Chengyu Yang

Runpeng Hou, Ziyuan Ye, Chengyu Yang et al.

Nonunion is one of the challenges faced by orthopedics clinics for the technical difficulties and high costs in photographing interosseous capillaries. Segmenting vessels and filling capillaries are critical in understanding the obstacles encountered in capillary growth. However, existing datasets for blood vessel segmentation mainly focus on the large blood vessels of the body, and the lack of labeled capillary image datasets greatly limits the methodological development and applications of vessel segmentation and capillary filling. Here, we present a benchmark dataset, named IFCIS-155, consisting of 155 2D capillary images with segmentation boundaries and vessel fillings annotated by biomedical experts, and 19 large-scale, high-resolution 3D capillary images. To obtain better images of interosseous capillaries, we leverage state-of-the-art immunofluorescence imaging techniques to highlight the rich vascular morphology of interosseous capillaries. We conduct comprehensive experiments to verify the effectiveness of the dataset and the benchmarking deep learning models (\eg UNet/UNet++ and the modified UNet/UNet++). Our work offers a benchmark dataset for training deep learning models for capillary image segmentation and provides a potential tool for future capillary research. The IFCIS-155 dataset and code are all publicly available at \url{https://github.com/ncclabsustech/IFCIS-55}.

Chengyu Yang, Rishik Reddy Yesgari, Chengjun Liu

Rosacea, which is a chronic inflammatory skin condition that manifests with facial redness, papules, and visible blood vessels, often requirs precise and early detection for significantly improving treatment effectiveness. This paper presents new patch-based automatic rosacea detection strategies using the ResNet-18 deep learning framework. The contributions of the proposed strategies come from the following aspects. First, various image pateches are extracted from the facial images of people in different sizes, shapes, and locations. Second, a number of investigation studies are carried out to evaluate how the localized visual information influences the deep learing model performance. Third, thorough experiments are implemented to reveal that several patch-based automatic rosacea detection strategies achieve competitive or superior accuracy and sensitivity than the full-image based methods. And finally, the proposed patch-based strategies, which use only localized patches, inherently preserve patient privacy by excluding any identifiable facial features from the data. The experimental results indicate that the proposed patch-based strategies guide the deep learning model to focus on clinically relevant regions, enhance robustness and interpretability, and protect patient privacy. As a result, the proposed strategies offer practical insights for improving automated dermatological diagnostics.