Mengjie Guo

Mengjie Guo, Hengrong Lan, Changchun Yang et al.

Photoacoustic (PA) imaging is a biomedical imaging modality capable of acquiring high-contrast images of optical absorption at depths much greater than traditional optical imaging techniques. However, practical instrumentation and geometry limit the number of available acoustic sensors surrounding the imaging target, which results in the sparsity of sensor data. Conventional PA image reconstruction methods give severe artifacts when they are applied directly to the sparse PA data. In this paper, we firstly propose to employ a novel signal processing method to make sparse PA raw data more suitable for the neural network, concurrently speeding up image reconstruction. Then we propose Attention Steered Network (AS-Net) for PA reconstruction with multi-feature fusion. AS-Net is validated on different datasets, including simulated photoacoustic data from fundus vasculature phantoms and experimental data from in vivo fish and mice. Notably, the method is also able to eliminate some artifacts present in the ground truth for in vivo data. Results demonstrated that our method provides superior reconstructions at a faster speed.

Tianyang Zhang, Huazhu Fu, Yitian Zhao et al.

Generative Adversarial Networks (GANs) have the capability of synthesizing images, which have been successfully applied to medical image synthesis tasks. However, most of existing methods merely consider the global contextual information and ignore the fine foreground structures, e.g., vessel, skeleton, which may contain diagnostic indicators for medical image analysis. Inspired by human painting procedure, which is composed of stroking and color rendering steps, we propose a Sketching-rendering Unconditional Generative Adversarial Network (SkrGAN) to introduce a sketch prior constraint to guide the medical image generation. In our SkrGAN, a sketch guidance module is utilized to generate a high quality structural sketch from random noise, then a color render mapping is used to embed the sketch-based representations and resemble the background appearances. Experimental results show that the proposed SkrGAN achieves the state-of-the-art results in synthesizing images for various image modalities, including retinal color fundus, X-Ray, Computed Tomography (CT) and Magnetic Resonance Imaging (MRI). In addition, we also show that the performances of medical image segmentation method have been improved by using our synthesized images as data augmentation.