Hongchao Shu

Hao Ding, Lalithkumar Seenivasan, Hongchao Shu et al.

Large language model-based (LLM) agents are emerging as a powerful enabler of robust embodied intelligence due to their capability of planning complex action sequences. Sound planning ability is necessary for robust automation in many task domains, but especially in surgical automation. These agents rely on a highly detailed natural language representation of the scene. Thus, to leverage the emergent capabilities of LLM agents for surgical task planning, developing similarly powerful and robust perception algorithms is necessary to derive a detailed scene representation of the environment from visual input. Previous research has focused primarily on enabling LLM-based task planning while adopting simple yet severely limited perception solutions to meet the needs for bench-top experiments, but lacks the critical flexibility to scale to less constrained settings. In this work, we propose an alternate perception approach -- a digital twin (DT)-based machine perception approach that capitalizes on the convincing performance and out-of-the-box generalization of recent vision foundation models. Integrating our DT representation and LLM agent for planning with the dVRK platform, we develop an embodied intelligence system and evaluate its robustness in performing peg transfer and gauze retrieval tasks. Our approach shows strong task performance and generalizability to varied environmental settings. Despite a convincing performance, this work is merely a first step towards the integration of DT representations. Future studies are necessary for the realization of a comprehensive DT framework to improve the interpretability and generalizability of embodied intelligence in surgery.

Zhaoshuo Li, Hongchao Shu, Ruixing Liang et al.

Purpose: Tracking the 3D motion of the surgical tool and the patient anatomy is a fundamental requirement for computer-assisted skull-base surgery. The estimated motion can be used both for intra-operative guidance and for downstream skill analysis. Recovering such motion solely from surgical videos is desirable, as it is compliant with current clinical workflows and instrumentation. Methods: We present Tracker of Anatomy and Tool (TAToo). TAToo jointly tracks the rigid 3D motion of patient skull and surgical drill from stereo microscopic videos. TAToo estimates motion via an iterative optimization process in an end-to-end differentiable form. For robust tracking performance, TAToo adopts a probabilistic formulation and enforces geometric constraints on the object level. Results: We validate TAToo on both simulation data, where ground truth motion is available, as well as on anthropomorphic phantom data, where optical tracking provides a strong baseline. We report sub-millimeter and millimeter inter-frame tracking accuracy for skull and drill, respectively, with rotation errors below 1°. We further illustrate how TAToo may be used in a surgical navigation setting. Conclusion: We present TAToo, which simultaneously tracks the surgical tool and the patient anatomy in skull-base surgery. TAToo directly predicts the motion from surgical videos, without the need of any markers. Our results show that the performance of TAToo compares favorably to competing approaches. Future work will include fine-tuning of our depth network to reach a 1 mm clinical accuracy goal desired for surgical applications in the skull base.

Shuyue Stella Li, Xiangyu Zhang, Shu Zhou et al.

With careful manipulation, malicious agents can reverse engineer private information encoded in pre-trained language models. Security concerns motivate the development of quantum pre-training. In this work, we propose a highly Portable Quantum Language Model (PQLM) that can easily transmit information to downstream tasks on classical machines. The framework consists of a cloud PQLM built with random Variational Quantum Classifiers (VQC) and local models for downstream applications. We demonstrate the ad hoc portability of the quantum model by extracting only the word embeddings and effectively applying them to downstream tasks on classical machines. Our PQLM exhibits comparable performance to its classical counterpart on both intrinsic evaluation (loss, perplexity) and extrinsic evaluation (multilingual sentiment analysis accuracy) metrics. We also perform ablation studies on the factors affecting PQLM performance to analyze model stability. Our work establishes a theoretical foundation for a portable quantum pre-trained language model that could be trained on private data and made available for public use with privacy protection guarantees.

Hongchao Shu, Ruixing Liang, Zhaoshuo Li et al.

Purpose: Digital twins are virtual interactive models of the real world, exhibiting identical behavior and properties. In surgical applications, computational analysis from digital twins can be used, for example, to enhance situational awareness. Methods: We present a digital twin framework for skull-base surgeries, named Twin-S, which can be integrated within various image-guided interventions seamlessly. Twin-S combines high-precision optical tracking and real-time simulation. We rely on rigorous calibration routines to ensure that the digital twin representation precisely mimics all real-world processes. Twin-S models and tracks the critical components of skull-base surgery, including the surgical tool, patient anatomy, and surgical camera. Significantly, Twin-S updates and reflects real-world drilling of the anatomical model in frame rate. Results: We extensively evaluate the accuracy of Twin-S, which achieves an average 1.39 mm error during the drilling process. We further illustrate how segmentation masks derived from the continuously updated digital twin can augment the surgical microscope view in a mixed reality setting, where bone requiring ablation is highlighted to provide surgeons additional situational awareness. Conclusion: We present Twin-S, a digital twin environment for skull-base surgery. Twin-S tracks and updates the virtual model in real-time given measurements from modern tracking technologies. Future research on complementing optical tracking with higher-precision vision-based approaches may further increase the accuracy of Twin-S.

Hao Ding, Yuqian Zhang, Tuxun Lu et al.

Surgical data science has seen rapid advancement due to the excellent performance of end-to-end deep neural networks (DNNs) for surgical video analysis. Despite their successes, end-to-end DNNs have been proven susceptible to even minor corruptions, substantially impairing the model's performance. This vulnerability has become a major concern for the translation of cutting-edge technology, especially for high-stakes decision-making in surgical data science. We introduce SegSTRONG-C, a benchmark and challenge in surgical data science dedicated, aiming to better understand model deterioration under unforeseen but plausible non-adversarial corruption and the capabilities of contemporary methods that seek to improve it. Through comprehensive baseline experiments and participating submissions from widespread community engagement, SegSTRONG-C reveals key themes for model failure and identifies promising directions for improving robustness. The performance of challenge winners, achieving an average 0.9394 DSC and 0.9301 NSD across the unreleased test sets with corruption types: bleeding, smoke, and low brightness, shows inspiring improvement of 0.1471 DSC and 0.2584 NSD in average comparing to strongest baseline methods with UNet architecture trained with AutoAugment. In conclusion, the SegSTRONG-C challenge has identified some practical approaches for enhancing model robustness, yet most approaches relied on conventional techniques that have known, and sometimes quite severe, limitations. Looking ahead, we advocate for expanding intellectual diversity and creativity in non-adversarial robustness beyond data augmentation or training scale, calling for new paradigms that enhance universal robustness to corruptions and may enable richer applications in surgical data science.

Hongchao Shu, Roger D. Soberanis-Mukul, Jiru Xu et al.

Accurate intra-operative localization of the bronchoscope tip relative to patient anatomy remains challenging due to respiratory motion, anatomical variability, and CT-to-body divergence that cause deformation and misalignment between intra-operative views and pre-operative CT. Existing vision-based methods often fail to generalize across domains and patients, leading to residual alignment errors. This work establishes a generalizable foundation for bronchoscopy navigation through a robust vision-based framework and a new synthetic benchmark dataset that enables standardized and reproducible evaluation. We propose a vision-based pose optimization framework for frame-wise 2D-3D registration between intra-operative endoscopic views and pre-operative CT anatomy. A fine-tuned modality- and domain-invariant encoder enables direct similarity computation between real endoscopic RGB frames and CT-rendered depth maps, while a differentiable rendering module iteratively refines camera poses through depth consistency. To enhance reproducibility, we introduce the first public synthetic benchmark dataset for bronchoscopy navigation, addressing the lack of paired CT-endoscopy data. Trained exclusively on synthetic data distinct from the benchmark, our model achieves an average translational error of 2.65 mm and a rotational error of 0.19 rad, demonstrating accurate and stable localization. Qualitative results on real patient data further confirm strong cross-domain generalization, achieving consistent frame-wise 2D-3D alignment without domain-specific adaptation. Overall, the proposed framework achieves robust, domain-invariant localization through iterative vision-based optimization, while the new benchmark provides a foundation for standardized progress in vision-based bronchoscopy navigation.

Hongchao Shu, Lalithkumar Seenivasan, Mingxu Liu et al.

Arthroscopic procedures can greatly benefit from navigation systems that enhance spatial awareness, depth perception, and field of view. However, existing optical tracking solutions impose strict workspace constraints and disrupt surgical workflow. Vision-based alternatives, though less invasive, often rely solely on the monocular arthroscope camera, making them prone to drift, scale ambiguity, and sensitivity to rapid motion or occlusion. We propose DualVision ArthroNav, a multi-camera arthroscopy navigation system that integrates an external camera rigidly mounted on the arthroscope. The external camera provides stable visual odometry and absolute localization, while the monocular arthroscope video enables dense scene reconstruction. By combining these complementary views, our system resolves the scale ambiguity and long-term drift inherent in monocular SLAM and ensures robust relocalization. Experiments demonstrate that our system effectively compensates for calibration errors, achieving an average absolute trajectory error of 1.09 mm. The reconstructed scenes reach an average target registration error of 2.16 mm, with high visual fidelity (SSIM = 0.69, PSNR = 22.19). These results indicate that our system provides a practical and cost-efficient solution for arthroscopic navigation, bridging the gap between optical tracking and purely vision-based systems, and paving the way toward clinically deployable, fully vision-based arthroscopic guidance.

Han Zhang, Lalithkumar Seenivasan, Jose L. Porras et al.

Observing surgical practice has historically relied on fixed vantage points or recollections, leaving the egocentric visual perspectives that guide clinical decisions undocumented. Fixed-camera video can capture surgical workflows at the room-scale, but cannot reconstruct what each team member actually saw. Thus, these videos only provide limited insights into how decisions that affect surgical safety, training, and workflow optimization are made. Here we introduce EgoSurg, the first framework to reconstruct the dynamic, egocentric replays for any operating room (OR) staff directly from wall-mounted fixed-camera video, and thus, without intervention to clinical workflow. EgoSurg couples geometry-driven neural rendering with diffusion-based view enhancement, enabling high-visual fidelity synthesis of arbitrary and egocentric viewpoints at any moment. In evaluation across multi-site surgical cases and controlled studies, EgoSurg reconstructs person-specific visual fields and arbitrary viewpoints with high visual quality and fidelity. By transforming existing OR camera infrastructure into a navigable dynamic 3D record, EgoSurg establishes a new foundation for immersive surgical data science, enabling surgical practice to be visualized, experienced, and analyzed from every angle.

Hao Ding, Yuqian Zhang, Wenzheng Cheng et al.

Surgical phase recognition (SPR) is an integral component of surgical data science, enabling high-level surgical analysis. End-to-end trained neural networks that predict surgical phase directly from videos have shown excellent performance on benchmarks. However, these models struggle with robustness due to non-causal associations in the training set. Our goal is to improve model robustness to variations in the surgical videos by leveraging the digital twin (DT) paradigm -- an intermediary layer to separate high-level analysis (SPR) from low-level processing. As a proof of concept, we present a DT representation-based framework for SPR from videos. The framework employs vision foundation models with reliable low-level scene understanding to craft DT representation. We embed the DT representation in place of raw video inputs in the state-of-the-art SPR model. The framework is trained on the Cholec80 dataset and evaluated on out-of-distribution (OOD) and corrupted test samples. Contrary to the vulnerability of the baseline model, our framework demonstrates strong robustness on both OOD and corrupted samples, with a video-level accuracy of 80.3 on a highly corrupted Cholec80 test set, 67.9 on the challenging CRCD dataset, and 99.8 on an internal robotic surgery dataset, outperforming the baseline by 3.9, 16.8, and 90.9 respectively. We also find that using DT representation as an augmentation to the raw input can significantly improve model robustness. Our findings lend support to the thesis that DT representations are effective in enhancing model robustness. Future work will seek to improve the feature informativeness and incorporate interpretability for a more comprehensive framework.

Jiaming Zhang, Mingxu Liu, Hongchao Shu et al.

Surgical navigation provides real-time guidance by estimating the pose of patient anatomy and surgical instruments to visualize relevant intraoperative information. In conventional systems, instruments are typically tracked using fiducial markers and stationary optical tracking systems (OTS). Augmented reality (AR) has further enabled intuitive visualization and motivated tracking using sensors embedded in head-mounted displays (HMDs). However, most existing approaches rely on a clear line of sight, which is difficult to maintain in dynamic operating room environments due to frequent occlusions caused by equipment, surgical tools, and personnel. This work introduces a framework for tracking surgical instruments under occlusion by fusing multiple sensing modalities within a dynamic scene graph representation. The proposed approach integrates tracking systems with different accuracy levels and motion characteristics while estimating tracking reliability in real time. Experimental results demonstrate improved robustness and enhanced consistency of AR visualization in the presence of occlusions.