Sifan Wu

Zhenguang Liu, Sifan Wu, Chejian Xu et al.

One compelling application of artificial intelligence is to generate a video of a target person performing arbitrary desired motion (from a source person). While the state-of-the-art methods are able to synthesize a video demonstrating similar broad stroke motion details, they are generally lacking in texture details. A pertinent manifestation appears as distorted face, feet, and hands, and such flaws are very sensitively perceived by human observers. Furthermore, current methods typically employ GANs with a L2 loss to assess the authenticity of the generated videos, inherently requiring a large amount of training samples to learn the texture details for adequate video generation. In this work, we tackle these challenges from three aspects: 1) We disentangle each video frame into foreground (the person) and background, focusing on generating the foreground to reduce the underlying dimension of the network output. 2) We propose a theoretically motivated Gromov-Wasserstein loss that facilitates learning the mapping from a pose to a foreground image. 3) To enhance texture details, we encode facial features with geometric guidance and employ local GANs to refine the face, feet, and hands. Extensive experiments show that our method is able to generate realistic target person videos, faithfully copying complex motions from a source person.

Huan Zhang, Yizhan Li, Wenhao Huang et al. · mila

The convergence of artificial intelligence and materials science presents a transformative opportunity, but achieving true acceleration in discovery requires moving beyond task-isolated, fine-tuned models toward agentic systems that plan, act, and learn across the full discovery loop. This survey advances a unique pipeline-centric view that spans from corpus curation and pretraining, through domain adaptation and instruction tuning, to goal-conditioned agents interfacing with simulation and experimental platforms. Unlike prior reviews, we treat the entire process as an end-to-end system to be optimized for tangible discovery outcomes rather than proxy benchmarks. This perspective allows us to trace how upstream design choices-such as data curation and training objectives-can be aligned with downstream experimental success through effective credit assignment. To bridge communities and establish a shared frame of reference, we first present an integrated lens that aligns terminology, evaluation, and workflow stages across AI and materials science. We then analyze the field through two focused lenses: From the AI perspective, the survey details LLM strengths in pattern recognition, predictive analytics, and natural language processing for literature mining, materials characterization, and property prediction; from the materials science perspective, it highlights applications in materials design, process optimization, and the acceleration of computational workflows via integration with external tools (e.g., DFT, robotic labs). Finally, we contrast passive, reactive approaches with agentic design, cataloging current contributions while motivating systems that pursue long-horizon goals with autonomy, memory, and tool use. This survey charts a practical roadmap towards autonomous, safety-aware LLM agents aimed at discovering novel and useful materials.

Haoming Chen, Runyang Feng, Sifan Wu et al.

Human pose estimation aims at localizing human anatomical keypoints or body parts in the input data (e.g., images, videos, or signals). It forms a crucial component in enabling machines to have an insightful understanding of the behaviors of humans, and has become a salient problem in computer vision and related fields. Deep learning techniques allow learning feature representations directly from the data, significantly pushing the performance boundary of human pose estimation. In this paper, we reap the recent achievements of 2D human pose estimation methods and present a comprehensive survey. Briefly, existing approaches put their efforts in three directions, namely network architecture design, network training refinement, and post processing. Network architecture design looks at the architecture of human pose estimation models, extracting more robust features for keypoint recognition and localization. Network training refinement tap into the training of neural networks and aims to improve the representational ability of models. Post processing further incorporates model-agnostic polishing strategies to improve the performance of keypoint detection. More than 200 research contributions are involved in this survey, covering methodological frameworks, common benchmark datasets, evaluation metrics, and performance comparisons. We seek to provide researchers with a more comprehensive and systematic review on human pose estimation, allowing them to acquire a grand panorama and better identify future directions.

Qihao Shen, Jiaxing Xuan, Zhenguang Liu et al.

Advanced deepfake technologies are blurring the lines between real and fake, presenting both revolutionary opportunities and alarming threats. While it unlocks novel applications in fields like entertainment and education, its malicious use has sparked urgent ethical and societal concerns ranging from identity theft to the dissemination of misinformation. To tackle these challenges, feature analysis using frequency features has emergedas a promising direction for deepfake detection. However, oneaspect that has been overlooked so far is that existing methodstend to concentrate on one or a few specific frequency domains,which risks overfitting to particular artifacts and significantlyundermines their robustness when facing diverse forgery patterns. Another underexplored aspect we observe is that different features often attend to the same forged region, resulting in redundant feature representations and limiting the diversity of the extracted clues. This may undermine the ability of a model to capture complementary information across different facets, thereby compromising its generalization capability to diverse manipulations. In this paper, we seek to tackle these challenges from two aspects: (1) we propose a triple-branch network that jointly captures spatial and frequency features by learning from both original image and image reconstructed by different frequency channels, and (2) we mathematically derive feature decoupling and fusion losses grounded in the mutual information theory, which enhances the model to focus on task-relevant features across the original image and the image reconstructed by different frequency channels. Extensive experiments on six large-scale benchmark datasets demonstrate that our method consistently achieves state-of-the-art performance. Our code is released at https://github.com/injooker/Unveiling Deepfake.

Sifan Wu, Amir Khasahmadi, Mor Katz et al.

Parametric Computer-Aided Design (CAD) is central to contemporary mechanical design. However, it encounters challenges in achieving precise parametric sketch modeling and lacks practical evaluation metrics suitable for mechanical design. We harness the capabilities of pre-trained foundation models, renowned for their successes in natural language processing and computer vision, to develop generative models specifically for CAD. These models are adept at understanding complex geometries and design reasoning, a crucial advancement in CAD technology. In this paper, we propose CadVLM, an end-to-end vision language model for CAD generation. Our approach involves adapting pre-trained foundation models to manipulate engineering sketches effectively, integrating both sketch primitive sequences and sketch images. Extensive experiments demonstrate superior performance on multiple CAD sketch generation tasks such as CAD autocompletion, CAD autoconstraint, and image conditional generation. To our knowledge, this is the first instance of a multimodal Large Language Model (LLM) being successfully applied to parametric CAD generation, representing a pioneering step in the field of computer-aided mechanical design.

Sifan Wu, Haipeng Chen, Yifang Yin et al.

Human pose estimation in videos has long been a compelling yet challenging task within the realm of computer vision. Nevertheless, this task remains difficult because of the complex video scenes, such as video defocus and self-occlusion. Recent methods strive to integrate multi-frame visual features generated by a backbone network for pose estimation. However, they often ignore the useful joint information encoded in the initial heatmap, which is a by-product of the backbone generation. Comparatively, methods that attempt to refine the initial heatmap fail to consider any spatio-temporal motion features. As a result, the performance of existing methods for pose estimation falls short due to the lack of ability to leverage both local joint (heatmap) information and global motion (feature) dynamics. To address this problem, we propose a novel joint-motion mutual learning framework for pose estimation, which effectively concentrates on both local joint dependency and global pixel-level motion dynamics. Specifically, we introduce a context-aware joint learner that adaptively leverages initial heatmaps and motion flow to retrieve robust local joint feature. Given that local joint feature and global motion flow are complementary, we further propose a progressive joint-motion mutual learning that synergistically exchanges information and interactively learns between joint feature and motion flow to improve the capability of the model. More importantly, to capture more diverse joint and motion cues, we theoretically analyze and propose an information orthogonality objective to avoid learning redundant information from multi-cues. Empirical experiments show our method outperforms prior arts on three challenging benchmarks.

Yizhan Li, Sifan Wu, Christopher Smith et al.

Writing clinical notes and documenting medical exams is a critical task for healthcare professionals, serving as a vital component of patient care documentation. However, manually writing these notes is time-consuming and can impact the amount of time clinicians can spend on direct patient interaction and other tasks. Consequently, the development of automated clinical note generation systems has emerged as a clinically meaningful area of research within AI for health. In this paper, we present three key contributions to the field of clinical note generation using large language models (LLMs). First, we introduce CliniKnote, a comprehensive dataset consisting of 1,200 complex doctor-patient conversations paired with their full clinical notes. This dataset, created and curated by medical experts with the help of modern neural networks, provides a valuable resource for training and evaluating models in clinical note generation tasks. Second, we propose the K-SOAP (Keyword, Subjective, Objective, Assessment, and Plan) note format, which enhances traditional SOAP~\cite{podder2023soap} (Subjective, Objective, Assessment, and Plan) notes by adding a keyword section at the top, allowing for quick identification of essential information. Third, we develop an automatic pipeline to generate K-SOAP notes from doctor-patient conversations and benchmark various modern LLMs using various metrics. Our results demonstrate significant improvements in efficiency and performance compared to standard LLM finetuning methods.

Yizhan Li, Florence Cloutier, Sifan Wu et al.

Generating molecules that satisfy precise numeric constraints over multiple physicochemical properties is critical and challenging. Although large language models (LLMs) are expressive, they struggle with precise multi-objective control and numeric reasoning without external structure and feedback. We introduce \textbf{M olGen}, a fragment-level, retrieval-augmented, two-stage framework for molecule generation under multi-property constraints. Stage I : Prototype generation: a multi-agent reasoner performs retrieval-anchored, fragment-level edits to produce a candidate near the feasible region. Stage II : RL-based fine-grained optimization: a fragment-level optimizer trained with Group Relative Policy Optimization (GRPO) applies one- or multi-hop refinements to explicitly minimize the property errors toward our target while regulating edit complexity and deviation from the prototype. A large, automatically curated dataset with reasoning chains of fragment edits and measured property deltas underpins both stages, enabling deterministic, reproducible supervision and controllable multi-hop reasoning. Unlike prior work, our framework better reasons about molecules by leveraging fragments and supports controllable refinement toward numeric targets. Experiments on generation under two sets of property constraints (QED, LogP, Molecular Weight and HOMO, LUMO) show consistent gains in validity and precise satisfaction of multi-property targets, outperforming strong LLMs and graph-based algorithms.

Ke Liang, Sifan Wu, Jiayi Gu

Using natural language processing (NLP) technologies to develop medical chatbots makes the diagnosis of the patient more convenient and efficient, which is a typical application in healthcare AI. Because of its importance, lots of research have been come out. Recently, the neural generative models have shown their impressive ability as the core of chatbot, while it cannot scale well when directly applied to medical conversation due to the lack of medical-specific knowledge. To address the limitation, a scalable Medical Knowledge Assisted mechanism, MKA, is proposed in this paper. The mechanism aims to assist general neural generative models to achieve better performance on the medical conversation task. The medical-specific knowledge graph is designed within the mechanism, which contains 6 types of medical-related information, including department, drug, check, symptom, disease, food. Besides, the specific token concatenation policy is defined to effectively inject medical information into the input data. Evaluation of our method is carried out on two typical medical datasets, MedDG and MedDialog-CN. The evaluation results demonstrate that models combined with our mechanism outperform original methods in multiple automatic evaluation metrics. Besides, MKA-Bert-GPT achieves state-of-the-art performance. The open-sourced codes are public: https://github.com/LIANGKE23/Knowledge_Assisted_Medical_Dialogue_Generation_Mechanism

Hangzhan Jin, Sicheng Lv, Sifan Wu et al.

Training large language models (LLMs) from scratch is increasingly impractical, making post-training methods such as supervised fine-tuning (SFT) and reinforcement-learning fine-tuning (RL-FT, e.g., PPO) central to modern practice. Using an out-of-distribution (OOD) variant of the 24-point card game and new spectrum-based diagnostics, we revisit how these two stages reshape model representation and OOD performance. Our key findings are- (1) RL-FT can restore much of the OOD performance loss from SFT (e.g., Llama-11B 8.97% to 15.38%, Qwen-7B 17.09% to 19.66%). But when SFT induces severe overfitting and a clear distribution shift, RL-FT cannot fully recover OOD performance. (2) Direction shifts of singular vectors matter more than singular value magnitudes. These shifts concentrate on directions linked to the largest and smallest singular values, leaving the bulk spectrum intact. (3) Low-rank and shallow recovery is effective: restoring singular vector directions for the top 20% of values or first 25% of layers recovers 70-80% of OOD performance. (4) Stronger SFT checkpoints enable better recovery by RL, while overfitted ones resist restoration. These results reconcile prior reports of RL superior OOD performance: RL primarily counteracts SFT-induced directional drift rather than finding new solutions. Our spectrum-aware analysis highlights inexpensive recovery knobs low-rank UV merging and shallow-layer resets that practitioners can use before costly RL fine-tuning.

Yingying Jiao, Zhigang Wang, Zhenguang Liu et al.

Human pose estimation has given rise to a broad spectrum of novel and compelling applications, including action recognition, sports analysis, as well as surveillance. However, accurate video pose estimation remains an open challenge. One aspect that has been overlooked so far is that existing methods learn motion clues from all pixels rather than focusing on the target human body, making them easily misled and disrupted by unimportant information such as background changes or movements of other people. Additionally, while the current Transformer-based pose estimation methods has demonstrated impressive performance with global modeling, they struggle with local context perception and precise positional identification. In this paper, we try to tackle these challenges from three aspects: (1) We propose a bilayer Human-Keypoint Mask module that performs coarse-to-fine visual token refinement, which gradually zooms in on the target human body and keypoints while masking out unimportant figure regions. (2) We further introduce a novel deformable cross attention mechanism and a bidirectional separation strategy to adaptively aggregate spatial and temporal motion clues from constrained surrounding contexts. (3) We mathematically formulate the deformable cross attention, constraining that the model focuses solely on the regions centered at the target person body. Empirically, our method achieves state-of-the-art performance on three large-scale benchmark datasets. A remarkable highlight is that our method achieves an 84.8 mean Average Precision (mAP) on the challenging wrist joint, which significantly outperforms the 81.5 mAP achieved by the current state-of-the-art method on the PoseTrack2017 dataset.

Haipeng Chen, Sifan Wu, Zhigang Wang et al.

Video-based human pose estimation has long been a fundamental yet challenging problem in computer vision. Previous studies focus on spatio-temporal modeling through the enhancement of architecture design and optimization strategies. However, they overlook the causal relationships in the joints, leading to models that may be overly tailored and thus estimate poorly to challenging scenes. Therefore, adequate causal reasoning capability, coupled with good interpretability of model, are both indispensable and prerequisite for achieving reliable results. In this paper, we pioneer a causal perspective on pose estimation and introduce a causal-inspired multitask learning framework, consisting of two stages. \textit{In the first stage}, we try to endow the model with causal spatio-temporal modeling ability by introducing two self-supervision auxiliary tasks. Specifically, these auxiliary tasks enable the network to infer challenging keypoints based on observed keypoint information, thereby imbuing causal reasoning capabilities into the model and making it robust to challenging scenes. \textit{In the second stage}, we argue that not all feature tokens contribute equally to pose estimation. Prioritizing causal (keypoint-relevant) tokens is crucial to achieve reliable results, which could improve the interpretability of the model. To this end, we propose a Token Causal Importance Selection module to identify the causal tokens and non-causal tokens (\textit{e.g.}, background and objects). Additionally, non-causal tokens could provide potentially beneficial cues but may be redundant. We further introduce a non-causal tokens clustering module to merge the similar non-causal tokens. Extensive experiments show that our method outperforms state-of-the-art methods on three large-scale benchmark datasets.

Yingying Jiao, Zhigang Wang, Sifan Wu et al.

Human pose estimation in videos remains a challenge, largely due to the reliance on extensive manual annotation of large datasets, which is expensive and labor-intensive. Furthermore, existing approaches often struggle to capture long-range temporal dependencies and overlook the complementary relationship between temporal pose heatmaps and visual features. To address these limitations, we introduce STDPose, a novel framework that enhances human pose estimation by learning spatiotemporal dynamics in sparsely-labeled videos. STDPose incorporates two key innovations: 1) A novel Dynamic-Aware Mask to capture long-range motion context, allowing for a nuanced understanding of pose changes. 2) A system for encoding and aggregating spatiotemporal representations and motion dynamics to effectively model spatiotemporal relationships, improving the accuracy and robustness of pose estimation. STDPose establishes a new performance benchmark for both video pose propagation (i.e., propagating pose annotations from labeled frames to unlabeled frames) and pose estimation tasks, across three large-scale evaluation datasets. Additionally, utilizing pseudo-labels generated by pose propagation, STDPose achieves competitive performance with only 26.7% labeled data.

Mengtao Zhou, Sifan Wu, Huan Zhang et al.

We investigate the capacity of Large Language Models (LLMs) for imaginative reasoning--the proactive construction, testing, and revision of hypotheses in information-sparse environments. Existing benchmarks, often static or focused on social deduction, fail to capture the dynamic, exploratory nature of this reasoning process. To address this gap, we introduce a comprehensive research framework based on the classic "Turtle Soup" game, integrating a benchmark, an agent, and an evaluation protocol. We present TurtleSoup-Bench, the first large-scale, bilingual, interactive benchmark for imaginative reasoning, comprising 800 turtle soup puzzles sourced from both the Internet and expert authors. We also propose Mosaic-Agent, a novel agent designed to assess LLMs' performance in this setting. To evaluate reasoning quality, we develop a multi-dimensional protocol measuring logical consistency, detail completion, and conclusion alignment. Experiments with leading LLMs reveal clear capability limits, common failure patterns, and a significant performance gap compared to humans. Our work offers new insights into LLMs' imaginative reasoning and establishes a foundation for future research on exploratory agent behavior.

Zhigang Wang, Shaojing Fan, Zhenguang Liu et al.

Human pose estimation, with its broad applications in action recognition and motion capture, has experienced significant advancements. However, current Transformer-based methods for video pose estimation often face challenges in managing redundant temporal information and achieving fine-grained perception because they only focus on processing low-resolution features. To address these challenges, we propose a novel multi-scale resolution framework that encodes spatio-temporal representations at varying granularities and executes fine-grained perception compensation. Furthermore, we employ a density peaks clustering method to dynamically identify and prioritize tokens that offer important semantic information. This strategy effectively prunes redundant feature tokens, especially those arising from multi-frame features, thereby optimizing computational efficiency without sacrificing semantic richness. Empirically, it sets new benchmarks for both performance and efficiency on three large-scale datasets. Our method achieves a 93.8% improvement in inference speed compared to the baseline, while also enhancing pose estimation accuracy, reaching 87.4 mAP on the PoseTrack2017 dataset.

Sifan Wu, Zhenguang Liu, Beibei Zhang et al.

Human motion copy is an intriguing yet challenging task in artificial intelligence and computer vision, which strives to generate a fake video of a target person performing the motion of a source person. The problem is inherently challenging due to the subtle human-body texture details to be generated and the temporal consistency to be considered. Existing approaches typically adopt a conventional GAN with an L1 or L2 loss to produce the target fake video, which intrinsically necessitates a large number of training samples that are challenging to acquire. Meanwhile, current methods still have difficulties in attaining realistic image details and temporal consistency, which unfortunately can be easily perceived by human observers. Motivated by this, we try to tackle the issues from three aspects: (1) We constrain pose-to-appearance generation with a perceptual loss and a theoretically motivated Gromov-Wasserstein loss to bridge the gap between pose and appearance. (2) We present an episodic memory module in the pose-to-appearance generation to propel continuous learning that helps the model learn from its past poor generations. We also utilize geometrical cues of the face to optimize facial details and refine each key body part with a dedicated local GAN. (3) We advocate generating the foreground in a sequence-to-sequence manner rather than a single-frame manner, explicitly enforcing temporal inconsistency. Empirical results on five datasets, iPER, ComplexMotion, SoloDance, Fish, and Mouse datasets, demonstrate that our method is capable of generating realistic target videos while precisely copying motion from a source video. Our method significantly outperforms state-of-the-art approaches and gains 7.2% and 12.4% improvements in PSNR and FID respectively.

Qianggang Ding, Sifan Wu, Hao Sun et al.

Recently, a variety of regularization techniques have been widely applied in deep neural networks, such as dropout, batch normalization, data augmentation, and so on. These methods mainly focus on the regularization of weight parameters to prevent overfitting effectively. In addition, label regularization techniques such as label smoothing and label disturbance have also been proposed with the motivation of adding a stochastic perturbation to labels. In this paper, we propose a novel adaptive label regularization method, which enables the neural network to learn from the erroneous experience and update the optimal label representation online. On the other hand, compared with knowledge distillation, which learns the correlation of categories using teacher network, our proposed method requires only a minuscule increase in parameters without cumbersome teacher network. Furthermore, we evaluate our method on CIFAR-10/CIFAR-100/ImageNet datasets for image recognition tasks and AGNews/Yahoo/Yelp-Full datasets for text classification tasks. The empirical results show significant improvement under all experimental settings.