Xin Li

Zikun Zhou, Yushuai Sun, Wenjie Pei et al.

The traditional paradigm to update retrieval models requires re-computing the embeddings of the gallery data, a time-consuming and computationally intensive process known as backfilling. To circumvent backfilling, Backward-Compatible Learning (BCL) has been widely explored, which aims to train a new model compatible with the old one. Many previous works focus on effectively aligning the embeddings of the new model with those of the old one to enhance the backward-compatibility. Nevertheless, such strong alignment constraints would compromise the discriminative ability of the new model, particularly when different classes are closely clustered and hard to distinguish in the old feature space. To address this issue, we propose to relax the constraints by introducing perturbations to the old feature prototypes. This allows us to align the new feature space with a pseudo-old feature space defined by these perturbed prototypes, thereby preserving the discriminative ability of the new model in backward-compatible learning. We have developed two approaches for calculating the perturbations: Neighbor-Driven Prototype Perturbation (NDPP) and Optimization-Driven Prototype Perturbation (ODPP). Particularly, they take into account the feature distributions of not only the old but also the new models to obtain proper perturbations along with new model updating. Extensive experiments on the landmark and commodity datasets demonstrate that our approaches perform favorably against state-of-the-art BCL algorithms.

Xin Li, Kaixiang Yang, Qiang Li et al.

Dual-view mammography, including craniocaudal (CC) and mediolateral oblique (MLO) projections, offers complementary anatomical views crucial for breast cancer diagnosis. However, in real-world clinical workflows, one view may be missing, corrupted, or degraded due to acquisition errors or compression artifacts, limiting the effectiveness of downstream analysis. View-to-view translation can help recover missing views and improve lesion alignment. Unlike natural images, this task in mammography is highly challenging due to large non-rigid deformations and severe tissue overlap in X-ray projections, which obscure pixel-level correspondences. In this paper, we propose Column-Aware and Implicit 3D Diffusion (CA3D-Diff), a novel bidirectional mammogram view translation framework based on conditional diffusion model. To address cross-view structural misalignment, we first design a column-aware cross-attention mechanism that leverages the geometric property that anatomically corresponding regions tend to lie in similar column positions across views. A Gaussian-decayed bias is applied to emphasize local column-wise correlations while suppressing distant mismatches. Furthermore, we introduce an implicit 3D structure reconstruction module that back-projects noisy 2D latents into a coarse 3D feature volume based on breast-view projection geometry. The reconstructed 3D structure is refined and injected into the denoising UNet to guide cross-view generation with enhanced anatomical awareness. Extensive experiments demonstrate that CA3D-Diff achieves superior performance in bidirectional tasks, outperforming state-of-the-art methods in visual fidelity and structural consistency. Furthermore, the synthesized views effectively improve single-view malignancy classification in screening settings, demonstrating the practical value of our method in real-world diagnostics.

Rui Yang, Huitao Li, Matthew Yu Heng Wong et al.

Natural language processing (NLP) has been traditionally applied to medicine, and generative large language models (LLMs) have become prominent recently. However, the differences between them across different medical tasks remain underexplored. We analyzed 19,123 studies, finding that generative LLMs demonstrate advantages in open-ended tasks, while traditional NLP dominates in information extraction and analysis tasks. As these technologies advance, ethical use of them is essential to ensure their potential in medical applications.