Seok-Bum Ko

Pouya Shiri, Xin Yi, Neel P. Mistry et al.

Contrast-enhanced computed tomography (CT) imaging is essential for diagnosing and monitoring thoracic diseases, including aortic pathologies. However, contrast agents pose risks such as nephrotoxicity and allergic-like reactions. The ability to generate high-fidelity synthetic contrast-enhanced CT angiography (CTA) images without contrast administration would be transformative, enhancing patient safety and accessibility while reducing healthcare costs. In this study, we propose the first bridge diffusion-based solution for synthesizing contrast-enhanced CTA images from non-contrast CT scans. Our approach builds on the Slice-Consistent Brownian Bridge Diffusion Model (SC-BBDM), leveraging its ability to model complex mappings while maintaining consistency across slices. Unlike conventional slice-wise synthesis methods, our framework preserves full 3D anatomical integrity while operating in a high-resolution 2D fashion, allowing seamless volumetric interpretation under a low memory budget. To ensure robust spatial alignment, we implement a comprehensive preprocessing pipeline that includes resampling, registration using the Symmetric Normalization method, and a sophisticated dilated segmentation mask to extract the aorta and surrounding structures. We create two datasets from the Coltea-Lung dataset: one containing only the aorta and another including both the aorta and heart, enabling a detailed analysis of anatomical context. We compare our approach against baseline methods on both datasets, demonstrating its effectiveness in preserving vascular structures while enhancing contrast fidelity.

Sina Soleimani-Fard, Won Gi Jeong, Francis Ferri Ripalda et al.

To automatically detect Anterior Mediastinum Lesions (AMLs) in the Anterior Mediastinum (AM), the primary requirement will be an automatic segmentation model specifically designed for the AM. The prevalence of AML is extremely low, making it challenging to conduct screening research similar to lung cancer screening. Retrospectively reviewing chest CT scans over a specific period to investigate the prevalence of AML requires substantial time. Therefore, developing an Artificial Intelligence (AI) model to find location of AM helps radiologist to enhance their ability to manage workloads and improve diagnostic accuracy for AMLs. In this paper, we introduce a U-shaped structure network to segment AM. Two attention mechanisms were used for maintaining long-range dependencies and localization. In order to have the potential of Multi-Head Self-Attention (MHSA) and a lightweight network, we designed a parallel MHSA named Wide-MHSA (W-MHSA). Maintaining long-range dependencies is crucial for segmentation when we upsample feature maps. Therefore, we designed a Dilated Depth-Wise Parallel Path connection (DDWPP) for this purpose. In order to design a lightweight architecture, we introduced an expanding convolution block and combine it with the proposed W-MHSA for feature extraction in the encoder part of the proposed U-shaped network. The proposed network was trained on 2775 AM cases, which obtained an average Dice Similarity Coefficient (DSC) of 87.83%, mean Intersection over Union (IoU) of 79.16%, and Sensitivity of 89.60%. Our proposed architecture exhibited superior segmentation performance compared to the most advanced segmentation networks, such as Trans Unet, Attention Unet, Res Unet, and Res Unet++.

Arman Haghanifar, Mahdiyar Molahasani Majdabadi, Seok-Bum Ko

Dental caries is one of the most chronic diseases involving the majority of the population during their lifetime. Caries lesions are typically diagnosed by radiologists relying only on their visual inspection to detect via dental x-rays. In many cases, dental caries is hard to identify using x-rays and can be misinterpreted as shadows due to different reasons such as low image quality. Hence, developing a decision support system for caries detection has been a topic of interest in recent years. Here, we propose an automatic diagnosis system to detect dental caries in Panoramic images for the first time, to the best of authors' knowledge. The proposed model benefits from various pretrained deep learning models through transfer learning to extract relevant features from x-rays and uses a capsule network to draw prediction results. On a dataset of 470 Panoramic images used for features extraction, including 240 labeled images for classification, our model achieved an accuracy score of 86.05\% on the test set. The obtained score demonstrates acceptable detection performance and an increase in caries detection speed, as long as the challenges of using Panoramic x-rays of real patients are taken into account. Among images with caries lesions in the test set, our model acquired recall scores of 69.44\% and 90.52\% for mild and severe ones, confirming the fact that severe caries spots are more straightforward to detect and efficient mild caries detection needs a more robust and larger dataset. Considering the novelty of current research study as using Panoramic images, this work is a step towards developing a fully automated efficient decision support system to assist domain experts.