Li Feng

CV
h-index60
20papers
156citations
Novelty51%
AI Score55

20 Papers

CYMay 26
Evaluating Chinese Large Language Models: The Influence of Persona Assignment on Stereotypes and Safeguards

Geng Liu, Li Feng, Carlo Alberto Bono et al.

Recent research has highlighted that assigning specific personas to large language models (LLMs) can significantly increase harmful content generation. However, limited attention has been given to persona-driven toxicity in non-Western contexts, particularly in Chinese-based LLMs. In this paper, we perform a large-scale, cross-model analysis of refusal behavior and persona-driven toxicity amplification across four Chinese LLMs, leveraging a comprehensive dataset of over 1,400,000 generated texts. We identify significant disparities in persona-driven refusal behavior, including systematic gender differences in refusal triggering across the evaluated Chinese LLMs. Furthermore, we provide quantitative evidence of persona-driven toxicity amplification with respect to model default baselines. We show that this amplification--whose magnitude varies substantially across models--is driven by interactions across several factors, involving persona conditioning, prompting strategy, target social group, and model-specific safety mechanisms. Leveraging model-specific regression analyses, we systematically characterize how persona categories, target social groups, and prompt templates independently and jointly shape both refusal behavior and output toxicity. As a complementary case study, we further explore an iterative, evaluator-guided mitigation strategy based on model feedback with an external LLM evaluator, demonstrating that highly toxic outputs can be substantially reduced without costly model retraining. Overall, our findings highlight the importance of culturally contextualized safety evaluations for Chinese-language LLMs and provide a structured framework for assessing persona-induced risks and exploratory mitigation strategies in LLM-generated content.

IVApr 5, 2022
Learning Optimal K-space Acquisition and Reconstruction using Physics-Informed Neural Networks

Wei Peng, Li Feng, Guoying Zhao et al.

The inherent slow imaging speed of Magnetic Resonance Image (MRI) has spurred the development of various acceleration methods, typically through heuristically undersampling the MRI measurement domain known as k-space. Recently, deep neural networks have been applied to reconstruct undersampled k-space data and have shown improved reconstruction performance. While most of these methods focus on designing novel reconstruction networks or new training strategies for a given undersampling pattern, e.g., Cartesian undersampling or Non-Cartesian sampling, to date, there is limited research aiming to learn and optimize k-space sampling strategies using deep neural networks. This work proposes a novel optimization framework to learn k-space sampling trajectories by considering it as an Ordinary Differential Equation (ODE) problem that can be solved using neural ODE. In particular, the sampling of k-space data is framed as a dynamic system, in which neural ODE is formulated to approximate the system with additional constraints on MRI physics. In addition, we have also demonstrated that trajectory optimization and image reconstruction can be learned collaboratively for improved imaging efficiency and reconstruction performance. Experiments were conducted on different in-vivo datasets (e.g., brain and knee images) acquired with different sequences. Initial results have shown that our proposed method can generate better image quality in accelerated MRI than conventional undersampling schemes in Cartesian and Non-Cartesian acquisitions.

HCOct 26, 2023
1D-Touch: NLP-Assisted Coarse Text Selection via a Semi-Direct Gesture

Peiling Jiang, Li Feng, Fuling Sun et al.

Existing text selection techniques on touchscreen focus on improving the control for moving the carets. Coarse-grained text selection on word and phrase levels has not received much support beyond word-snapping and entity recognition. We introduce 1D-Touch, a novel text selection method that complements the carets-based sub-word selection by facilitating the selection of semantic units of words and above. This method employs a simple vertical slide gesture to expand and contract a selection area from a word. The expansion can be by words or by semantic chunks ranging from sub-phrases to sentences. This technique shifts the concept of text selection, from defining a range by locating the first and last words, towards a dynamic process of expanding and contracting a textual semantic entity. To understand the effects of our approach, we prototyped and tested two variants: WordTouch, which offers a straightforward word-by-word expansion, and ChunkTouch, which leverages NLP to chunk text into syntactic units, allowing the selection to grow by semantically meaningful units in response to the sliding gesture. Our evaluation, focused on the coarse-grained selection tasks handled by 1D-Touch, shows a 20% improvement over the default word-snapping selection method on Android.

LGJan 29Code
Sim-MSTNet: sim2real based Multi-task SpatioTemporal Network Traffic Forecasting

Hui Ma, Qingzhong Li, Jin Wang et al.

Network traffic forecasting plays a crucial role in intelligent network operations, but existing techniques often perform poorly when faced with limited data. Additionally, multi-task learning methods struggle with task imbalance and negative transfer, especially when modeling various service types. To overcome these challenges, we propose Sim-MSTNet, a multi-task spatiotemporal network traffic forecasting model based on the sim2real approach. Our method leverages a simulator to generate synthetic data, effectively addressing the issue of poor generalization caused by data scarcity. By employing a domain randomization technique, we reduce the distributional gap between synthetic and real data through bi-level optimization of both sample weighting and model training. Moreover, Sim-MSTNet incorporates attention-based mechanisms to selectively share knowledge between tasks and applies dynamic loss weighting to balance task objectives. Extensive experiments on two open-source datasets show that Sim-MSTNet consistently outperforms state-of-the-art baselines, achieving enhanced accuracy and generalization.

LGFeb 6
AsynDBT: Asynchronous Distributed Bilevel Tuning for efficient In-Context Learning with Large Language Models

Hui Ma, Shaoyu Dou, Ya Liu et al.

With the rapid development of large language models (LLMs), an increasing number of applications leverage cloud-based LLM APIs to reduce usage costs. However, since cloud-based models' parameters and gradients are agnostic, users have to manually or use heuristic algorithms to adjust prompts for intervening LLM outputs, which requiring costly optimization procedures. In-context learning (ICL) has recently emerged as a promising paradigm that enables LLMs to adapt to new tasks using examples provided within the input, eliminating the need for parameter updates. Nevertheless, the advancement of ICL is often hindered by the lack of high-quality data, which is often sensitive and different to share. Federated learning (FL) offers a potential solution by enabling collaborative training of distributed LLMs while preserving data privacy. Despite this issues, previous FL approaches that incorporate ICL have struggled with severe straggler problems and challenges associated with heterogeneous non-identically data. To address these problems, we propose an asynchronous distributed bilevel tuning (AsynDBT) algorithm that optimizes both in-context learning samples and prompt fragments based on the feedback from the LLM, thereby enhancing downstream task performance. Benefiting from its distributed architecture, AsynDBT provides privacy protection and adaptability to heterogeneous computing environments. Furthermore, we present a theoretical analysis establishing the convergence guarantees of the proposed algorithm. Extensive experiments conducted on multiple benchmark datasets demonstrate the effectiveness and efficiency of AsynDBT.

CVAug 11, 2021Code
Learning Oculomotor Behaviors from Scanpath

Beibin Li, Nicholas Nuechterlein, Erin Barney et al.

Identifying oculomotor behaviors relevant for eye-tracking applications is a critical but often challenging task. Aiming to automatically learn and extract knowledge from existing eye-tracking data, we develop a novel method that creates rich representations of oculomotor scanpaths to facilitate the learning of downstream tasks. The proposed stimulus-agnostic Oculomotor Behavior Framework (OBF) model learns human oculomotor behaviors from unsupervised and semi-supervised tasks, including reconstruction, predictive coding, fixation identification, and contrastive learning tasks. The resultant pre-trained OBF model can be used in a variety of applications. Our pre-trained model outperforms baseline approaches and traditional scanpath methods in autism spectrum disorder and viewed-stimulus classification tasks. Ablation experiments further show our proposed method could achieve even better results with larger model sizes and more diverse eye-tracking training datasets, supporting the model's potential for future eye-tracking applications. Open source code: http://github.com/BeibinLi/OBF.

LGNov 12, 2025
Hierarchical Schedule Optimization for Fast and Robust Diffusion Model Sampling

Aihua Zhu, Rui Su, Qinglin Zhao et al.

Diffusion probabilistic models have set a new standard for generative fidelity but are hindered by a slow iterative sampling process. A powerful training-free strategy to accelerate this process is Schedule Optimization, which aims to find an optimal distribution of timesteps for a fixed and small Number of Function Evaluations (NFE) to maximize sample quality. To this end, a successful schedule optimization method must adhere to four core principles: effectiveness, adaptivity, practical robustness, and computational efficiency. However, existing paradigms struggle to satisfy these principles simultaneously, motivating the need for a more advanced solution. To overcome these limitations, we propose the Hierarchical-Schedule-Optimizer (HSO), a novel and efficient bi-level optimization framework. HSO reframes the search for a globally optimal schedule into a more tractable problem by iteratively alternating between two synergistic levels: an upper-level global search for an optimal initialization strategy and a lower-level local optimization for schedule refinement. This process is guided by two key innovations: the Midpoint Error Proxy (MEP), a solver-agnostic and numerically stable objective for effective local optimization, and the Spacing-Penalized Fitness (SPF) function, which ensures practical robustness by penalizing pathologically close timesteps. Extensive experiments show that HSO sets a new state-of-the-art for training-free sampling in the extremely low-NFE regime. For instance, with an NFE of just 5, HSO achieves a remarkable FID of 11.94 on LAION-Aesthetics with Stable Diffusion v2.1. Crucially, this level of performance is attained not through costly retraining, but with a one-time optimization cost of less than 8 seconds, presenting a highly practical and efficient paradigm for diffusion model acceleration.

QUANT-PHMar 5, 2024
Quantum Mixed-State Self-Attention Network

Fu Chen, Qinglin Zhao, Li Feng et al.

Attention mechanisms have revolutionized natural language processing. Combining them with quantum computing aims to further advance this technology. This paper introduces a novel Quantum Mixed-State Self-Attention Network (QMSAN) for natural language processing tasks. Our model leverages quantum computing principles to enhance the effectiveness of self-attention mechanisms. QMSAN uses a quantum attention mechanism based on mixed state, allowing for direct similarity estimation between queries and keys in the quantum domain. This approach leads to more effective attention coefficient calculations. We also propose an innovative quantum positional encoding scheme, implemented through fixed quantum gates within the circuit, improving the model's ability to capture sequence information without additional qubit resources. In numerical experiments of text classification tasks on public datasets, QMSAN outperforms Quantum Self-Attention Neural Network (QSANN). Furthermore, we demonstrate QMSAN's robustness in different quantum noise environments, highlighting its potential for near-term quantum devices.

CVApr 3, 2025
HQViT: Hybrid Quantum Vision Transformer for Image Classification

Hui Zhang, Qinglin Zhao, Mengchu Zhou et al.

Transformer-based architectures have revolutionized the landscape of deep learning. In computer vision domain, Vision Transformer demonstrates remarkable performance on par with or even surpassing that of convolutional neural networks. However, the quadratic computational complexity of its self-attention mechanism poses challenges for classical computing, making model training with high-dimensional input data, e.g., images, particularly expensive. To address such limitations, we propose a Hybrid Quantum Vision Transformer (HQViT), that leverages the principles of quantum computing to accelerate model training while enhancing model performance. HQViT introduces whole-image processing with amplitude encoding to better preserve global image information without additional positional encoding. By leveraging quantum computation on the most critical steps and selectively handling other components in a classical way, we lower the cost of quantum resources for HQViT. The qubit requirement is minimized to $O(log_2N)$ and the number of parameterized quantum gates is only $O(log_2d)$, making it well-suited for Noisy Intermediate-Scale Quantum devices. By offloading the computationally intensive attention coefficient matrix calculation to the quantum framework, HQViT reduces the classical computational load by $O(T^2d)$. Extensive experiments across various computer vision datasets demonstrate that HQViT outperforms existing models, achieving a maximum improvement of up to $10.9\%$ (on the MNIST 10-classification task) over the state of the art. This work highlights the great potential to combine quantum and classical computing to cope with complex image classification tasks.

QUANT-PHMar 24, 2025
Quantum Complex-Valued Self-Attention Model

Fu Chen, Qinglin Zhao, Li Feng et al.

Self-attention has revolutionized classical machine learning, yet existing quantum self-attention models underutilize quantum states' potential due to oversimplified or incomplete mechanisms. To address this limitation, we introduce the Quantum Complex-Valued Self-Attention Model (QCSAM), the first framework to leverage complex-valued similarities, which captures amplitude and phase relationships between quantum states more comprehensively. To achieve this, QCSAM extends the Linear Combination of Unitaries (LCUs) into the Complex LCUs (CLCUs) framework, enabling precise complex-valued weighting of quantum states and supporting quantum multi-head attention. Experiments on MNIST and Fashion-MNIST show that QCSAM outperforms recent quantum self-attention models, including QKSAN, QSAN, and GQHAN. With only 4 qubits, QCSAM achieves 100% and 99.2% test accuracies on MNIST and Fashion-MNIST, respectively. Furthermore, we evaluate scalability across 3-8 qubits and 2-4 class tasks, while ablation studies validate the advantages of complex-valued attention weights over real-valued alternatives. This work advances quantum machine learning by enhancing the expressiveness and precision of quantum self-attention in a way that aligns with the inherent complexity of quantum mechanics.

LGMar 27, 2024
IIP-Mixer:Intra-Inter Patch Mixing Architecture for Battery Remaining Useful Life Prediction

Guangzai Ye, Li Feng, Jianlan Guo et al.

Accurately estimating the Remaining Useful Life (RUL) of lithium-ion batteries is crucial for maintaining the safe and stable operation of rechargeable battery management systems. However, this task is often challenging due to the complex temporal dynamics involved. Recently, attention-based networks, such as Transformers and Informer, have been the popular architecture in time series forecasting. Despite their effectiveness, these models with abundant parameters necessitate substantial training time to unravel temporal patterns. To tackle these challenges, we propose a simple MLP-Mixer-based architecture named 'Intra-Inter Patch Mixer' (IIP-Mixer), which is an architecture based exclusively on multi-layer perceptrons (MLPs), extracting information by mixing operations along both intra-patch and inter-patch dimensions for battery RUL prediction. The proposed IIP-Mixer comprises parallel dual-head mixer layers: the intra-patch mixing MLP, capturing local temporal patterns in the short-term period, and the inter-patch mixing MLP, capturing global temporal patterns in the long-term period. Notably, to address the varying importance of features in RUL prediction, we introduce a weighted loss function in the MLP-Mixer-based architecture, marking the first time such an approach has been employed. Our experiments demonstrate that IIP-Mixer achieves competitive performance in battery RUL prediction, outperforming other popular time-series frameworks

IRDec 15, 2025
Misinformation Exposure in the Chinese Web: A Cross-System Evaluation of Search Engines, LLMs, and AI Overviews

Geng Liu, Junjie Mu, Li Feng et al.

Large Language Models (LLMs) are increasingly integrated into search services, providing direct answers that can reduce users' reliance on traditional result pages. Yet their factual reliability in non-English web ecosystems remains poorly understood, particularly when answering real user queries. We introduce a fact-checking dataset of 12~161 Chinese Yes/No questions derived from real-world online search logs and develop a unified evaluation pipeline to compare three information-access paradigms: traditional search engines, standalone LLMs, and AI-generated overview modules. Our analysis reveals substantial differences in factual accuracy and topic-level variability across systems. By combining this performance with real-world Baidu Index statistics, we further estimate potential exposure to incorrect factual information of Chinese users across regions. These findings highlight structural risks in AI-mediated search and underscore the need for more reliable and transparent information-access tools for the digital world.

LGNov 23, 2025
PeriodNet: Boosting the Potential of Attention Mechanism for Time Series Forecasting

Bowen Zhao, Huanlai Xing, Zhiwen Xiao et al.

The attention mechanism has demonstrated remarkable potential in sequence modeling, exemplified by its successful application in natural language processing with models such as Bidirectional Encoder Representations from Transformers (BERT) and Generative Pre-trained Transformer (GPT). Despite these advancements, its utilization in time series forecasting (TSF) has yet to meet expectations. Exploring a better network structure for attention in TSF holds immense significance across various domains. In this paper, we present PeriodNet with a brand new structure to forecast univariate and multivariate time series. PeriodNet incorporates period attention and sparse period attention mechanism for analyzing adjacent periods. It enhances the mining of local characteristics, periodic patterns, and global dependencies. For efficient cross-variable modeling, we introduce an iterative grouping mechanism which can directly reduce the cross-variable redundancy. To fully leverage the extracted features on the encoder side, we redesign the entire architecture of the vanilla Transformer and propose a period diffuser for precise multi-period prediction. Through comprehensive experiments conducted on eight datasets, we demonstrate that PeriodNet outperforms six state-of-the-art models in both univariate and multivariate TSF scenarios in terms of mean square error and mean absolute error. In particular, PeriodNet achieves a relative improvement of 22% when forecasting time series with a length of 720, in comparison to other models based on the conventional encoder-decoder Transformer architecture.

IVJul 18, 2025
Self-Supervised Joint Reconstruction and Denoising of T2-Weighted PROPELLER MRI of the Lungs at 0.55T

Jingjia Chen, Haoyang Pei, Christoph Maier et al.

Purpose: This study aims to improve 0.55T T2-weighted PROPELLER lung MRI through a self-supervised joint reconstruction and denoising model. Methods: T2-weighted 0.55T lung MRI dataset including 44 patients with previous covid infection were used. A self-supervised learning framework was developed, where each blade of the PROPELLER acquisition was split along the readout direction into two partitions. One subset trains the unrolled reconstruction network, while the other subset is used for loss calculation, enabling self-supervised training without clean targets and leveraging matched noise statistics for denoising. For comparison, Marchenko-Pastur Principal Component Analysis (MPPCA) was performed along the coil dimension, followed by conventional parallel imaging reconstruction. The quality of the reconstructed lung MRI was assessed visually by two experienced radiologists independently. Results: The proposed self-supervised model improved the clarity and structural integrity of the lung images. For cases with available CT scans, the reconstructed images demonstrated strong alignment with corresponding CT images. Additionally, the proposed model enables further scan time reduction by requiring only half the number of blades. Reader evaluations confirmed that the proposed method outperformed MPPCA-denoised images across all categories (Wilcoxon signed-rank test, p<0.001), with moderate inter-reader agreement (weighted Cohen's kappa=0.55; percentage of exact and within +/-1 point agreement=91%). Conclusion: By leveraging intrinsic structural redundancies between two disjoint splits of k-space subsets, the proposed self-supervised learning model effectively reconstructs the image while suppressing the noise for 0.55T T2-weighted lung MRI with PROPELLER sampling.

IVMay 9, 2025
Hybrid Learning: A Novel Combination of Self-Supervised and Supervised Learning for MRI Reconstruction without High-Quality Training Reference

Haoyang Pei, Ding Xia, Xiang Xu et al.

Purpose: Deep learning has demonstrated strong potential for MRI reconstruction, but conventional supervised learning methods require high-quality reference images, which are often unavailable in practice. Self-supervised learning offers an alternative, yet its performance degrades at high acceleration rates. To overcome these limitations, we propose hybrid learning, a novel two-stage training framework that combines self-supervised and supervised learning for robust image reconstruction. Methods: Hybrid learning is implemented in two sequential stages. In the first stage, self-supervised learning is employed to generate improved images from noisy or undersampled reference data. These enhanced images then serve as pseudo-ground truths for the second stage, which uses supervised learning to refine reconstruction performance and support higher acceleration rates. We evaluated hybrid learning in two representative applications: (1) accelerated 0.55T spiral-UTE lung MRI using noisy reference data, and (2) 3D T1 mapping of the brain without access to fully sampled ground truth. Results: For spiral-UTE lung MRI, hybrid learning consistently improved image quality over both self-supervised and conventional supervised methods across different acceleration rates, as measured by SSIM and NMSE. For 3D T1 mapping, hybrid learning achieved superior T1 quantification accuracy across a wide dynamic range, outperforming self-supervised learning in all tested conditions. Conclusions: Hybrid learning provides a practical and effective solution for training deep MRI reconstruction networks when only low-quality or incomplete reference data are available. It enables improved image quality and accurate quantitative mapping across different applications and field strengths, representing a promising technique toward broader clinical deployment of deep learning-based MRI.

IVJan 16, 2025
Domain-conditioned and Temporal-guided Diffusion Modeling for Accelerated Dynamic MRI Reconstruction

Liping Zhang, Iris Yuwen Zhou, Sydney B. Montesi et al.

Purpose: To propose a domain-conditioned and temporal-guided diffusion modeling method, termed dynamic Diffusion Modeling (dDiMo), for accelerated dynamic MRI reconstruction, enabling diffusion process to characterize spatiotemporal information for time-resolved multi-coil Cartesian and non-Cartesian data. Methods: The dDiMo framework integrates temporal information from time-resolved dimensions, allowing for the concurrent capture of intra-frame spatial features and inter-frame temporal dynamics in diffusion modeling. It employs additional spatiotemporal ($x$-$t$) and self-consistent frequency-temporal ($k$-$t$) priors to guide the diffusion process. This approach ensures precise temporal alignment and enhances the recovery of fine image details. To facilitate a smooth diffusion process, the nonlinear conjugate gradient algorithm is utilized during the reverse diffusion steps. The proposed model was tested on two types of MRI data: Cartesian-acquired multi-coil cardiac MRI and Golden-Angle-Radial-acquired multi-coil free-breathing lung MRI, across various undersampling rates. Results: dDiMo achieved high-quality reconstructions at various acceleration factors, demonstrating improved temporal alignment and structural recovery compared to other competitive reconstruction methods, both qualitatively and quantitatively. This proposed diffusion framework exhibited robust performance in handling both Cartesian and non-Cartesian acquisitions, effectively reconstructing dynamic datasets in cardiac and lung MRI under different imaging conditions. Conclusion: This study introduces a novel diffusion modeling method for dynamic MRI reconstruction.

CVMay 9, 2021
Interaction Detection Between Vehicles and Vulnerable Road Users: A Deep Generative Approach with Attention

Hao Cheng, Li Feng, Hailong Liu et al.

Intersections where vehicles are permitted to turn and interact with vulnerable road users (VRUs) like pedestrians and cyclists are among some of the most challenging locations for automated and accurate recognition of road users' behavior. In this paper, we propose a deep conditional generative model for interaction detection at such locations. It aims to automatically analyze massive video data about the continuity of road users' behavior. This task is essential for many intelligent transportation systems such as traffic safety control and self-driving cars that depend on the understanding of road users' locomotion. A Conditional Variational Auto-Encoder based model with Gaussian latent variables is trained to encode road users' behavior and perform probabilistic and diverse predictions of interactions. The model takes as input the information of road users' type, position and motion automatically extracted by a deep learning object detector and optical flow from videos, and generates frame-wise probabilities that represent the dynamics of interactions between a turning vehicle and any VRUs involved. The model's efficacy was validated by testing on real--world datasets acquired from two different intersections. It achieved an F1-score above 0.96 at a right--turn intersection in Germany and 0.89 at a left--turn intersection in Japan, both with very busy traffic flows.

ROApr 7, 2021
Few-Shot Meta-Learning on Point Cloud for Semantic Segmentation

Xudong Li, Li Feng, Lei Li et al.

The promotion of construction robots can solve the problem of human resource shortage and improve the quality of decoration. To help the construction robots obtain environmental information, we need to use 3D point cloud, which is widely used in robotics, autonomous driving, and so on. With a good understanding of environmental information, construction robots can work better. However, the dynamic changes of 3D point cloud data may bring difficulties for construction robots to understand environmental information, such as when construction robots renovate houses. The paper proposes a semantic segmentation method for point cloud based on meta-learning. The method includes a basic learning module and a meta-learning module. The basic learning module is responsible for learning data features and evaluating the model, while the meta-learning module is responsible for updating the parameters of the model and improving the model generalization ability. In our work, we pioneered the method of producing datasets for meta-learning in 3D scenes, as well as demonstrated that the Model-Agnostic Meta-Learning (MAML) algorithm can be applied to process 3D point cloud data. At the same time, experiments show that our method can allow the model to be quickly applied to new environments with a few samples. Our method has important applications.

CVDec 8, 2018
SANTIS: Sampling-Augmented Neural neTwork with Incoherent Structure for MR image reconstruction

Fang Liu, Lihua Chen, Richard Kijowski et al.

Deep learning holds great promise in the reconstruction of undersampled Magnetic Resonance Imaging (MRI) data, providing new opportunities to escalate the performance of rapid MRI. In existing deep learning-based reconstruction methods, supervised training is performed using artifact-free reference images and their corresponding undersampled pairs. The undersampled images are generated by a fixed undersampling pattern in the training, and the trained network is then applied to reconstruct new images acquired with the same pattern in the inference. While such a training strategy can maintain a favorable reconstruction for a pre-selected undersampling pattern, the robustness of the trained network against any discrepancy of undersampling schemes is typically poor. We developed a novel deep learning-based reconstruction framework called SANTIS for efficient MR image reconstruction with improved robustness against sampling pattern discrepancy. SANTIS uses a data cycle-consistent adversarial network combining efficient end-to-end convolutional neural network mapping, data fidelity enforcement and adversarial training for reconstructing accelerated MR images more faithfully. A training strategy employing sampling augmentation with extensive variation of undersampling patterns was further introduced to promote the robustness of the trained network. Compared to conventional reconstruction and standard deep learning methods, SANTIS achieved consistent better reconstruction performance, with lower errors, greater image sharpness and higher similarity with respect to the reference regardless of the undersampling patterns during inference. This novel concept behind SANTIS can particularly be useful towards improving the robustness of deep learning-based image reconstruction against discrepancy between training and evaluation, which is currently an important but less studied open question.

CVSep 2, 2018
MANTIS: Model-Augmented Neural neTwork with Incoherent k-space Sampling for efficient MR T2 mapping

Fang Liu, Li Feng, Richard Kijowski

Quantitative mapping of magnetic resonance (MR) parameters have been shown as valuable methods for improved assessment of a range of diseases. Due to the need to image an anatomic structure multiple times, parameter mapping usually requires long scan times compared to conventional static imaging. Therefore, accelerated parameter mapping is highly-desirable and remains a topic of great interest in the MR research community. While many recent deep learning methods have focused on highly efficient image reconstruction for conventional static MR imaging, applications of deep learning for dynamic imaging and in particular accelerated parameter mapping have been limited. The purpose of this work was to develop and evaluate a novel deep learning-based reconstruction framework called Model-Augmented Neural neTwork with Incoherent k-space Sampling (MANTIS) for efficient MR parameter mapping. Our approach combines end-to-end CNN mapping with k-space consistency using the concept of cyclic loss to further enforce data and model fidelity. Incoherent k-space sampling is used to improve reconstruction performance. A physical model is incorporated into the proposed framework, so that the parameter maps can be efficiently estimated directly from undersampled images. The performance of MANTIS was demonstrated for the spin-spin relaxation time (T2) mapping of the knee joint. Compared to conventional reconstruction approaches that exploited image sparsity, MANTIS yielded lower errors and higher similarity with respect to the reference in the T2 estimation. Our study demonstrated that the proposed MANTIS framework, with a combination of end-to-end CNN mapping, signal model-augmented data consistency, and incoherent k-space sampling, represents a promising approach for efficient MR parameter mapping. MANTIS can potentially be extended to other types of parameter mapping with appropriate models.