Wenbin Lei

Jia Wei, Yun Li, Meiyu Qiu et al.

Laryngo-pharyngeal cancer (LPC) is a highly fatal malignant disease affecting the head and neck region. Previous studies on endoscopic tumor detection, particularly those leveraging dual-branch network architectures, have shown significant advancements in tumor detection. These studies highlight the potential of dual-branch networks in improving diagnostic accuracy by effectively integrating global and local (lesion) feature extraction. However, they are still limited in their capabilities to accurately locate the lesion region and capture the discriminative feature information between the global and local branches. To address these issues, we propose a novel SAM-guided fusion network (SAM-FNet), a dual-branch network for laryngo-pharyngeal tumor detection. By leveraging the powerful object segmentation capabilities of the Segment Anything Model (SAM), we introduce the SAM into the SAM-FNet to accurately segment the lesion region. Furthermore, we propose a GAN-like feature optimization (GFO) module to capture the discriminative features between the global and local branches, enhancing the fusion feature complementarity. Additionally, we collect two LPC datasets from the First Affiliated Hospital (FAHSYSU) and the Sixth Affiliated Hospital (SAHSYSU) of Sun Yat-sen University. The FAHSYSU dataset is used as the internal dataset for training the model, while the SAHSYSU dataset is used as the external dataset for evaluating the model's performance. Extensive experiments on both datasets of FAHSYSU and SAHSYSU demonstrate that the SAM-FNet can achieve competitive results, outperforming the state-of-the-art counterparts. The source code of SAM-FNet is available at the URL of https://github.com/VVJia/SAM-FNet.

Xiao Song, Jiafan Liu, Yun Li et al.

Radiology Report Generation (RRG) draws attention as a vision-and-language interaction of biomedical fields. Previous works inherited the ideology of traditional language generation tasks, aiming to generate paragraphs with high readability as reports. Despite significant progress, the independence between diseases-a specific property of RRG-was neglected, yielding the models being confused by the co-occurrence of diseases brought on by the biased data distribution, thus generating inaccurate reports. In this paper, to rethink this issue, we first model the causal effects between the variables from a causal perspective, through which we prove that the co-occurrence relationships between diseases on the biased distribution function as confounders, confusing the accuracy through two backdoor paths, i.e. the Joint Vision Coupling and the Conditional Sequential Coupling. Then, we proposed a novel model-agnostic counterfactual augmentation method that contains two strategies, i.e. the Prototype-based Counterfactual Sample Synthesis (P-CSS) and the Magic-Cube-like Counterfactual Report Reconstruction (Cube), to intervene the backdoor paths, thus enhancing the accuracy and generalization of RRG models. Experimental results on the widely used MIMIC-CXR dataset demonstrate the effectiveness of our proposed method. Additionally, a generalization performance is evaluated on IU X-Ray dataset, which verifies our work can effectively reduce the impact of co-occurrences caused by different distributions on the results.

Meiyu Qiu, Yun Li, Wenjun Huang et al.

Laryngeal cancer is a malignant disease with a high morality rate in otorhinolaryngology, posing an significant threat to human health. Traditionally larygologists manually visual-inspect laryngeal cancer in laryngoscopic videos, which is quite time-consuming and subjective. In this study, we propose a novel automatic framework via 3D-large-scale pretrained models termed 3D-LSPTM for laryngeal cancer detection. Firstly, we collect 1,109 laryngoscopic videos from the First Affiliated Hospital Sun Yat-sen University with the approval of the Ethics Committee. Then we utilize the 3D-large-scale pretrained models of C3D, TimeSformer, and Video-Swin-Transformer, with the merit of advanced featuring videos, for laryngeal cancer detection with fine-tuning techniques. Extensive experiments show that our proposed 3D-LSPTM can achieve promising performance on the task of laryngeal cancer detection. Particularly, 3D-LSPTM with the backbone of Video-Swin-Transformer can achieve 92.4% accuracy, 95.6% sensitivity, 94.1% precision, and 94.8% F_1.

Lingcong Cai, Yun Li, Xiaomao Fan et al.

The segmentation of endoscopic images plays a vital role in computer-aided diagnosis and treatment. The advancements in deep learning have led to the employment of numerous models for endoscopic tumor segmentation, achieving promising segmentation performance. Despite recent advancements, precise segmentation remains challenging due to limited annotations and the issue of low contrast. To address these issues, we propose a novel semi-supervised segmentation framework termed LoCo via low-contrast-enhanced contrastive learning (LCC). This innovative approach effectively harnesses the vast amounts of unlabeled data available for endoscopic image segmentation, improving both accuracy and robustness in the segmentation process. Specifically, LCC incorporates two advanced strategies to enhance the distinctiveness of low-contrast pixels: inter-class contrast enhancement (ICE) and boundary contrast enhancement (BCE), enabling models to segment low-contrast pixels among malignant tumors, benign tumors, and normal tissues. Additionally, a confidence-based dynamic filter (CDF) is designed for pseudo-label selection, enhancing the utilization of generated pseudo-labels for unlabeled data with a specific focus on minority classes. Extensive experiments conducted on two public datasets, as well as a large proprietary dataset collected over three years, demonstrate that LoCo achieves state-of-the-art results, significantly outperforming previous methods. The source code of LoCo is available at the URL of \href{https://github.com/AnoK3111/LoCo}{https://github.com/AnoK3111/LoCo}.

Jia Wei, Yun Li, Xiaomao Fan et al.

Laryngo-pharyngeal cancer (LPC) is a highly lethal malignancy in the head and neck region. Recent advancements in tumor detection, particularly through dual-branch network architectures, have significantly improved diagnostic accuracy by integrating global and local feature extraction. However, challenges remain in accurately localizing lesions and fully capitalizing on the complementary nature of features within these branches. To address these issues, we propose SAM-Swin, an innovative SAM-driven Dual-Swin Transformer for laryngo-pharyngeal tumor detection. This model leverages the robust segmentation capabilities of the Segment Anything Model 2 (SAM2) to achieve precise lesion segmentation. Meanwhile, we present a multi-scale lesion-aware enhancement module (MS-LAEM) designed to adaptively enhance the learning of nuanced complementary features across various scales, improving the quality of feature extraction and representation. Furthermore, we implement a multi-scale class-aware guidance (CAG) loss that delivers multi-scale targeted supervision, thereby enhancing the model's capacity to extract class-specific features. To validate our approach, we compiled three LPC datasets from the First Affiliated Hospital (FAHSYSU), the Sixth Affiliated Hospital (SAHSYSU) of Sun Yat-sen University, and Nanfang Hospital of Southern Medical University (NHSMU). The FAHSYSU dataset is utilized for internal training, while the SAHSYSU and NHSMU datasets serve for external evaluation. Extensive experiments demonstrate that SAM-Swin outperforms state-of-the-art methods, showcasing its potential for advancing LPC detection and improving patient outcomes. The source code of SAM-Swin is available at the URL of \href{https://github.com/VVJia/SAM-Swin}{https://github.com/VVJia/SAM-Swin}.

Liuwang Kang, Fan Wang, Yuzhang Huang et al.

Mission-critical healthcare applications including real-time intensive care monitoring, ambulance-to-hospital orchestration, and distributed medical imaging inference require workflow-level, time-bounded coordination across heterogeneous devices, edge servers, and network control entities. While current 3GPP and O-RAN standards excel at per-device control and quality-of-service enforcement, they do not natively expose abstractions for workflow-level coordination under strict clinical timing constraints, leaving this capability to fragile, application-specific overlays. This article outlines the Collective Adaptive Intelligence Plane (CAIP) as a standards-aligned coordination framework that addresses this abstraction gap without introducing new protocol layers. CAIP is realized through minimal, backward-compatible coordination profiles anchored to existing RRC, QoS/SDAP, and O-RAN E2 interfaces, enabling workflow-scoped coordination context binding, deadline-aware coordination pacing, semantic flow association, and privacy-preserving data locality across distributed clinical entities. We analyze the structural limitations of existing standards, present a concrete interface mapping to 3GPP and O-RAN mechanisms, illustrate deployment through a representative ICU coordination scenario, and outline a phased standardization roadmap from proof-of-concept xApp deployment to AI-native 6G specification evolution. The proposed framework is incrementally deployable on current 5G Advanced infrastructure and provides a principled migration path toward workflow-level coordination abstraction as a first-class capability in future 6G healthcare networks.

Junhao Wu, Yun Li, Junhao Li et al.

Accurate segmentation of laryngo-pharyngeal tumors is crucial for precise diagnosis and effective treatment planning. However, traditional single-modality imaging methods often fall short of capturing the complex anatomical and pathological features of these tumors. In this study, we present an innovative multi-modality representation learning framework based on the `Align-Disentangle-Fusion' mechanism that seamlessly integrates 2D White Light Imaging (WLI) and Narrow Band Imaging (NBI) pairs to enhance segmentation performance. A cornerstone of our approach is multi-scale distribution alignment, which mitigates modality discrepancies by aligning features across multiple transformer layers. Furthermore, a progressive feature disentanglement strategy is developed with the designed preliminary disentanglement and disentangle-aware contrastive learning to effectively separate modality-specific and shared features, enabling robust multimodal contrastive learning and efficient semantic fusion. Comprehensive experiments on multiple datasets demonstrate that our method consistently outperforms state-of-the-art approaches, achieving superior accuracy across diverse real clinical scenarios.