Eva Kaushik

Rohit Kaushik, Eva Kaushik

Cardiovascular disease (CVD) continues to be the major cause of death globally, calling for predictive models that not only handle diverse and high-dimensional biomedical signals but also maintain interpretability and privacy. We create a single multimodal learning framework that integrates cross modal transformers with graph neural networks and causal representation learning to measure personalized CVD risk. The model combines genomic variation, cardiac MRI, ECG waveforms, wearable streams, and structured EHR data to predict risk while also implementing causal invariance constraints across different clinical subpopulations. To maintain transparency, we employ SHAP based feature attribution, counterfactual explanations and causal latent alignment for understandable risk factors. Besides, we position the design in a federated, privacy, preserving optimization protocol and establish rules for convergence, calibration and uncertainty quantification under distributional shift. Experimental studies based on large-scale biobank and multi institutional datasets reveal state discrimination and robustness, exhibiting fair performance across demographic strata and clinically distinct cohorts. This study paves the way for a principled approach to clinically trustworthy, interpretable and privacy respecting CVD prediction at the population level.

Rohit Kaushik, Eva Kaushik

The rapid growth of dermatological imaging and mobile diagnostic tools calls for systems that not only demonstrate empirical performance but also provide strong theoretical guarantees. Deep learning models have shown high predictive accuracy; however, they are often criticized for lacking well, calibrated uncertainty estimates without which these models are hardly deployable in a clinical setting. To this end, we present the Conformal Bayesian Dermatological Classifier (CBDC), a well, founded framework that combines Statistical Learning Theory, Topological Data Analysis (TDA), and Bayesian Conformal Inference. CBDC offers distribution, dependent generalization bounds that reflect dermatological variability, proves a topological stability theorem that guarantees the invariance of convolutional neural network embeddings under photometric and morphological perturbations and provides finite conformal coverage guarantees for trustworthy uncertainty quantification. Through exhaustive experiments on the HAM10000, PH2, and ISIC 2020 datasets, we show that CBDC not only attains classification accuracy but also generates calibrated predictions that are interpretable from a clinical perspective. This research constitutes a theoretical and practical leap for deep dermatological diagnostics, thereby opening the machine learning theory clinical applicability interface.