-of-the-art results. Models and codes are available at: https://github.com/Deeperjia/vgg-like-audio-models.
IRJan 29
A2RAG: Adaptive Agentic Graph Retrieval for Cost-Aware and Reliable ReasoningJiate Liu, Zebin Chen, Shaobo Qiao et al.
Graph Retrieval-Augmented Generation (Graph-RAG) enhances multihop question answering by organizing corpora into knowledge graphs and routing evidence through relational structure. However, practical deployments face two persistent bottlenecks: (i) mixed-difficulty workloads where one-size-fits-all retrieval either wastes cost on easy queries or fails on hard multihop cases, and (ii) extraction loss, where graph abstraction omits fine-grained qualifiers that remain only in source text. We present A2RAG, an adaptive-and-agentic GraphRAG framework for cost-aware and reliable reasoning. A2RAG couples an adaptive controller that verifies evidence sufficiency and triggers targeted refinement only when necessary, with an agentic retriever that progressively escalates retrieval effort and maps graph signals back to provenance text to remain robust under extraction loss and incomplete graphs. Experiments on HotpotQA and 2WikiMultiHopQA demonstrate that A2RAG achieves +9.9/+11.8 absolute gains in Recall@2, while cutting token consumption and end-to-end latency by about 50% relative to iterative multihop baselines.
LGDec 5, 2025
Sepsis Prediction Using Graph Convolutional Networks over Patient-Feature-Value TripletsBozhi Dan, Di Wu, Ji Xu et al.
In the intensive care setting, sepsis continues to be a major contributor to patient illness and death; however, its timely detection is hindered by the complex, sparse, and heterogeneous nature of electronic health record (EHR) data. We propose Triplet-GCN, a single-branch graph convolutional model that represents each encounter as patient-feature-value triplets, constructs a bipartite EHR graph, and learns patient embeddings via a Graph Convolutional Network (GCN) followed by a lightweight multilayer perceptron (MLP). The pipeline applies type-specific preprocessing -- median imputation and standardization for numeric variables, effect coding for binary features, and mode imputation with low-dimensional embeddings for rare categorical attributes -- and initializes patient nodes with summary statistics, while retaining measurement values on edges to preserve "who measured what and by how much". In a retrospective, multi-center Chinese cohort (N = 648; 70/30 train-test split) drawn from three tertiary hospitals, Triplet-GCN consistently outperforms strong tabular baselines (KNN, SVM, XGBoost, Random Forest) across discrimination and balanced error metrics, yielding a more favorable sensitivity-specificity trade-off and improved overall utility for early warning. These findings indicate that encoding EHR as triplets and propagating information over a patient-feature graph produce more informative patient representations than feature-independent models, offering a simple, end-to-end blueprint for deployable sepsis risk stratification.
LGAug 26, 2025
End to End Autoencoder MLP Framework for Sepsis PredictionHejiang Cai, Di Wu, Ji Xu et al.
Sepsis is a life threatening condition that requires timely detection in intensive care settings. Traditional machine learning approaches, including Naive Bayes, Support Vector Machine (SVM), Random Forest, and XGBoost, often rely on manual feature engineering and struggle with irregular, incomplete time-series data commonly present in electronic health records. We introduce an end-to-end deep learning framework integrating an unsupervised autoencoder for automatic feature extraction with a multilayer perceptron classifier for binary sepsis risk prediction. To enhance clinical applicability, we implement a customized down sampling strategy that extracts high information density segments during training and a non-overlapping dynamic sliding window mechanism for real-time inference. Preprocessed time series data are represented as fixed dimension vectors with explicit missingness indicators, mitigating bias and noise. We validate our approach on three ICU cohorts. Our end-to-end model achieves accuracies of 74.6 percent, 80.6 percent, and 93.5 percent, respectively, consistently outperforming traditional machine learning baselines. These results demonstrate the framework's superior robustness, generalizability, and clinical utility for early sepsis detection across heterogeneous ICU environments.
AIMay 21, 2025
Identification of Probabilities of Causation: A Complete CharacterizationXin Shu, Shuai Wang, Ang Li
Probabilities of causation are fundamental to modern decision-making. Pearl first introduced three binary probabilities of causation, and Tian and Pearl later derived tight bounds for them using Balke's linear programming. The theoretical characterization of probabilities of causation with multi-valued treatments and outcomes has remained unresolved for decades, limiting the scope of causality-based decision-making. In this paper, we resolve this foundational gap by proposing a complete set of representative probabilities of causation and proving that they are sufficient to characterize all possible probabilities of causation within the framework of Structural Causal Models (SCMs). We then formally derive tight bounds for these representative quantities using formal mathematical proofs. Finally, we demonstrate the practical relevance of our results through illustrative toy examples.
IVOct 23, 2024
Predicting total time to compress a video corpus using online inference systemsXin Shu, Vibhoothi Vibhoothi, Anil Kokaram
Predicting the computational cost of compressing/transcoding clips in a video corpus is important for resource management of cloud services and VOD (Video On Demand) providers. Currently, customers of cloud video services are unaware of the cost of transcoding their files until the task is completed. Previous work concentrated on predicting perclip compression time, and thus estimating the cost of video compression. In this work, we propose new Machine Learning (ML) systems which predict cost for the entire corpus instead. This is a more appropriate goal since users are not interested in per-clip cost but instead the cost for the whole corpus. In this work, we evaluate our systems with respect to two video codecs (x264, x265) and a novel high-quality video corpus. We find that the accuracy of aggregate time prediction for a video corpus more than two times better than using per-clip predictions. Furthermore, we present an online inference framework in which we update the ML models as files are processed. A consideration of video compute overhead and appropriate choice of ML predictor for each fraction of corpus completed yields a prediction error of less than 5%. This is approximately two times better than previous work which proposed generalised predictors.