Pedro Ribeiro

Fernanda Bufon Färber, Iago Alves Brito, Julia Soares Dollis et al.

While large language models (LLMs) show transformative potential in healthcare, their development remains focused on high-resource languages, creating a critical barrier for others as simple translation fails to capture unique clinical and cultural nuances, such as endemic diseases. To address this, we introduce MedPT, the first large-scale, real-world corpus for Brazilian Portuguese, comprising 384,095 authentic question-answer pairs from patient-doctor interactions. The dataset underwent a meticulous multi-stage curation protocol, using a hybrid quantitative-qualitative analysis to filter noise and contextually enrich thousands of ambiguous queries. We further augmented the corpus via LLM-driven annotation, classifying questions into seven semantic types to capture user intent. Our analysis reveals its thematic breadth (3,200 topics) and unique linguistic properties, like the natural asymmetry in patient-doctor communication. To validate its utility, we benchmark a medical specialty routing task: fine-tuning a 1.7B parameter model achieves an outstanding 94\% F1-score on a 20-class setup. Furthermore, our qualitative error analysis shows misclassifications are not random but reflect genuine clinical ambiguities (e.g., between comorbid conditions), proving the dataset's deep semantic richness. We publicly release MedPT to foster the development of more equitable, accurate, and culturally-aware medical technologies for the Portuguese-speaking world.

Iago Alves Brito, Julia Soares Dollis, Fernanda Bufon Färber et al.

The integration of large language models (LLMs) into virtual reality (VR) environments has opened new pathways for creating more immersive and interactive digital humans. By leveraging the generative capabilities of LLMs alongside multimodal outputs such as facial expressions and gestures, virtual agents can simulate human-like personalities and emotions, fostering richer and more engaging user experiences. This paper provides a comprehensive review of methods for enabling digital humans to adopt nuanced personality traits, exploring approaches such as zero-shot, few-shot, and fine-tuning. Additionally, it highlights the challenges of integrating LLM-driven personality traits into VR, including computational demands, latency issues, and the lack of standardized evaluation frameworks for multimodal interactions. By addressing these gaps, this work lays a foundation for advancing applications in education, therapy, and gaming, while fostering interdisciplinary collaboration to redefine human-computer interaction in VR.

Julia S. Dollis, Iago A. Brito, Fernanda B. Färber et al.

While virtual reality (VR) excels at simulating physical environments, its effectiveness for training complex interpersonal skills is limited by a lack of psychologically plausible virtual humans. This is a critical gap in high-stakes domains like medical education, where communication is a core competency. This paper introduces a framework that integrates large language models (LLMs) into immersive VR to create medically coherent virtual patients with distinct, consistent personalities, built on a modular architecture that decouples personality from clinical data. We evaluated our system in a mixed-method, within-subjects study with licensed physicians who engaged in simulated consultations. Results demonstrate that the approach is not only feasible but is also perceived by physicians as a highly rewarding and effective training enhancement. Furthermore, our analysis uncovers critical design principles, including a ``realism-verbosity paradox" where less communicative agents can seem more artificial, and the need for challenges to be perceived as authentic to be instructive. This work provides a validated framework and key insights for developing the next generation of socially intelligent VR training environments.